PlainVitamins

MSM with GS-500

by Nature's Way · capsule · 180 capsules

  • On the market (NIH)
  • UPC 7 63948 07550 8
  • DSLD label 259471
  • Serving 1 capsule
  • 180 servings

MSM with GS-500 by Nature's Way lists 3 ingredients, 3 with an amount per serving of 1 capsule, such as 77 mg of chloride, 500 mg of glucosamine sulfate and 250 mg of methylsulfonylmethane, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on January 22, 2022.

What is in MSM with GS-500?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MSM with GS-500: Supplement Facts rows against the market (DSLD label 259471, January 2026 release)
IngredientAmount% DVAmong products listing it
Chlorideas Glucosamine Sulfate77 mg2%Chloride in MSM with GS-500 against 1,476 products77 mg per serving; the middle half of products list 60 mg to 183.5 mg, the median 75 mg.DV 2,300 mgUL 3,600 mg77 mg

Higher than 52% of 1,476 products listing chloride (median 75 mg). Per day at the most servings: 231 mg.

Sodium50 mg2%Sodium in MSM with GS-500 against 14,514 products50 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.50 mg

51% of 14,514 products listing sodium give more (median 55 mg). Per day at the most servings: 150 mg.

Glucosamine Sulfatestabilized500 mgGlucosamine Sulfate in MSM with GS-500 against 875 products0.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.5 g

65% of 875 products listing glucosamine sulfate give more (median 1 g). Per day at the most servings: 1.5 g.

Methylsulfonylmethane250 mgMethylsulfonylmethane in MSM with GS-500 against 1,454 products250 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.250 mg

60% of 1,454 products listing methylsulfonylmethane give more (median 500 mg). Per day at the most servings: 750 mg.

Source: NIH ODS Dietary Supplement Label Database, label 259471 (entered January 22, 2022), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Take 1 capsule up to three times daily.
Warnings
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
If you are pregnant, nursing or taking any medications, consult a healthcare professional before use.
Contains shellfish (shrimp and crab).
Allergens and what it does not contain
Gluten free. No yeast-derived ingredients, wheat, soy, dairy products, or artificial colors, flavors or preservatives.

Source: label statements in DSLD label 259471.

What else is on the label?

Other ingredients: Hypromellose, Magnesium Stearate, Silica.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing - Bottled & Tested in the USA.

How many labels does MSM with GS-500 have?

7 labels are on file under this name since September 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 259471 (current) Entered January 22, 2022 · on the market · 180 capsules · UPC 7 63948 07550 8
  2. Label 184231 Entered January 7, 2019 · on the market · 90 veg capsules · UPC 7 63948 07559 1
  3. Label 184230 Entered January 7, 2019 · off the market September 13, 2021 · 180 veg capsules · UPC 7 63948 07550 8
  4. Label 78144 Entered January 25, 2018 · off the market June 21, 2018 · 180 veg capsules · UPC 7 63948 07550 8
  5. Label 78149 Entered September 21, 2017 · off the market June 21, 2018 · 90 veg capsules · UPC 7 63948 07559 1
  6. Label 25311 Entered September 25, 2013 · off the market May 16, 2017 · 180 capsules · UPC 7 63948 07550 8
  7. Label 25310 Entered September 25, 2013 · off the market May 15, 2017 · 90 capsules · UPC 7 63948 07559 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Brands, LLC (manufacturer), Green Bay, WI. All Nature's Way products.

Where next?