PlainVitamins

Digestizyme-B

by HoltraCeuticals · capsule · 180 capsules

  • On the market (NIH)
  • DSLD label 270202
  • Serving 2 capsules
  • 90 servings

Digestizyme-B by HoltraCeuticals lists 9 ingredients, 9 with an amount per serving of 2 capsules, such as 100 mg of papain, 20 mg of bromelain, 60 mg of rutin and 35 mg of trypsin. Its current label entered the NIH Dietary Supplement Label Database on September 22, 2022.

What is in Digestizyme-B?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Digestizyme-B: Supplement Facts rows against the market (DSLD label 270202, January 2026 release)
IngredientAmount% DVAmong products listing it
Pancreatin6X100 mg
Papain100 mgPapain in Digestizyme-B against 607 products100 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.100 mg

Higher than 77% of 607 products listing papain (median 40 mg). Per day at the most servings: 300 mg.

Bromelain20 mgBromelain in Digestizyme-B against 1,337 products20 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.20 mg

78% of 1,337 products listing bromelain give more (median 50 mg). Per day at the most servings: 60 mg.

Rutin60 mgRutin in Digestizyme-B against 1,232 products60 mg per serving; the middle half of products list 10 mg to 50 mg, the median 25 mg.60 mg

Higher than 81% of 1,232 products listing rutin (median 25 mg). Per day at the most servings: 180 mg.

Trypsin35 mgTrypsin in Digestizyme-B against 77 products35 mg per serving; the middle half of products list 35 mg to 100 mg, the median 75 mg.35 mg

71% of 77 products listing trypsin give more (median 75 mg). Per day at the most servings: 105 mg.

Amylase42 mgAmylase in Digestizyme-B against 326 products42 mg per serving; the middle half of products list 5 mg to 50 mg, the median 14 mg.42 mg

Higher than 70% of 326 products listing amylase (median 14 mg). Per day at the most servings: 126 mg.

Serratiopeptidase1 mgSerratiopeptidase in Digestizyme-B against 64 products1 mg per serving; the middle half of products list 16.25 mg to 74.25 mg, the median 33 mg.1 mg

98% of 64 products listing serratiopeptidase give more (median 33 mg). Per day at the most servings: 3 mg.

Alpha-Chymotrypsin1 mgChymotrypsin in Digestizyme-B against 49 products1 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.1 mg

80% of 49 products listing chymotrypsin give more (median 3 mg). Per day at the most servings: 3 mg.

Pancrelipase50 mg
Pepsin100 mgPepsin in Digestizyme-B against 223 products100 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.100 mg

Higher than 70% of 223 products listing pepsin (median 50 mg). Per day at the most servings: 300 mg.

Betaine HCl250 mgBetaine Hydrochloride in Digestizyme-B against 914 products250 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.250 mg

Higher than 80% of 914 products listing betaine hydrochloride (median 50 mg). Per day at the most servings: 750 mg.

Source: NIH ODS Dietary Supplement Label Database, label 270202 (entered September 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 98% of the 64 products that print an amount of serratiopeptidase list more than its 1 mg of serratiopeptidase (median 33 mg).

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Digestizyme-B's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: 2 capsules with each meal.
Warnings
Keep out of reach of children.
Warning: If you are under medical supervision, seek the advice of your physician or healthcare professional prior to the use of this product.
Individuals with autoimmune conditions, depressive disorders, or pregnant/lactating women should consult their physician prior to use.
Storage
Store in a cool, dry place protected from light.

Source: label statements in DSLD label 270202.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Gelatin.

How many labels does Digestizyme-B have?

2 labels are on file under this name since March 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 270202 (current) Entered September 22, 2022 · on the market · 180 capsules
  2. Label 19413 Entered March 25, 2013 · off the market November 23, 2021 · 180 capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Kent Holtorf, MD and the Holtorf Medical Group, Inc. (distributor), Torrance, CA. All HoltraCeuticals products.

Where next?