PlainVitamins

Papaya Enzyme

by GNC Natural Brand · tablet or pill · 600 chewable tablets

  • On the market (NIH)
  • UPC 0 48107 06243 9
  • DSLD label 243517
  • Serving 3 to 9 tablets; amounts per 3 tablets
  • 200 servings

Papaya Enzyme by GNC Natural Brand lists 2 ingredients, 2 with an amount per serving of 3 tablets, such as 45 mg of papaya fruit powder and 6 mg of papain, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on February 25, 2021.

What is in Papaya Enzyme?

Each row as the label prints it, per serving of 3 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Papaya Enzyme: Supplement Facts rows against the market (DSLD label 243517, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Total Carbohydrates1.5 g1%Carbohydrate in Papaya Enzyme against 21,979 products1.5 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1.5 g

73% of 21,979 products listing carbohydrate give more (median 3 g).

Total Sugars1.5 gSugar in Papaya Enzyme against 11,807 products1.5 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.1.5 g

68% of 11,807 products listing sugar give more (median 2 g).

Added Sugars1.5 g3%
Papaya fruit powder45 mgPapaya in Papaya Enzyme against 250 products45 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.45 mg

60% of 250 products listing papaya give more (median 50 mg).

PapainPapain Note: 60,000 USP units6 mgPapain in Papaya Enzyme against 607 products6 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.6 mg

89% of 607 products listing papain give more (median 40 mg).

Source: NIH ODS Dietary Supplement Label Database, label 243517 (entered February 25, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Papaya Enzyme's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, chew three to nine tablets daily as desired.
Warnings
Keep out of reach of children.
Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Discontinue use two weeks prior to surgery.
Allergens and what it does not contain
No preservatives, no wheat, gluten free, no soy, no dairy.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 243517.

What else is on the label?

Other ingredients: Sucrose, Dextrose, Maltodextrin, Stearic Acid, Talc, Artificial color, Natural & Artificial Papaya flavor, Protease, Alpha-Amylase, Natural & Artificial Black Cherry flavor, Artificial Fruit flavor, Ethyl Maltol.

How many labels does Papaya Enzyme have?

8 labels are on file under this name since November 25, 2011: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 243517 (current) Entered February 25, 2021 · on the market · 600 chewable tablets · UPC 0 48107 06243 9
  2. Label 214210 Entered February 26, 2020 · on the market · 240 chewable tablets · UPC 0 48107 06242 2
  3. Label 76839 Entered August 22, 2017 · on the market · 600 chewable tablets · UPC 0 48107 06243 9
  4. Label 76838 Entered August 22, 2017 · off the market December 26, 2019 · 240 chewable tablets · UPC 0 48107 06242 2
  5. Label 17792 Entered January 25, 2013 · off the market May 11, 2017 · 600 chewable tablets · UPC 0 48107 06243 9
  6. Label 17789 Entered January 25, 2013 · off the market May 11, 2017 · 240 chewable tablets · UPC 0 48107 06242 2
  7. Label 2258 Entered November 25, 2011 · off the market December 9, 2022 · 90 chewable tablets · UPC 0 48107 06241 5
  8. Label 2257 Entered November 25, 2011 · off the market January 2, 2013 · 600 chewable tablets · UPC 0 48107 06243 9

DSLD also links this label to: Papaya Complete (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names General Nutrition Corporation (distributor), Pittsburgh, PA. All GNC Natural Brand products.

Where next?