enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 23 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Paleo Protein Unflavored and UnsweetenedNatures Plus · off the marketin a blend
- Paleo Protein Unflavored and UnsweetenedNaturesPlus · off the marketin a blend
- Pan-Ox-5Douglas Laboratoriesin a blend
- Pan-VNuMedicain a blend
- Pan-V RxNuMedica · off the marketin a blend
- PankreonGM Germa30 mg
- PapainHerbadiet200 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain ExtractHerbadiet200 mg
- Papain Papaya Enzyme 100 mgSwanson Premium Brand · off the market100 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya CompleteGNC Natural Brandanother unit
- Papaya Complex Natural Peppermint FlavorDC45 mg
- Papaya Complex Natural Peppermint FlavorWonder Laboratories45 mg
- Papaya Digestive Support Pineapple PapayaCountry Life · off the market28 mg
- Papaya Digestive Support Pineapple Papaya FlavorCountry Lifein a blend
- Papaya EnzymeVitabase15 mg
- Papaya EnzymeVitamin World45 mg
- Papaya EnzymeIndiana Botanic Gardens · off the market30 mg
- Papaya EnzymeNatrol40 mg
- Papaya EnzymeBotanic Choice30 mg
- Papaya EnzymeBIOVEA20 mg
- Papaya EnzymeGNC Natural Brand6 mg
- Papaya EnzymePuritan's Pride45 mg
- Papaya Enzyme21st Centuryin a blend
- Papaya Enzyme ChewableNature's Harmony100 mg
- Papaya Enzyme ChewableInnerzymeanother unit
- Papaya Enzyme ChewableCHK Nutritionin a blend
- Papaya Enzyme ChewableMeijer40 mg
- Papaya Enzyme ChewableBIOVEA15 mg
- Papaya Enzyme ChewableRon Teeguarden Nutraceuticals15 mg
- Papaya Enzyme Chewable TabletsIndiana Botanic Gardens · off the market30 mg
- Papaya Enzyme Chewables Natural Pineapple FlavorSolaray2 mg
- Papaya Enzyme Natural Cherry FavorThe Vitamin Shoppein a blend
- Papaya Enzyme With Bromelain & AmylaseWebber Naturals · off the marketanother unit
- Papaya EnzymesNatural Factorsin a blend
- Papaya Enzymes ChewableSunshine Naturals40 mg
- Papaya Ginger Soft ChewsGNC Earth Genius · off the marketin a blend
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Papaya SupremeSwanson Premium Brand · off the market100 mg
- Para ThyrolateProgressive Professional from Progressive Laboratories10 mg
- Para ZymeRenew Lifein a blend
- Para Zyme TargetedRenew Lifein a blend
- Para-RidNature's Secretin a blend
- Parasitab +BioPerineApproved Science · off the market25 mg
- ParasitinVAXAin a blend
- Parazym-ANutri-West5 mg
- ParaZYMERenew Life · off the marketin a blend
- Part 1 Enzyme BlendRenew Life Brenda Watson's Vital Womananother unit