enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 19 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Mayhem Fruit Punch FrenzyMutantin a blend
- Mdrive MultiDreamBrands · off the marketin a blend
- Mega Vita PackWonder Laboratories50 mg
- Mega Vita-MinDC50 mg
- Mega+ MultivitaminFeel Great Vitamin Co.in a blend
- Mega-PolyzymeInterPlexusin a blend
- Mega-ZymeEnzymatic Therapy · off the market50 mg
- Mega-ZymeNature's Way · off the market50 mg
- Mega-Zyme Pancreatic & Systemic EnzymesNature's Way50 mg
- Mega-Zyme Systemic EnzymesEnzymatic Therapy · off the market50 mg
- Megazyme ForteBiophixin a blend
- Memory HealthEmerald Laboratories · off the marketin a blend
- Memory HealthEmerald Labsin a blend
- MenGarden of Life Vitamin Codein a blend
- Men'sGNC Ultra Mega Green · off the marketin a blend
- Men's 45+ MultiVSN Vital Strength Nutrition · off the market5 mg
- Men's 45+ MultiVitaCeutical Labsin a blend
- Men's 45+ MultiVitamer Laboratoriesin a blend
- Men's 50+ Multi-VitaminUltamins · off the marketin a blend
- Men's 50+ Multi-VitaminCalifornia Gold Nutrition Ultaminsin a blend
- Men's GreensInnate Response Formulasin a blend
- Men's Greens Professional Strength GreensBioSan Laboratoriesin a blend
- Men's Multi 45 Plus Daily EssentialsSeniorLife Healthin a blend
- Men's Multi-VitaminUltamins · off the marketin a blend
- Men's MultivitaminGNC Earth Genius · off the marketin a blend
- Men's MultivitaminDivine Bountyin a blend
- Men's MultivitaminCalifornia Gold Nutrition Ultaminsin a blend
- Men's Multivitamins & MineralsRise-N-Shinein a blend
- Men's Nutra PacksNature's Plus · off the market32.5 mg
- Men's OneBluebonnet · off the marketin a blend
- Men's OneRainbow Lightin a blend
- Men's One 40+Bluebonnetin a blend
- MenoSolve Plus Probiotics Original Mint FlavorGreens First Femalein a blend
- Men’s One 50+Rainbow Lightin a blend
- MetabocoreALLMAX2 mg
- MetabolicZymeAllergy Research Group60 mg
- Milk Thistle SportGNC Herbal Plus Formulaanother unit
- Milk Thistle SportGNC Herbal Plusin a blend
- Mini-Tabs No IronNature's Plus Source of Life · off the market30 mg
- Mini-Tabs No IronNaturesPlus Source of Life30 mg
- Miracle EssentialsNature's Plus · off the marketin a blend
- MoabMuscle Warfare · off the marketin a blend
- More Than A Greens Nutritional Powder With Advanced ProbioticsAmerican Healthin a blend
- More Than A Multiple Iron-Free/Vegetarian FormulaAmerican Health8.25 mg
- More Than A Multiple Multivitamin For MenAmerican Health8.25 mg
- More Than A Multiple Multivitamin For WomenAmerican Health8.25 mg
- More Than A Multiple Multivitamin FormulaAmerican Health8.25 mg
- Mucopolysaccharide ConcentrateCardiovascular Research50 mg
- MultiAmvilabin a blend
- Multi and Mineral without IronSwanson · off the market30 mg