enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 4 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- ArteriozymeEnergiquein a blend
- Arthro-SynDouglas Laboratories25 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Assist Full SpectrumBody Ecologyin a blend
- Assist SIBody Ecologyin a blend
- Assure Detox Straw-Mango FlavorTotal Eclipsein a blend
- Assure Detox Tropical FlavorTotal Eclipsein a blend
- Aved-Eze MultiAnabolic Laboratories · off the market20 mg
- AxionXyngular12.5 mg
- BalanceLegionin a blend
- Basic 4 Travel PakWachters' · off the marketin a blend
- Basics Plus With CopperDouglas Laboratories100 mg
- Bean & Vegetable Gas ReliefProCaps Laboratoriesin a blend
- Begin Daily GI PrimerNutrilitein a blend
- Belly TonIQ Watermelon Kiwi StrawberryGNC Earth Genius · off the marketin a blend
- Best Digestive Enzymes All VegetarianDoctor's Best · off the marketanother unit
- Best Proteolytic EnzymesDoctor's Best · off the marketin a blend
- Beta-GestNeoLife Nutritionals30 mg
- Beta-ZymeNeoLife Nutritionals170 mg
- Betaine HCLGood State · off the market150 mg
- Betaine HCLRemedys Nutritionin a blend
- Betaine HCL 650 mgGood State150 mg
- Betaine HCl PlusDouglas Cooper Co.in a blend
- Betaine Hydrochloride 600 mg With PepsinCountry Life10 mg
- Betaine Hydrochloride With Pepsin 600 mgCountry Life · off the market10 mg
- Betten-AidDr. LaMar's Productsin a blend
- BID MultiSelectMoss Nutrition20 mg
- BID MultiSelect (without Copper, Iron, Vitamin K)Moss Nutrition20 mg
- BilexDouglas Laboratoriesin a blend
- Bio Enzymes Great-Tasting Natural Peppermint FlavoredGenestra Brands10 mg
- Bio Enzymes Natural Peppermint FlavorGenestra Brands · off the market20 mg
- Bio-B12Thorne Research · off the market75 mg
- Bio-Detox PacksBiotics Research Corporation20 mg
- Bio-GestMBi Nutraceuticals60 mg
- Bio-Inflammatory Plus Functional FoodBioGenesis Nutraceuticals · off the market100 mg
- Bio-NaturalviteMBi Nutraceuticals40 mg
- Bio-ProMBi Nutraceuticals5 mg
- Bio-ZymeIntegrative Therapeutics50 mg
- Bio.Revive Digestive +Invivoin a blend
- Bio.Revive Digestive+Invivo · off the marketin a blend
- Biozyme Digestive EnzymesBioGanix · off the marketin a blend
- Blood Pressure HealthEmerald Laboratories · off the marketin a blend
- Blood Pressure HealthEmerald · off the marketin a blend
- Blood Pressure HealthEmerald Labsin a blend
- Blood Sugar HealthEmerald Laboratories · off the marketin a blend
- Blood Sugar HealthEmerald · off the marketin a blend
- Blood Sugar HealthEmerald Labsin a blend
- Blue HeronIntegrative Therapeutics3.7 mg
- Bovine Cartilage PlusBodSmith · off the market30 mg