A form of folate
Methylfolate (5-MTHF) supplements
2,069 folate products in the NIH label database list folate as methylfolate (5-MTHF) (17% of the 12,112 folate products); their median is 400 mcg of folate per serving, against 400 mcg across all folate products; the 35 whose only supplement ingredient is folate list a median of 1,000 mcg (DSLD version 9.4.0, January 2026).
How does methylfolate (5-MTHF) compare with the other forms?
The median amount of folate per serving in products naming each form; the count in brackets. The amount is the folate the label gives, as printed.
Median folate per serving by form
Source: Supplement Facts rows and their forms, NIH ODS Dietary Supplement Label Database version 9.4.0, current labels.
- Products
- 2,0691,537 on the market
- Median folate per serving
- 400 mcgall folate products: 400 mcg
- Share of folate products
- 17%2,069 of 12,112
What else do these products contain?
| Ingredient | Share of these products | Median here | Median, all products |
|---|---|---|---|
| Vitamin B12 | 89% | 100 mcg | 36 mcg |
| Vitamin B6 | 85% | 10 mg | 6 mg |
| Riboflavin | 74% | 7.5 mg | 4 mg |
| Niacin | 73% | 25 mg | 20 mg |
| Thiamin | 73% | 10 mg | 5 mg |
| Pantothenic Acid (Vitamin B5) | 71% | 25 mg | 12 mg |
| Vitamin C | 70% | 150 mg | 100 mg |
| Biotin | 69% | 250 mcg | 200 mcg |
| Zinc | 65% | 12 mg | 11 mg |
| Vitamin D | 63% | 25 mcg | 15 mcg |
Which products are they?
60 of the 2,069 (on-market products first, the newest label first), ordered by the amount of folate per serving, largest first; an amount that looks like a slip or a compound's weight comes last, marked.
- B12 Methylfolate Select Natural Berry LozengeMoss Nutrition800 mcg
- Daily 1SuperSmart500 mcg
- BotanabolicLVLUP Health500 mcg
- Methyl CompleteNutraMedix400 mcg
- One Daily Superfood Multi-Vitamin No IronParadise Earth's Blend400 mcg
- Permeability SelectMoss Nutrition400 mcg
- Women's Fermented MultivitaminCodeage400 mcg
- B-ComplexParadise Earth's Blend400 mcg
- Complete Plant-Based Protein Delicious Vanilla FlavorLiveGood200 mcg
- ADHD Vitamin SupportBrainchild Nutritionals167 mcg
- Multi NutriPowderBioCare100 mcg
- Adult Multivitamins & MineralsBioCare100 mcg
- 5-MTHF 1 mgThorne
- Active B ComplexCarlson
- ActivNutrients without IronXYMOGEN
- AngiNOX Elite Natural Fruit Punch FlavorXYMOGEN
- B-Complex plus C & ZincFreeda
- Berberine ForceDaVinci Laboratories
- BrainSustain Vanilla DelightXYMOGEN
- C4 Ultimate Hawaiian Punch Fruit Juicy RedCellucor
- C4 Ultimate Shred Creamsicle Orange CreamCellucor
- C4 Ultimate Strength Frozen BombsicleCellucor
- C4 Ultimate Strength WatermelonCellucor
- CelebrateONE 45 with Iron Tropical TwistCelebrate
- Coenzyme B-Complex AdvancedCountry Life
- Dynamic Brain 300 mgStonehenge Health
- EnergyMDPremium Certified
- FITFood Lean Complete French Vanilla Sugar- & Stevia-FreeXYMOGEN
- FocusHost Defense Mushrooms Mycobenefits
- Life Extension Mix Tablets with Extra NiacinLife Extension
- MagSRTJigsaw Health
- Male Fertility SupportWholesome Story
- Max for Women Iron FreeCountry Life
- MedCaps DPOXYMOGEN
- Men's Daily Formula Liposomal Delivery Peach FlavorCodeage Nanofood
- Methyl B-12 5,000 mcgNOW
- Methyl Folate Lozenges 800 mcg Natural Lemon FlavorSolaray
- Mind Boost DaySimple Smart Science
- Mood Food ESXYMOGEN
- Multi-ADEKCelebrate
- Multivitamin Performance Elite MaxCodeage
- Mutli-ADEKCelebrate
- Neuro PowerDr. Gumman’s Integrative20 mcg (possible slip)
- OptiCleanse GHI Creamy Chocolate Sugar-& Stevia-FreeXYMOGEN
- OptiCleanse GHI Sugar-& Stevia-Free ChaiXYMOGEN
- OptiCleanse Plus Creamy Chocolate No Added Sugar, No SteviaXYMOGEN
- Plant-Based MultivitaminLife Extension
- A.m.Thorne
- Active B-ComplexIntegrative Therapeutics
- B-50 ComplexCelebrate
- Bio-Active Complete Multi Vitamin for MenLiveGood
- Caffeine-Free EnergyFizz Mango Peach FlavorArbonne
- CelebrateONE 45 with Iron Midnight CherryCelebrate
- CelebrateONE Stawberry CremeCelebrate
- Coenzyme B-ComplexCountry Life
- Complete Thymic FormulaLogos Nutritionals
- Core Daily 1 for WomenCountry Life
- Core Daily-1 for Men 50+Country Life
- FeelFit Pea Protein Shake Simply1 Coffee FlavorArbonne
- FeelFit Pea Protein Shake Simply1 Strawberry FlavorArbonne
Source: NIH ODS Dietary Supplement Label Database version 9.4.0; the form each label names for its row. Daily Values: the FDA's Daily Value page.
Which brands make them?
Douglas Laboratories (64), Nature's Plus (64), Thorne Research (58), Pure Encapsulations (55), Metagenics (52), NaturesPlus (51), XYMOGEN (47), Thorne (45), ProCaps Laboratories (43), SmartyPants (39).