PlainVitamins

Papaya Enzyme

by Indiana Botanic Gardens · tablet or pill · 180 tablets

  • Off the market since June 2017 (NIH)
  • UPC 7 03308 46005 6
  • DSLD label 76222
  • Serving 3 tablets
  • 60 servings

Papaya Enzyme by Indiana Botanic Gardens lists 4 ingredients, 4 with an amount per serving of 3 tablets, such as 1.5 mg of alpha-amylase, 30 mg of papain, 3 mg of protease and 15 mg of papaya powder, beside 2 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on July 25, 2017.

What is in Papaya Enzyme?

Each row as the label prints it, per serving of 3 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Papaya Enzyme: Supplement Facts rows against the market (DSLD label 76222, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Total Carbohydrates1 g1%Carbohydrate in Papaya Enzyme against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g). Per day at the most servings: 3 g.

Sugar1 gSugar in Papaya Enzyme against 11,807 products1 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.1 g

69% of 11,807 products listing sugar give more (median 2 g). Per day at the most servings: 3 g.

Alpha-AmylaseAlpha-Amylase Note: 5000 FCC units/gm1.5 mgAmylase in Papaya Enzyme against 326 products1.5 mg per serving; the middle half of products list 5 mg to 50 mg, the median 14 mg.1.5 mg

97% of 326 products listing amylase give more (median 14 mg). Per day at the most servings: 4.5 mg.

PapainPapain Note: (fruit) (2000 USP units/mg)30 mgPapain in Papaya Enzyme against 607 products30 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.30 mg

52% of 607 products listing papain give more (median 40 mg). Per day at the most servings: 90 mg.

ProteaseProtease Note: 5000 FCC units/gm3 mgProteolytic Enzymes (Proteases) in Papaya Enzyme against 327 products3 mg per serving; the middle half of products list 10 mg to 100 mg, the median 30 mg.3 mg

91% of 327 products listing proteolytic enzymes (proteases) give more (median 30 mg). Per day at the most servings: 9 mg.

Papaya powder15 mgPapaya in Papaya Enzyme against 250 products15 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.15 mg

80% of 250 products listing papaya give more (median 50 mg). Per day at the most servings: 45 mg.

Source: NIH ODS Dietary Supplement Label Database, label 76222 (entered July 25, 2017), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 97% of the 326 products that print an amount of amylase list more than its 1.5 mg of alpha-amylase (filed by NIH under amylase) (median 14 mg).
  • 91% of the 327 products that print an amount of proteolytic enzymes (proteases) list more than its 3 mg of proteolytic enzymes (proteases) (median 30 mg).

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: As a dietary supplement, chew three tablets 1-3 times daily.
Best if used by date on bottle.
Warnings
Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.
For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)
Keep out of reach of children
Storage
Store in a dry, cool place.

Source: label statements in DSLD label 76222.

What else is on the label?

Other ingredients: Sucrose, Corn Starch, Maltodextrin, Stearic Acid, Dextrose, Magnesium Silicate, Artificial Flavors, FD&C Yellow #6.

How many labels does Papaya Enzyme have?

One label is on file, entered on July 25, 2017.

  1. Label 76222 (current) Entered July 25, 2017 · off the market June 15, 2017 · 180 tablets · UPC 7 03308 46005 6

DSLD also links this label to: Papaya Enzyme Chewable Tablets (image difference, same product), Papaya Enzyme Chewable Tablets (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Indiana Botanic Gardens, Inc. (distributor), Hobart, IN. All Indiana Botanic Gardens products.

Where next?