enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 13 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- FitMiss BurnMusclePharmin a blend
- FlarFXDr. Tobiasin a blend
- Flatter MeHUMin a blend
- Flex 19IVL Institute For Vibrant Living25 mg
- Flex Solve 24/7American BioSciences4 mg
- Flex-MendEnzyme Scienceanother unit
- FlexiAidNutracraftin a blend
- FlexLogicNulogic Nutritionals200 mg
- FloraVita With Probiotics, Prebiotics, Enzymes And HerbsTriVitaanother unit
- Food EnzymesNature's Sunshinein a blend
- For Him Fertility SupportBluebonnet Intimate Essentialsin a blend
- For Women OnlyOnly Natural · off the marketin a blend
- Formula 115DC65 mg
- From the EarthThe Vitamin Shoppeanother unit
- From The Earth No-IronThe Vitamin Shoppeanother unit
- Fruit & Greens PhytoFoodsNOWin a blend
- Fruitein Banana Orange CremeNature's Plus · off the market30 mg
- Fruitein Luscious Blue FruitNature's Plus · off the market30 mg
- Fruitein RainbowNature's Plus · off the market30 mg
- Fruitein Revitalizing Green Foods Natural Tropical Fruit FlavorNature's Plus · off the market30 mg
- Fruitien Acai 2500 mgNature's Plus · off the market30 mg
- Fruitien High Protein Energy Shake Exotic Red FruitNature's Plus · off the market30 mg
- Fuel 360 Strawberry LimePMD Platinumin a blend
- Fuel 360 WatermelonPMD Platinumin a blend
- Full Of Energy Senior MultiVitaCeutical Labs · off the market20 mg
- Full Spectrum Daily Digestive EnzymesIrwin Naturals · off the marketanother unit
- Full Spectrum Daily MultipleHealthy Choice Naturalsin a blend
- Full Spectrum EnzymesDr. Mercolain a blend
- Full Spectrum Enzymes for WomenDr. Mercolain a blend
- Full Spectrum Optimum EnzymesBluebonnet25 mg
- FyiGarden of Lifein a blend
- FYI RestoreGarden of Lifein a blend
- Gainer Milk ChocolateEPIQ · off the market50 mg
- Gas-EzeChristopher's Original Formulas · off the marketin a blend
- GasEChristopher's Original Formulasin a blend
- GastrEnzAdvanced Formula · off the marketin a blend
- GastrEnzProSol · off the marketin a blend
- Gastri-GestPriority One Nutritional Supplementsin a blend
- Gastric Acid DefenseDrFormulasin a blend
- Gastro Calm PlusPrescribed Choice · off the marketin a blend
- Gastro Digest IIVerVita50 mg
- Gastro-CalmOL Olympian Labsin a blend
- Gastro-IBSBronson Laboratoriesin a blend
- GastronexNorth American Herb & Spicein a blend
- Genessenntials Spectra SNPDaVinci Laboratories Of Vermont · off the market2 mg
- GenEssential DigestionGenesis Today · off the marketanother unit
- GenEssentials GreensGenesis Today25 mg
- Ges-CidNutri-Westin a blend
- GestaplexPhysician's Strengthin a blend
- Gestazyme Digestive EnzymesAmerican Health130 mg