PlainVitamins

enzyme

Papain supplements

Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).

Products listing it
1,770607 print an amount; 1,107 list it inside a blend without an amount
Median per serving
40 mgmiddle half 20 mg to 75 mg

How much papain do supplements contain?

The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).

Products by amount of papain per serving

607 products, log scale; extreme 0.2% at each end left out of the drawing.

Papain: products by amount per serving0.3 mg3 mg30 mg300 mg
Papain: products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg
Papain: products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
Papain: products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
Papain: products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
The amounts printed most often
Amount per servingProductsFor example
50 mg84 Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories)
30 mg65 Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories)
100 mg57 Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories)
25 mg56 Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase)
20 mg34 V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins)
2 mg25 High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont)
5 mg22 Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West)
45 mg22 Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance)
10 mg19 V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation)
200 mg19 Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories)

Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).

Which products list the most papain?

On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).

Have the amounts changed over the years?

Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.

Median papain per serving by the year the label entered DSLD (years with 20+ products)
YearProductsMedian per serving
20124348 mg
20137932.5 mg
20142037.5 mg
20153150 mg
20164125 mg
20172630 mg
20182330 mg
20192930 mg
20205145 mg
20215130 mg
20225850 mg
20234230 mg
20245730 mg
20254550 mg

Source: DSLD label entry dates and amounts, current labels.

In which products and brands?

Products listing papain by DSLD product type

Papain by product typeOther Combinations495Non-Nutrient/Non-Botanical106Botanical with Nutrients5Vitamin1
Papain by product typeOther Combinations495Non-Nutrient/Non-Botanical106Botanical with Nutrients5Vitamin1
Papain by product typeOther Combinations495Non-Nutrient/Non-Botanical106Botanical with Nutrients5Vitamin1
Papain by product typeOther Combinations495Non-Nutrient/Non-Botanical106Botanical with Nutrients5Vitamin1
Papain by product typeOther Combinations495Non-Nutrient/Non-Botanical106Botanical with Nutrients5Vitamin1

Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).

Every product listing papain

1,770 products, A to Z by name (page 31 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.

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