St. John's Wort 450 mg

by Nature's Way · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 7 63948 08676 4
  • DSLD label 259591
  • Serving 1 tablet

St. John's Wort 450 mg by Nature's Way lists one ingredient: 450 mg of St. John's wort (stem, leaf, flower) extract per serving of 1 tablet. Its current label entered the NIH Dietary Supplement Label Database on January 22, 2022.

What is in St. John's Wort 450 mg?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

St. John's Wort 450 mg: Supplement Facts rows against the market (DSLD label 259591, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
St. John's Wort (stem, leaf, flower) extractas Hypericins450 mgSt. John's Wort in St. John's Wort 450 mg against 338 products450 mg per serving; the middle half of products list 250 mg to 450 mg, the median 300 mg.450 mg

Higher than 69% of 338 products listing St. John's wort (median 300 mg). Per day at the most servings: 900 mg.

Source: NIH ODS Dietary Supplement Label Database, label 259591 (entered January 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Take 1 tablet twice daily.
Warnings
Warning: This product should not be used by pregnant or nursing women, or by individuals who are taking antidepressant medications. Individuals taking other medications should seek the advice of a prescribing physician prior to using this product.
Avoid excessive exposure to UV radiation (e.g., sunlight or tanning) while using the product.
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
Allergens and what it does not contain
Gluten free. No sugar, salt, yeast, wheat, soy, dairy products, or artificial colors, flavors, or preservatives.

Source: label statements in DSLD label 259591.

What else is on the label?

Other ingredients: Cellulose, Sodium Croscarmellose, Stearic Acid, Magnesium Stearate, Silica, Hypromellose, Glycerin, Carnauba wax.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing - Bottled & Tested in the USA.

How many labels does St. John's Wort 450 mg have?

One label is on file, entered on January 22, 2022.

  1. Label 259591 (current) Entered January 22, 2022 · on the market · 60 tablets · UPC 7 63948 08676 4

DSLD also links this label to: St. John's Wort (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Brands, LLC (previously branded Enzymatic Therapy, LLC) (manufacturer), Green Bay, WI. All Nature's Way products.

Where next?