enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 32 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Ultimate Digestive EnzymesNatural Goal · off the market50 mg
- Ultimate EnzymesGlobal Healingin a blend
- Ultimate Health ComplexBurbank Glendale Chiropractic2 mg
- Ultimate Man GoldThe Vitamin Shoppe25 mg
- Ultimate Men's Daily PackBurton Nutritionin a blend
- Ultimate OptimizeBeachbody Ultimate · off the marketin a blend
- Ultimate Shake Natural Chocolate FlavorRenew Life Skinny Gutin a blend
- Ultimate Shake Natural Vanilla FlavorRenew Life Skinny Gut · off the marketin a blend
- Ultimate Woman GoldThe Vitamin Shoppe25 mg
- Ultimate Woman Gold No IronThe Vitamin Shoppe25 mg
- Ultra ActiZyme With ActivessenceNature's Plus · off the market50 mg
- Ultra Digestive EnzymesMason Natural50 mg
- Ultra EnzymeNew Sun2 mg
- Ultra EnzymesChemical Free Bodyin a blend
- Ultra GenicDouglas Laboratories10 mg
- Ultra Hair Thick-Shake French VanillaNature's Plus · off the market50 mg
- Ultra Inf-Zyme ForteAB American Biologicsin a blend
- Ultra Juice Green PowderNatures Plusin a blend
- Ultra Man Digestive ComplexVitamin Worldanother unit
- Ultra Man SportVitamin Worldin a blend
- Ultra Mega Green Men'sGNC SuperFoodsin a blend
- Ultra Mega Green Men's 50 PlusGNC Ultra Mega Green · off the marketin a blend
- Ultra Mega Green Men's MultivitaminGNC SuperFoodsin a blend
- Ultra Mega Green Men's SportGNC Ultra Mega Green · off the marketin a blend
- Ultra Mega Green Women'sGNC SuperFoodsin a blend
- Ultra Mega Green Women's 50 PlusGNC Ultra Mega Green · off the marketin a blend
- Ultra Mega Green Women's ActiveGNC SuperFoodsin a blend
- Ultra Mega Green Women's MultivitaminGNC Ultra Mega Green · off the marketin a blend
- Ultra Mega Green Women's MultivitaminGNC SuperFoodsin a blend
- Ultra MultiAltrum · off the marketin a blend
- Ultra Multi with IronAltrumin a blend
- Ultra Multi with-out IronAltrumin a blend
- Ultra Multiple VitaminNew Sun25 mg
- Ultra PreventiveDouglas Laboratories50 mg
- Ultra Preventive 2000 Series C.V. Support FormulaDouglas Laboratories · off the marketin a blend
- Ultra Preventive 2000 Series DGST Support FormulaDouglas Laboratories · off the marketin a blend
- Ultra Preventive XDouglas Laboratories100 mg
- Ultra Source of LifeNature's Plus · off the marketin a blend
- Ultra Source of Life Mini-TabsNatures Plus · off the marketin a blend
- Ultra Source of Life No IronNatures Plusin a blend
- Ultra Supreme Greens & Fruits Powder BlendCalifornia Academy of Health · off the marketin a blend
- Ultra ToxDouglas Laboratoriesin a blend
- Ultra Veggie EnzymesVitabasein a blend
- Ultra VitalitySteele Spirit · off the marketin a blend
- Ultra-ZymeNatures Plus65 mg
- Ultra-ZymesHealthy Choice Naturalsin a blend
- Uni-ViteUniversal · off the marketin a blend
- Uni-ViteUniversal Nutritionin a blend
- Universal Food-ZymeNature's Plus · off the market50 mg
- Universal Power Protein Chocolate FlavorUniversal5 mg