Supreme 18 Digestive Enzymes
by Rise-N-Shine · capsule · 60 capsules
- Off the market since December 2023 (NIH)
- UPC 8 99130 00126 7
- DSLD label 70506
- Serving 1 to 2 vegetable capsules; amounts per 2 vegetable capsules
- 30 servings
Supreme 18 Digestive Enzymes by Rise-N-Shine lists 18 ingredients; 14 give their count of live cultures or enzyme activity instead of a weight; 4 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on February 24, 2017.
What is in Supreme 18 Digestive Enzymes?
Each row as the label prints it, per serving of 2 vegetable capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Protease I | Protease I Note: 40,000 HUT | ||
| Protease II | Protease II Note: 8,000 HUT | ||
| AspergillopepsinAspergillopepsin Note: 200 SAPU | no amount given | ||
| Amylase | Amylase Note: 10,000 DU | ||
| Lipase | Lipase Note: 3,000 FIP | ||
| Cellulase | Cellulase Note: 1,000 CU | ||
| Glucoamylase | Glucoamylase Note: 100 AGU | ||
| Invertase | Invertase Note: 400 SU | ||
| Alpha-GalactosidaseAlpha Galactosidase Note: 100 GAlU | no amount given | ||
| Beta-Glucanase | Beta Glucanase Note: 130 BGU | ||
| PectinasePectinase Note: 33.8 PGU | no amount given | ||
| Xylanase | Xylanase Note: 500 XU | ||
| PhytasePhytase Note: 20 FTU | no amount given | ||
| Hemicellulase | Hemicellulase Note: 2,000 HCU | ||
| Lactase | Lactase Note: 1,000 ALU | ||
| Bromelain | Bromelain Note: 1,000,000 PU | ||
| Papain | Papain Note: 1,000,000 PU | ||
| Peptidase | Peptidase Note: 320 DPPIV |
Source: NIH ODS Dietary Supplement Label Database, label 70506 (entered February 24, 2017), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 18 ingredients sit inside a blend, so their amounts cannot be compared.
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
6 products list the very same ingredients; the nearest amounts come first.
- Biozyme Digestive EnzymesBioGanix · off the market same ingredients
- ColezymeNutrients for Health same ingredients
- Ultra-ZymesHealthy Choice Naturals same ingredients
- Gastric Acid DefenseDrFormulas same ingredients
- Digestive EnyzmesDrFormulas same ingredients
- DigestEzyNutracraft same ingredients
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Suggested Use: 1 to 2 capsules at the beginning of each meal as a dietary supplement, or as directed by a healthcare professional. Do not exceed six capsules daily.
- Do not use if safety seal is damaged or missing.
- Warnings
- Caution: Do not exceed recommended dose.
- Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
- This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.
- Keep out of reach of children.
- Allergen warning: Contains dairy, soy and wheat (from a fermentation process including dairy, soy and wheat).
Source: label statements in DSLD label 70506.
What else is on the label?
Other ingredients: Maltodextrin, Vegetable Capsule, Medium Chain Triglycerides.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Good Manufacturing Practice Quality Assured Sourced from a GMP Certified Facility.
How many labels does Supreme 18 Digestive Enzymes have?
One label is on file, entered on February 24, 2017.
- Label 70506 (current) Entered February 24, 2017 · off the market December 13, 2023 · 60 capsules · UPC 8 99130 00126 7
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Rise-N-Shine, LLC (distributor), Sparta, NJ. All Rise-N-Shine products.