Advantage Plus II

by Douglas Laboratories · capsule · 100 capsules

  • On the market (NIH)
  • UPC 3 10539 00338 1
  • DSLD label 8772
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 50 servings

Advantage Plus II by Douglas Laboratories lists 8 ingredients, 8 with an amount per serving of 2 capsules, such as 10 mg of niacin, 10 mg of vitamin B6, 400 mg of lecithin and 300 mg of polysaccharides. Its current label entered the NIH Dietary Supplement Label Database on June 1, 2012.

What is in Advantage Plus II?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advantage Plus II: Supplement Facts rows against the market (DSLD label 8772, January 2026 release)
IngredientAmount% DVAmong products listing it
Niacin10 mg50%Niacin in Advantage Plus II against 12,413 products10 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg10 mg

77% of 12,413 products listing niacin give more (median 20 mg).

Vitamin B6as Pyridoxine HydrochlorideVitamin B-6 (Form: as Pyridoxine HCl)10 mg500%Vitamin B6 in Advantage Plus II against 15,277 products10 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg10 mg

Higher than 55% of 15,277 products listing vitamin B6 (median 6 mg).

Lecithinas Soya400 mgLecithin in Advantage Plus II against 804 products400 mg per serving; the middle half of products list 50 mg to 1,200 mg, the median 200 mg.400 mg

Higher than 57% of 804 products listing lecithin (median 200 mg).

Polysaccharidesas CarrageenanPolysaccharides (Form: from Carrageenan)300 mgPolysaccharide in Advantage Plus II against 57 products300 mg per serving; the middle half of products list 150 mg to 2,800 mg, the median 550 mg.300 mg

60% of 57 products listing polysaccharide give more (median 550 mg).

Mucopolysaccharides100 mg
Edta100 mgEDTA in Advantage Plus II against 50 products100 mg per serving; the middle half of products list 200 mg to 500 mg, the median 300 mg.100 mg

80% of 50 products listing EDTA give more (median 300 mg).

Cholineas Choline BitartrateCholine (Form: from Choline Bitartrate)50 mg9%*Choline in Advantage Plus II against 4,738 products50 mg per serving; the middle half of products list 18 mg to 100 mg, the median 40 mg.DV 550 mgUL 3,500 mg50 mg

Higher than 54% of 4,738 products listing choline (median 40 mg).

Papain50 mgPapain in Advantage Plus II against 607 products50 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.50 mg

Higher than 55% of 607 products listing papain (median 40 mg).

* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.

Source: NIH ODS Dietary Supplement Label Database, label 8772 (entered June 1, 2012), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Advantage Plus II's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: As a dietary supplement, adults take 1 to 2 capsules daily or as directed by your healthcare professional.
Warnings
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
Allergens and what it does not contain
This product contains NO yeast, wheat gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Source: label statements in DSLD label 8772.

What else is on the label?

Other ingredients: Gelatin, Cellulose, Silicon Dioxide, Vegetable Stearate.

How many labels does Advantage Plus II have?

One label is on file, entered on June 1, 2012.

  1. Label 8772 (current) Entered June 1, 2012 · on the market · 100 capsules · UPC 3 10539 00338 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Douglas Laboratories (manufacturer), Pittsburgh, PA. All Douglas Laboratories products.

Where next?