enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 12 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Enzyme CapsVSN Vital Strength Nutrition · off the market100 mg
- Enzyme CapsVitaCeutical Labs100 mg
- Enzyme CapsVitamer Laboratories200 mg
- Enzyme CapsuleBronson Laboratoriesanother unit
- Enzyme Complete DPP-IV with IsogestKirkmanin a blend
- Enzyme Complex With HerbsVSN Vital Strength Nutrition · off the marketanother unit
- Enzyme Digest 423 mgQuest · off the market100 mg
- Enzyme Digestive AidNeoLife Nutritionals200 mg
- Enzyme Formula Proteolytic EnzymesDr. Sierra's Naturals125 mg
- Enzyme ForteFoster Regal65 mg
- Enzyme Probiotic ComplexAmerican Healthanother unit
- Enzyme RestoreTaylor MD Formulationsin a blend
- Enzyme TabsWonder Laboratories65 mg
- Enzyme-Complete with DDP-IVKirkmanin a blend
- EnzymeComplex+Herbs SRA72 mg
- EnzymeMD1MDin a blend
- EnzymeMD1MD Nutritionin a blend
- EnzymesSmarter Nutritionin a blend
- Enzymes +New Earthin a blend
- Enzymes + Enjoy Meals AgainNew Earth Wild Essentials · off the marketin a blend
- Enzymes-HClProtocol For Life Balance2 mg
- Essential4 Today · off the marketin a blend
- Essential DigestionLogos Nutritionals24 mg
- Essential Digestive Enzymes 800 mgDouble Wood Supplementsin a blend
- Essential Life CapsulesCountry Lifein a blend
- Essential Prostate PackSupplement Spotin a blend
- Essential-4 Nutrition PackDouglas Laboratories50 mg
- Essentially AllRoexin a blend
- Essentials Complete MultivitaminDoctor Gilmorein a blend
- Essentials Perfomance Formula MultiVitamin And MineralMartin Avenue Pharmacy6.7 mg
- Essentialzymes-4 Immediate Release CapsuleYoung Living Essential Oilsin a blend
- Everyday Energy FormulaCATALOin a blend
- ExcellacorAST Enzymesin a blend
- Extra Care Digest SmartRenew Lifein a blend
- Extra Strength ClenZymeNatural Factors5.5 mg
- Extra Strength Gluten ReliefNatural Factors7.5 mg
- Extra-Strength ibuActinSolaray · off the market75 mg
- Extra-Strength ibuActin PMSolaray75 mg
- Ezgest RXAmazeRx · off the market100 mg
- FamilyGarden of Life Vitamin Codein a blend
- Farklempt Boich digestive enzymesEcological Formulas60 mg
- Female Super PackDouglas Laboratories48 mg
- Fenugreek PlusBotanic Choice250 mg
- Fermented Digestive GreensSoTru · off the marketin a blend
- FiberMaxMaxi Healthin a blend
- Fibrenza Systemic Enzyme 500 mgHCP Formulasin a blend
- FibrestoreRelivin a blend
- Fibrestore Orange FlavorRelivin a blend
- FibroVera AHSArthur Andrew Medicalin a blend
- FibroVera AHS 730 mgArthur Andrew Medical · off the marketin a blend