Mega-Zyme Systemic Enzymes
by Enzymatic Therapy · tablet or pill · 100 tablets
- Off the market since February 2017 (NIH)
- UPC 7 63948 04251 7
- DSLD label 39150
- Serving 2 tablets
- 50 servings
Mega-Zyme Systemic Enzymes by Enzymatic Therapy lists 10 ingredients, 10 with an amount per serving of 2 tablets, such as 75 mg of trypsin, 50 mg of papain, 16 mg of bromelain and 10 mg of amylase. Its current label entered the NIH Dietary Supplement Label Database on November 25, 2014.
What is in Mega-Zyme Systemic Enzymes?
Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Pancreatic EnzymesPancreatic Enzymes Note: (10X) (USP units of activity) | 325 mg | ||
| Protease | 81,250 USP Units | ||
| Amylase | 81,250 USP Units | ||
| Lipase | 6,500 USP Units | ||
| Trypsin | 75 mg | 30% of 77 products listing trypsin give more (median 75 mg). Per day at the most servings: 225 mg. | |
| Papain | 50 mg | Higher than 55% of 607 products listing papain (median 40 mg). Per day at the most servings: 150 mg. | |
| BromelainBromelain Note: 2,400 G.D.U./g | 16 mg | 83% of 1,337 products listing bromelain give more (median 50 mg). Per day at the most servings: 48 mg. | |
| Amylase | 10 mg | 51% of 326 products listing amylase give more (median 14 mg). Per day at the most servings: 30 mg. | |
| Lipase | 10 mg | 45% of 366 products listing lipase give more (median 10 mg). Per day at the most servings: 30 mg. | |
| Lysozymeas Egg | 10 mg | ||
| Chymotrypsin | 2 mg | 63% of 49 products listing chymotrypsin give more (median 3 mg). Per day at the most servings: 6 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 39150 (entered November 25, 2014), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.
The NIH database records 2 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
2 products list the very same ingredients; the nearest amounts come first.
- Mega-ZymeEnzymatic Therapy · off the market same ingredients
- Wholezyme UltraWhole Foods Market same ingredients
- Proteolytic EnzymesWonder Laboratories 7 shared, 80% alike
- Enzyme Formula Proteolytic EnzymesDr. Sierra's Naturals 7 shared, 80% alike
- Proteo-ZymeDC 7 shared, 80% alike
- ProteozymeDC 7 shared, 80% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Recommendations: To relieve muscle soreness and discomfort due to overexertion and exercise, take two tablets two to three times a day between meals. To support optimal digestion, take two tablets before each meal.
- Warnings
- This product is not intended for children.
- If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use.
- Allergens and what it does not contain
- Gluten-Free
Source: label statements in DSLD label 39150.
What else is on the label?
Other ingredients: Cellulose, Potassium Bicarbonate, Modified Cellulose, modified Cellulose Gum, Magnesium Stearate, Silicon Dioxide, Soy Lecithin, Carnauba Wax.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Enzymatic Therapy(R).
How many labels does Mega-Zyme Systemic Enzymes have?
4 labels are on file under this name since September 25, 2013: other sizes, label designs and reformulations. The current one leads this page.
- Label 39150 (current) Entered November 25, 2014 · off the market February 14, 2017 · 100 tablets · UPC 7 63948 04251 7
- Label 39149 Entered November 25, 2014 · off the market August 11, 2023 · 200 tablets · UPC 7 63948 04250 0
- Label 25307 Entered September 25, 2013 · off the market October 15, 2014 · 200 tablets · UPC 7 63948 04250 0
- Label 25306 Entered September 25, 2013 · off the market October 15, 2014 · 100 tablets · UPC 7 63948 04251 7
DSLD also links this label to: Mega-Zyme (package size difference, same product), Mega-Zyme (image difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (package size difference, same product), Mega-Zyme (image difference, same product), Mega-Zyme (package size difference, same product).
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Enzymatic Therapy, LLC (manufacturer), Green Bay, WI. All Enzymatic Therapy products.