Mega-Zyme Pancreatic & Systemic Enzymes
by Nature's Way · tablet or pill · 200 tablets
- On the market (NIH)
- UPC 7 63948 04250 0
- DSLD label 332937
- Serving 2 tablets
- 100 servings
Mega-Zyme Pancreatic & Systemic Enzymes by Nature's Way lists 9 ingredients, 6 with an amount per serving of 2 tablets, such as 75 mg of trypsin, 50 mg of papain, 16 mg of bromelain and 10 mg of amylase; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on August 22, 2025.
What is in Mega-Zyme Pancreatic & Systemic Enzymes?
Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Pancreatic Enzymes | 361 mg | ||
| Amylase81,250 USP, USP units of activity | in the blend, no amount given | ||
| Protease81,250 USP, USP units of activity | in the blend, no amount given | ||
| Lipase6,500 USP, USP units of activity | in the blend, no amount given | ||
| Trypsin | 75 mg | 30% of 77 products listing trypsin give more (median 75 mg). Per day at the most servings: 225 mg. | |
| Papain | 50 mg | Higher than 55% of 607 products listing papain (median 40 mg). Per day at the most servings: 150 mg. | |
| Bromelain | 16 mg | 83% of 1,337 products listing bromelain give more (median 50 mg). Per day at the most servings: 48 mg. | |
| Amylase | 10 mg | 51% of 326 products listing amylase give more (median 14 mg). Per day at the most servings: 30 mg. | |
| Lipase | 10 mg | 45% of 366 products listing lipase give more (median 10 mg). Per day at the most servings: 30 mg. | |
| Chymotrypsin | 2 mg | 63% of 49 products listing chymotrypsin give more (median 3 mg). Per day at the most servings: 6 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 332937 (entered August 22, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 3 ingredients sit inside a blend, so their amounts cannot be compared.
The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
6 products list the very same ingredients; the nearest amounts come first.
- Mega-ZymeNature's Way · off the market same ingredients
- Bio-ZymeIntegrative Therapeutics same ingredients
- Proteolytic EnzymesWonder Laboratories same ingredients
- Enzyme Formula Proteolytic EnzymesDr. Sierra's Naturals same ingredients
- Proteo-ZymeDC same ingredients
- ProteozymeDC same ingredients
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Recommendation: To support digestion, adults take 2 tablets up to three times a day, before each meal. To relieve occasional muscle soreness and discomfort due to overexertion and exercise, take 2 tablets three times a day between meals.
- Warnings
- Keep out of reach of children.
- Safety sealed with inner seal. Do not use if seal is broken or missing.
- Not formulated for children.
- Caution: If you are pregnant, nursing, have diabetes or if you are taking any medications, consult a healthcare professional before use.
- Contains milk and sulfites.
- Allergens and what it does not contain
- Contains no artificial colors.
- Storage
- Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
Source: label statements in DSLD label 332937.
What else is on the label?
Other ingredients: Cellulose, Potassium Bicarbonate, Lactose Monohydrate, Stearic Acid, Hypromellose, Sodium Croscarmellose, Magnesium Stearate, Glycerin, Silica.
How many labels does Mega-Zyme Pancreatic & Systemic Enzymes have?
2 labels are on file under this name since March 25, 2025: other sizes, label designs and reformulations. The current one leads this page.
- Label 332937 (current) Entered August 22, 2025 · on the market · 200 tablets · UPC 7 63948 04250 0
- Label 327997 Entered March 25, 2025 · on the market · 100 tablets · UPC 7 63948 04251 7
DSLD also links this label to: Mega-Zyme (image difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (image difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (image difference, same product), Mega-Zyme (package size difference, same product).
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Nature's Way Brands, LLC (manufacturer), Green Bay, WI. All Nature's Way products.