enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 11 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Digestizyme-BHoltraCeuticals100 mg
- DigestMore UltraRenew Lifein a blend
- DigestRiteNewtonEverett · off the market50 mg
- DigestWellLive Consciousin a blend
- DigestxymU.S. Enzymesin a blend
- Digestxym+U.S. Enzymesin a blend
- Digestzyme-VOrtho Molecular Productsin a blend
- Disc- ZYMNutri-West100 mg
- Double Strength ZymactiveNatural Factors171.44 mg
- Double Strength Zymactive Proteolytic EnzymesNatural Factors · off the market240 mg
- DuoZymeKaruna100 mg
- Dynamic Fruits & Greens BerryNutri-Dynin a blend
- Dypan-ACMWonder Laboratories150 mg
- DyzimeDC50 mg
- Dyzime-ACMDC150 mg
- Earth Genius Men's MultivitaminGNC Earth Genius · off the marketin a blend
- Earth Source Multi-NutrientSolgar20 mg
- Earth's Green Essentialstnvitaminsin a blend
- Earthy Andy Plant Powered Protein Tahitian VanillaNB Pure Pure Veganin a blend
- Easy Digest1-800-WellMed · off the marketin a blend
- EcoGreen MultiNOW · off the market12.5 mg
- EcoGreen Multi Iron-FreeNOW12.5 mg
- Electro-Vita-MinTrace Minerals Research · off the marketin a blend
- Electro-Vita-Min Daily 5Trace Minerals Researchin a blend
- Elite Green ProteinHealthForce SuperFoodsin a blend
- Elite Green Protein Cool GreenWarrior Forcein a blend
- Elite Green Protein Elite MesquiteWarriorForce · off the marketin a blend
- Elite Green Protein Elite MesquiteWarrior Force · off the marketin a blend
- Elite MultivitaminPurity Products25 mg
- Energize GreensHolistic Labs Ltd.in a blend
- Enhanced Energy Once Daily Whole Food MultivitaminKALin a blend
- Enhanced Energy Teen Stay Sharp MultivitaminKALin a blend
- Enhanced Energy Whole Food Multivitamin Mango Pineapple FlavorKALin a blend
- Enxymix GFCFNeurobiologixin a blend
- Enz-FlameDaVinci Laboratoriesin a blend
- EnzaidEndo-met Laboratories49 mg
- EnzalaseMaster Supplements Incorporated · off the marketin a blend
- EnzalaseMaster Supplementsin a blend
- EnzalaseProMaster Supplementsin a blend
- Enzflame Kids Powdered Drink MixLittle DaVinciin a blend
- Enzorb Digestive EnzymesSunwarriorin a blend
- Enzy-GestPriority One Nutritional Supplements100 mg
- EnzyBioticAerobic Life · off the marketin a blend
- Enzym-Complete/DDP-IVKirkmananother unit
- Enzym-Complete/DPP-IV II With IsogestKirkmananother unit
- Enzyme 13Nature's Bountyanother unit
- Enzyme BalanceNature's Labin a blend
- Enzyme BenefitsDaVinci Benefits Line0.89 mg
- Enzyme Blend - AM PacketGNC Preventive Nutritionin a blend
- Enzyme Blend - PM PacketGNC Preventive Nutritionin a blend