enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 6 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Chewable Papaya EnzymeNatures Plus · off the market6 mg
- Chewable Papaya Enzyme21st Centuryin a blend
- Chewable Papaya EnzymeNature's Blend60 mg
- Chewable Papaya EnzymeNaturesPlus6 mg
- Chewable Papaya Enzyme Complex Papaya FlavorSpring Valley40 mg
- Chewable Papaya Enzyme with ChlorophyllAmerican Health45 mg
- Chewable Papaya EnzymesNatural Factors · off the marketanother unit
- Chewable Papaya EnzymesLuckyHerbs100 mg
- Chewable Papaya EnzymesNature's Truth · off the market45 mg
- Chewable Papaya EnzymesNOW100 mg
- Chewable Papaya Enzymes With Mint And ChlorophyllNOW · off the market100 mg
- Chewable Papaya PapainPuritan's Pride3.99 mg
- Chewable Papaya Plus Digestive Enzyme Complex Natural Fruit FlavorSwanson Premium Brand · off the market2 mg
- Chewable Papaya Tablets with Papain & BromelainWindmillin a blend
- Chewable Peppermint EnzymeVitaCeutical Labs100 mg
- Chewable Peppermint EnzymeVitamer Laboratories100 mg
- Chewable Peppermint EnzymeNatural Nutra100 mg
- Chewable Pineapple BromelainGood 'N Natural · off the market20 mg
- Chewable Super Papaya Enzyme PlusGood 'N Natural · off the market45 mg
- Chewable Super Papaya Enzyme PlusPuritan's Pride Premium45 mg
- Chewable Super Papaya Enzyme PlusPuritan's Pridein a blend
- Chewable Super Papaya Enzyme PlusAmerican Health45 mg
- Chewables Delicious Tropical Fruit FlavorNatures Plus Source of Life Gold · off the marketin a blend
- Children's Chewable Tummy Zyme Natural Tropical Fruit FlavorNatures Plus Source of Life Animal Parade · off the market15 mg
- Children's Chewable Tummy Zyme Sugar Free Tropical Fruit FlavorNaturesPlus Animal Parade15 mg
- Children's Feed My Brain Fruit Punch FlavorTrace Mineralsin a blend
- Children's Whole Foods PapayazymeNature's Sunshinein a blend
- Chole Health Support With Phytosterol ComplexMartin Avenue Pharmacy50 mg
- Cholesterol HealthEmerald Laboratories · off the marketin a blend
- Cholesterol HealthEmeraldin a blend
- Cholesterol HealthEmerald Labsin a blend
- ClassicRelivin a blend
- Clean & Lean Recovery Shake ChocolateLyfe Fuelin a blend
- Clean & Lean Recovery Shake Vanilla ChaiLyfe Fuelin a blend
- Clinical AntiangiogenesisNatural Clinician100 mg
- Clinical EnzymesNatural Clinician200 mg
- CoEnzymated Adrenal HealthEmerald Laboratories · off the marketin a blend
- CoEnzymated Adrenal HealthEmerald · off the marketin a blend
- CoEnzymated B HealthyEmerald Laboratories · off the marketin a blend
- CoEnzymated B-HealthyEmerald · off the marketin a blend
- CoEnzymated Complete 1-Daily MultiEmerald Laboratories · off the marketin a blend
- CoEnzymated Complete 1-Daily MultiEmeraldin a blend
- CoEnzymated Complete Clinical+Multi 4 DailyEmeraldin a blend
- CoEnzymated Complete Multi Vit-A-MinEmerald Laboratories · off the marketin a blend
- CoEnzymated Complete Premium+Multi 2 DailyEmerald Laboratoriesin a blend
- CoEnzymated High Potency 4-Daily MultiEmerald · off the marketin a blend
- CoEnzymated High Potency Multi Vit-A-MinEmerald Laboratories · off the marketin a blend
- CoEnzymated Men's 1-Daily MultiEmeraldin a blend
- CoEnzymated Men's 45+ 1-Daily MultiEmerald · off the marketin a blend
- CoEnzymated Men's 45+ 4-Daily MultiEmerald · off the marketin a blend