non-nutrient/non-botanical

Betaine supplements

Half of the 731 betaine supplements in the NIH label database that print an amount list 250 mg or less per serving; the middle half list 50 mg to 1,250 mg (DSLD version 9.4.0, January 2026). The 38 products whose only supplement ingredient is betaine list a median of 1,000 mg.

Products listing it: 888731 print an amount; 157 list it inside a blend without an amount
Median per serving: 250 mgmiddle half 50 mg to 1,250 mg

How much betaine do supplements contain?

The median product lists 250 mg per serving. One in ten lists 20 mg or less, one in ten 2,500 mg or more. The amount printed most often is 2,500 mg (87 products).

Products by amount of betaine per serving

731 products, log scale; extreme 0.2% at each end left out of the drawing.

The amounts printed most often
Amount per serving	Products	For example
2,500 mg	87	Amplified Muscle Meal Chocolate (GNC Pro Performance AMP); Amplified Muscle Meal Vanilla (GNC Pro Performance AMP); Amplified N.O. Loaded V2 Watermelon (GNC Pro Performance AMP)
500 mg	53	TMG-15 Complex 500 (LifeLink); Pre-Load Creatine Complex Fruit Punch (ON Optimum Nutrition); Clinical Cholesterol/Anti-Homocysteine Support (Natural Clinician)
100 mg	50	Heart Miracle (Century Systems); Clinical Chelation Companion (Natural Clinician); BioFoundation-G (Bioclinic Naturals)
1,500 mg	49	PRE V.2 Raw Unflavored (NutraBio); Post Peach Mango (NutraBio); Clean Post Workout Strawberry Lemonade Flavor (Trace Minerals Research)
1,000 mg	38	Homocysteine Shield (Country Life); Core Fury Electric Lemon-Lime (Core Nutritionals); TMG 1000 mg (The Vitamin Shoppe)
50 mg	35	Vegi Source (Bronson Laboratories); ProtoClear Detoxification Formula (Protocol For Life Balance); ProtoClear Natural Orange Flavor (Protocol For Life Balance)
25 mg	29	Dr. Cutler's Ultimate Gallbladder Support (True Health); Total Thyroid #2 (Nutri-West); Medivin (VPX)
114 mg	27	Ultra Preventive Beta With Copper & Iron (Douglas Laboratories); Ultra Preventive Beta With Copper (Douglas Laboratories); Ultra Preventive III Low Allergenicity (Douglas Laboratories)
10 mg	23	Adult Multi for Men (365 Everyday Value); Women's Ultra Mega Energy & Metabolism Multivitamin (GNC Women's Ultra Mega); Active without Iron (GNC Women's Ultra Mega)
750 mg	22	Pure Betaine Trimethylglycine TMG Powder (HARD RHINO); End Fatigue Daily Energy Enfusion Berry (Integrative Therapeutics); End Fatigue Daily Energy Enfusion Citrus (Integrative Therapeutics)

Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).

Which products list the most betaine?

On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).

Re-Pump Fruit PunchGNC Beyond Raw7,500 mg
Re-Pump WatermelonGNC Beyond Raw7,500 mg
Amplified N.O. Loaded V2 Fruit PunchGNC Pro Performance AMP5,000 mg
Amplified N.O. Loaded V2 Blue RaspberryGNC Pro Performance AMP5,000 mg
Fenris' Fury Frost Giant's Blood Winter CherryValhalla Labs4,000 mg
Gorilla Mode Lightning Blue RaspberryGorilla Mind4,000 mg
Gorilla Mode Nitric Volcano BurstGorilla Mind4,000 mg
Amplified Creatine XXX Power Orange TwistGNC Pro Performance AMP3,750 mg

Have the amounts changed over the years?

Products whose current label entered DSLD in 2012 list a median of 57 mg; those entered in 2025, 1,250 mg.

