Karuna · Non-Nutrient/Non-Botanical supplement

DuoZyme

Name: DuoZyme, Supplement Label Data
Creator: PlainVitamins
License: https://creativecommons.org/publicdomain/zero/1.0/

15 ingredients on file in the NIH Dietary Supplement Label Database, top 26% by ingredient count. Currently on-market in the U.S.

Compiled by PlainVitamins · August 14, 2026

15
Ingredients: Top 26%
By ingredient count: 9
Nutrient categories

On Market by Karuna Verify with NIH DSLD → · FDA overview →

DuoZyme is a non-nutrient/non-botanical supplement by Karuna in capsule form, listing 15 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Type: ⚗️ Non-Nutrient/Non-Botanical
Form: Capsule
Database Entry Date: 2013-08-23
Ingredients: 15

Supplement Facts (15 Ingredients)

Betaine HCl

Betaine Hydrochloride

Amount: Not disclosed on label
% DV: Not reported

Glutamic Acid Hydrochloride

Glutamic Acid

Amount: Not disclosed on label
% DV: Not reported

Papain

Amount: Not disclosed on label
% DV: Not reported

Pepsin

Amount: Not disclosed on label
% DV: Not reported

Pancreatin

Amount: Not disclosed on label
% DV: Not reported

Ox Bile extract

Bile

Amount: Not disclosed on label
% DV: Not reported

Providing at least the following

Header

Amount: Not disclosed on label
% DV: Not reported

Protease

Proteolytic Enzymes (Proteases)

Amount: Not disclosed on label
% DV: Not reported

Amylase

Amount: Not disclosed on label
% DV: Not reported

Lipase

Amount: Not disclosed on label
% DV: Not reported

Capsule

capsule

Amount: Not disclosed on label
% DV: Not reported

Silica

Silicon

Amount: Not disclosed on label
% DV: Not reported

Stearic Acid

Amount: Not disclosed on label
% DV: Not reported

Vegetable Stearate

Magnesium stearate

Amount: Not disclosed on label
% DV: Not reported

Maltodextrin

Amount: Not disclosed on label
% DV: Not reported

Ingredient	Group	Amount	% DV
Betaine HCl	Betaine Hydrochloride	Not disclosed on label	Not reported
Glutamic Acid Hydrochloride	Glutamic Acid	Not disclosed on label	Not reported
Papain	Papain	Not disclosed on label	Not reported
Pepsin	Pepsin	Not disclosed on label	Not reported
Pancreatin	Pancreatin	Not disclosed on label	Not reported
Ox Bile extract	Bile	Not disclosed on label	Not reported
Providing at least the following	Header	Not disclosed on label	Not reported
Protease	Proteolytic Enzymes (Proteases)	Not disclosed on label	Not reported
Amylase	Amylase	Not disclosed on label	Not reported
Lipase	Lipase	Not disclosed on label	Not reported
Capsule	capsule	Not disclosed on label	Not reported
Silica	Silicon	Not disclosed on label	Not reported
Stearic Acid	Stearic Acid	Not disclosed on label	Not reported
Vegetable Stearate	Magnesium stearate	Not disclosed on label	Not reported
Maltodextrin	Maltodextrin	Not disclosed on label	Not reported

How does DuoZyme compare?

Compare with

Ingredients listed on each label, against the non-nutrient/non-botanical category average of 6.9. Data from the NIH DSLD.

DuoZyme15

1 Andro Stenelone9

Non-Nutrient/Non-Botanical average6.9

DuoZyme lists 6 ingredients more than 1 Andro Stenelone. That is 8 above the non-nutrient/non-botanical average.

What the Label Data Shows

According to NIH DSLD label rows, DuoZyme sits in the top 26% of products with a countable formula by declared ingredient count.

DuoZyme is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a non-nutrient/non-botanical supplement built from 15 ingredients from Karuna, sold in capsule form. These ingredients span 9 nutrient categories, enzyme, other, non-nutrient/non-botanical, amino acid, and 5 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 15-ingredient formula, 15 of 15 do not carry a reported percentage Daily Value in the source record. That missing field does not establish whether an FDA reference value exists.

A product's market status is worth checking before relying on this label. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2013-08-23. On-market products are currently being distributed in the United States, though the DSLD does not verify the accuracy of label claims or evaluate safety or efficacy.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for DuoZyme: ingredients, % Daily Value, market status, brand · 2026 Accessed 2026-08-14 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nationwide supplements with similar label profiles

Two DSLD-derived peer sets for DuoZyme, both outside the Karuna brand so the neighborhoods are not catalog containment (the same-type Nearby block above stays type-local).

Similar ingredient count

Nearest cross-brand formulas by declared ingredient count (15 here).

Spectra 303-T · Integrative Therapeutics 15 ing. NF Formulas Spectra 303-T · Integrative Therapeutics 15 ing. Vitaline CoQ10 100 mg With Vitamin E Orange Creme Flavor · Integrative Therapeutics 15 ing. Vitaline CoQ10 100 mg Natural CoQ10 Tropical Fruit Flavor · Integrative Therapeutics 15 ing. PMS Formula With Indolplex · Integrative Therapeutics 15 ing. Phytostan · Integrative Therapeutics 15 ing. Best Fully Active B Complex · Doctor's Best 15 ing. Physicians' Protein Premium Quality Whey Mild Vanilla Flavor · Integrative Therapeutics 15 ing.

Similar Capsule peers

Nearest same-form formulas from other brands.

Plant Enzymes · Innate Response Formulas 15 ing. Super Immuno-Tone · Integrative Therapeutics 15 ing. Multi-B Complex · Integrative Therapeutics 15 ing. EHB · Integrative Therapeutics 15 ing. Deluxe Scavengers With CoQ10 · Metabolic Maintenance 15 ing. Cyto-Redoxin · Integrative Therapeutics 15 ing. Menopause Formula · Vitamer Laboratories 15 ing. Synergistic Iron 25 mg · Quest 15 ing.

Ingredient Breakdown by Category

enzyme

Papain, Pepsin, Protease, +2 more

other

Providing at least the following, Capsule, Vegetable Stearate

non-nutrient/non-botanical

Betaine HCl

amino acid

Glutamic Acid Hydrochloride

blend

Pancreatin

animal part or source

Ox Bile extract

mineral

Silica

fatty acid

Stearic Acid

complex carbohydrate

Maltodextrin

Daily Value Coverage

Above 100% DV

Below 100% DV

%DV not reported in source

Frequently Asked Questions

What ingredients are in DuoZyme? ▼

DuoZyme contains 15 ingredients. By declared ingredient count it sits in the top 26% of DSLD products PlainVitamins places. Ingredients span 9 categories: enzyme, other, non-nutrient/non-botanical, amino acid, blend, animal part or source, mineral, fatty acid, complex carbohydrate.

Who manufactures DuoZyme? ▼

DuoZyme is currently manufactured by Karuna. It is classified as a Non-Nutrient/Non-Botanical supplement in capsule form.

Is DuoZyme still available for purchase? ▼

Yes, DuoZyme is currently listed as on-market in the NIH DSLD database.

What is the serving size of DuoZyme? ▼

The serving size is not specified.

What type of supplement is DuoZyme? ▼

DuoZyme is classified as a "Non-Nutrient/Non-Botanical" supplement in the NIH database. This category includes products primarily composed of non-nutrient/non-botanical ingredients. DSLD sorts every supplement into one of 9 categories overall: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, or Other Combinations.

Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Read our methodology , how this data is sourced, computed, and verified.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.