enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 5 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Brain Cell Respirator PlusBioactive Nutritional10 mg
- Brawn Chocolate Cake ShakeMagnumin a blend
- Brawn Vanilla Ice Cream DreamMagnumin a blend
- Break it DownOrain a blend
- Break it Down. Organic PineappleOrain a blend
- Bromelain Papain +Genestra Brands62.5 mg
- Bromelain PlusBiotics Research Corporation10 mg
- Bromelain Plus CLABiotics Research Corporation10 mg
- Bromelain+PapainHerbadiet120 mg
- Bromelain-Papain ComplexMBi Nutraceuticals130 mg
- BromezymeProgressive Professional from Progressive Laboratories100 mg
- C.V. Support FormulaDouglas Laboratoriesin a blend
- Calm BowelsDr. Gumman’s Integrativein a blend
- Calm FlameDr. Gumman’s Integrativein a blend
- Calm NatureHoltraCeuticalsanother unit
- Candipak Forte Nutritional Support SystemDouglas Laboratories · off the market5 mg
- CapraFlexMt. Capra · off the marketin a blend
- CapraFlexDoctor's Choice Naturallyin a blend
- CapraFlex ProMt. Caprain a blend
- CapraZymeMt. Capra · off the marketin a blend
- CapraZymeDoctor's Choice Naturallyin a blend
- Caprylic Acid ComplexFoster Regal100 mg
- Caprylic Acid ComplexWonder Laboratories100 mg
- Caprylic Acid ComplexDC100 mg
- Cardio ClearProgressive Professional from Progressive Laboratories10 mg
- Cardio FlowPL Progressive Laboratories · off the market10 mg
- Cardio FlowProgressive Professional from Progressive Laboratories10 mg
- Cardio HealthEmerald Laboratories · off the marketin a blend
- Cardio VitalzymWorld Nutritionin a blend
- Cardio-Lyph ChelateNutri-West5 mg
- Cardiovascular Health PackDouglas Laboratoriesin a blend
- Cartilage+DaVinci Laboratories of Vermont30 mg
- Catie's Whole Plant Food GreensCatie'sin a blend
- CDC ForteGenestra Brands25 mg
- Chewable Maxi Digest Natural Fruit FlavorMaxi Health100 mg
- Chewable Multi-Vitamin with Probiotics & Enzymes for ChildrenVitablesin a blend
- Chewable Natural Papaya Natural Tropical Fruit FlavorVitaCeutical Labs · off the market200 mg
- Chewable Natural Papaya Natural Tropical Fruit FlavorVitamer Laboratories · off the market200 mg
- Chewable Natural Papaya Natural Tropical Fruit FlavorVillage Vitality · off the market200 mg
- Chewable Natural Papaya Natural Tropical Fruit FlavorNatural Nutra200 mg
- Chewable Natural Papaya Plus Enzymes Natural Tropical Fruit FlavorVSN Vital Strength Nutrition · off the market200 mg
- Chewable Natural Papaya plus Plant Enzymes Tropical Fruit FlavorWoodstock Vitamins200 mg
- Chewable Natural Papaya Tropical Fruit FlavorWoodstock Vitamins200 mg
- Chewable NutraSecNature's Plus · off the market35 mg
- Chewable NutraSec PeppermintNaturesPlus35 mg
- Chewable Nutri-Zyme Natural PeppermintNatures Plus70 mg
- Chewable Original Papaya EnzymeAmerican Health45 mg
- Chewable PapayaBio-Nutrient20 mg
- Chewable PapayaViva Vitamins60 mg
- Chewable Papaya EnzymeSundown Naturalist15 mg