Median betaine per serving by the year the label entered DSLD (years with 20+ products)
Year	Products	Median per serving
2012	79	57 mg
2013	49	175 mg
2014	35	1,000 mg
2015	43	1,000 mg
2016	26	550 mg
2017	52	125 mg
2018	33	500 mg
2019	28	250 mg
2020	65	750 mg
2021	33	60 mg
2022	48	200 mg
2023	48	425 mg
2024	60	132 mg
2025	122	1,250 mg

Source: DSLD label entry dates and amounts, current labels.

In which products and brands?

Products listing betaine by DSLD product type

Brands listing it most: Douglas Laboratories (67), Country Life (31), JYM Supplement Science (25), GNC Beyond Raw (20), Life Extension (19), GHOST (18), SuperNutrition (13), Kirkman (12), Protocol For Life Balance (11), Allergy Research Group (11).

Every product listing betaine

888 products, A to Z by name (page 16 of 18), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.

TMG 1,000 mgNOW · off the market1,000 mg
TMG 1000 mgThe Vitamin Shoppe1,000 mg
TMG 1000 mgLife Extension · off the market1,000 mg
TMG 1000 MilligramsNutraBio1,000 mg
TMG 175 mg W/Folinic Acid & Methyl B-12Kirkman · off the market175 mg
TMG 175 mg with Folinic Acid & Methyl B12Kirkman175 mg
TMG 500 mgJarrow Formulas500 mg
TMG 500 mgLife Extension1,000 mg
TMG 500 mgSwanson1,000 mg
TMG 500 mgKirkman500 mg
TMG 500 mg W/Folinic Acid & Methyl B-12Kirkman500 mg
TMG 500 mg with Folate & Methyl B-12Kirkman500 mg
TMG 750 mgNutricost750 mg
TMG 750 mgSource Naturals750 mg
TMG BetaineEarthborn Elements960 mg
TMG Betaine - 1,000 mgLuckyVitamin3,000 mg
TMG Betaine - 1,000 mgNOW3,000 mg
TMG Betaine AnhydrousNutraBio1,000 mg
TMG Betaine Anyhdrous UnflavoredMuscle Feast2,200 mg
TMG CrystalsJarrow Formulas650 mg
TMG Liquid Natural Raspberry FlavorKirkman500 mg
TMG Liquid Natural Raspberry FlavoringKirkman500 mg
TMG PowderLife Extension500 mg
TMG Powder (Trimethylglycine)Life Extension500 mg
TMG Powder 3,000 mgNatural Grocers by Vitamin Cottage3,000 mg
TMG TrimethylglycineRenue By Science1,000 mg
TMG Trimethylglycine 1,000 mgSwanson1,000 mg
TMG Trimethylglycine 750 mgSource Naturals750 mg
TMG-15 Complex 500LifeLink500 mg
Torrent Cherry Berry BlastUniversal Nutrition · off the marketin a blend
Total Eyebright-MNutri-Westin a blend
Total Thyroid #2Nutri-West25 mg
Total TMNutri-West10 mg
Training Ground PRE BlueberryEFX Sports2,600 mg
Training Ground PRE Orange MangoEFX Sports2,600 mg
Transfer Factor BasicsAdvanced Medical Labs · off the market375 mg
Tri ZincNutra BioGenesis36 mg
UIltra Skinny MiniNatures Plusin a blend
Ultimate B+C ComplexSolgar15 mg
Ultimate Fat MetabolizerBiochem Sports152 mg
Ultra B ComplexBioGenesis Nutraceuticals · off the market50 mg
Ultra Cardio Support PackDouglas Laboratories57 mg
Ultra CatabolicDouglas Laboratories76 mg
Ultra FemDouglas Laboratories76 mg
Ultra Genesis Without Iron Or CopperBioGenesis Nutraceuticals · off the market250 mg
Ultra Hepa Trope IIAB American Biologics500 mg
Ultra MultiAltrum · off the market60 mg
Ultra Multi with IronAltrum60 mg
Ultra Multi with-out IronAltrum60 mg
Ultra Preventative XPureFormulas · off the market57 mg