enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 22 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Nutrigen Cranberry AppleMN Morphogen Nutritionin a blend
- Nutrigen Pineapple PunchMorphogen Nutritionin a blend
- Nutritional Management PackDouglas Laboratories48 mg
- NutrizymeAN American Nutriceuticalsin a blend
- OC PackDouglas Laboratories100 mg
- Omega GreensHeartland Products · off the marketin a blend
- Omega-ZymeGarden of Lifein a blend
- Omega-Zyme Digestive Enzyme BlendGarden of Lifeanother unit
- Omega-Zyme Ultra Ultimate Digestive EnzymeGarden of Life · off the marketin a blend
- Omega-Zyme Ultra Ultimate Digestive Enzyme BlendGarden of Lifein a blend
- Omega-Zyme Ultra Ultra Digestive EnzymeGarden of Life · off the marketin a blend
- Omega-Zyme UtraGarden of Life · off the marketanother unit
- One Daily with Lutein & LycopeneThe Vitamin Shoppein a blend
- One for MenBluebonnetin a blend
- Opti-MenON Optimum Nutritionin a blend
- Opti-MenOptimum Nutritionin a blend
- Optimal MultivitaminSeeking Health50 mg
- Optimal Probiotic Complex 50 Billion CFUSupplements Studioin a blend
- OptimenON Optimum Nutritionin a blend
- OptimizeBeachbody Ultimatein a blend
- Orange OxiMega Greens Spearmint FlavorControlled Labsin a blend
- Orange Triad + Greens Orange FlavorControlled Labsin a blend
- Orenda EazeOrenda Internationalin a blend
- Organic Digest +Tropical Fruit FlavorGarden of Life Dr. Formulated Enzymesin a blend
- Organic Digest+ Tropical Fruit FlavorGarden of Life Dr. Formulated Enzymesin a blend
- Organic Fermented Protein & Greens Super Nutrition BlendSoTru · off the marketin a blend
- Organic Fit Chocolate FlavorGarden of Lifein a blend
- Organic Fit Vanilla FlavorGarden of Lifein a blend
- Organic GreensSoTru · off the marketanother unit
- Organic Juce Garden BerryTerra Kaiin a blend
- Organic Protein Chocolate CocoaNature's Food · off the marketin a blend
- Organic Protein Vanilla BeanNature's Food · off the marketin a blend
- Organic Ultra Juice Green PowderNaturesPlusin a blend
- Organic Whole Food B ComplexAmazon Elementsin a blend
- OrganiX PhytoFoodXYMOGEN EP · off the marketin a blend
- Original Chewable Papaya EnzymeNature's Bounty45 mg
- Original Formula UnflavoredAll Onein a blend
- Original Papaya EnzymePuritan's Pride45 mg
- Original Papaya EnzymeRadiance45 mg
- Ortho DigestzymeOrtho Molecular Products100 mg
- Ortho Multi GreensProtocol For Life Balance12.5 mg
- Osteo Bone HealthEmerald Laboratories · off the marketin a blend
- Osteo Bone HealthEmerald · off the marketin a blend
- Osteo Bone HealthEmerald Labsin a blend
- P3 HCL DigestPatient One MediNutritionals · off the market50 mg
- P3 HCL DigestPatient One 1 MediNutritionals · off the market50 mg
- Pack #2, Wobenzym NDouglas Laboratories180 mg
- Pain & Inflammation BlendInnerzymeanother unit
- Pain CareHerbaMein a blend
- Pain XBioGenesis Nutraceuticals · off the market100 mg