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Vitamin · Supplement ingredient

Vitamin B6

Vitamin B6 is listed on 10,891 U.S. supplement product labels in the NIH DSLD, making it more common than 99% of cataloged ingredients.

10,891
Products
Vitamin
Category
Top 1%
By frequency
NIH
Dosing fact sheet

Vitamin B6 (Pyridoxine) dosing reference

NIH ODS Fact Sheet →
Recommended Dietary Allowance (RDA / AI)
1.3–1.7 mg for adults (varies by age and sex)
Tolerable Upper Intake Level (UL)
100 mg per day for adults
Drug interactions
Reduces effectiveness of levodopa, certain antiseizure drugs. High doses can cause peripheral neuropathy.
Pregnancy & lactation
RDA during pregnancy is 1.9 mg; lactation 2.0 mg.

Statement required by FDA: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed healthcare provider before starting, stopping, or combining any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Source: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

What does the NIH label data show about Vitamin B6?

Vitamin B6 appears as an ingredient in 10,891 dietary supplement product labels cataloged in the NIH Dietary Supplement Label Database (DSLD). The NIH classifies Vitamin B6 within the Vitamin category. That frequency reflects how often manufacturers list Vitamin B6 on submitted labels, both in single-ingredient products focused on this nutrient and in broader multi-ingredient formulas such as multivitamins, specialty blends, and category-spanning formulations. Across this catalog of 10,891 filings, the ingredient appears in products ranging from standalone capsules to combination formulas containing dozens of other components. Counting how many labels declare an ingredient is a useful way to gauge how common it is in the United States supplement market, though it does not indicate efficacy or safety on its own.

When reviewing products that contain Vitamin B6, pay attention to a few label signals. First, the ingredient's amount per serving and any Daily Value (DV) percentage, some nutrients have an FDA reference daily intake (so a DV is shown), while others (many botanicals, amino acids, specialty compounds) do not. Second, the chemical form listed matters: the same common name can refer to several compounds with different absorption or bioavailability profiles, so the exact wording on the label is worth checking. Third, look at what else the product contains, a supplement listing Vitamin B6 alongside many other active ingredients may deliver a smaller amount than a single-ingredient product of the same total size. All of these data points are declared by the manufacturer on the label as filed with the NIH DSLD.

A reminder on scope: the DSLD is a label database, not an approval list. Dietary supplements are regulated in the United States under the Dietary Supplement Health and Education Act (DSHEA) of 1994, which does not require FDA pre-market approval for safety or efficacy. Inclusion of Vitamin B6 on a product label does not imply that the FDA has evaluated claims about the ingredient, verified its potency, or tested the specific bottle you may buy. Some ingredients have well-established research bases, others are far more speculative, and effects can vary by form, dose, and individual health status. This page presents factual label-frequency data and is not medical or nutritional advice, consult a licensed healthcare provider before starting, stopping, or combining supplements, especially if you are pregnant, take prescription medication, or have a medical condition.

How common is Vitamin B6?

Number of supplement labels listing Vitamin B6 vs nearby vitamin ingredients

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026

Products containing Vitamin B6

Meal Replacement Cake Batter
MET-Rx
52 ingredients · Amino acid/Protein
On Market
Meal Replacement Shake Vanilla Flavored
Beachbody Nutritionals
67 ingredients · Multi-Vitamin and Mineral (MVM)
On Market
Medical Prenatal
Perry
21 ingredients · Multi-Vitamin and Mineral (MVM)
On Market
MediClear-SGS Chocolate Flavored
Thorne
63 ingredients · Other Combinations
On Market
MediClear-SGS Vanilla Flavored
Thorne
58 ingredients · Other Combinations
On Market
Mega B-100 Sustained Release
NaturesPlus
21 ingredients · Other Combinations
On Market
Mega B-100 Timed Release
Vitamin World
14 ingredients · Other Combinations
On Market
Mega B-50 Timed Release
Vitamin World
12 ingredients · Other Combinations
On Market
Mega Biotin 5000
Justified Laboratories
15 ingredients · Botanical with Nutrients
On Market
Mega Daily 4 for Women
Nikken Wellness Kenzen
50 ingredients · Other Combinations
On Market
Mega Men 50 Plus
GNC Mega Men
39 ingredients · Other Combinations
On Market
Mega Men Citrus
GNC Mega Men
53 ingredients · Other Combinations
On Market
Mega Men Energy & Metabolism Multivitamin
GNC Mega Men
56 ingredients · Other Combinations
On Market
Mega Men Essentials 50 Plus One Daily
GNC Mega Men
59 ingredients · Other Combinations
On Market
Mega Men Gummy Multivitamin Mixed Berry
GNC Mega Men
28 ingredients · Multi-Vitamin and Mineral (MVM)
On Market
Mega Men Gummy Multivitamin Mixed Berry
GNC Mega Men
24 ingredients · Multi-Vitamin and Mineral (MVM)
On Market
Mega Men Multivitamin
GNC Mega Men
88 ingredients · Other Combinations
On Market
Mega Men Multivitamin
GNC Mega Men
64 ingredients · Other Combinations
On Market
Mega Men Multivitamin
GNC Mega Men
79 ingredients · Other Combinations
On Market
Mega Men Multivitamin
GNC Mega Men
87 ingredients · Other Combinations
On Market
Mega Men Multivitamin
GNC Mega Men
101 ingredients · Other Combinations
On Market
Mega Men Sport
GNC Mega Men
57 ingredients · Other Combinations
On Market
Mega Men Sport
GNC Mega Men
56 ingredients · Other Combinations
On Market
Mega Men Sport
GNC Mega Men
57 ingredients · Other Combinations
On Market
Mega Men Sport (Full Strength)
GNC Pro Performance AMP Advanced Muscle Performance
57 ingredients · Other Combinations
On Market
Mega Men Sport (Full Strength)
GNC Pro Performance AMP
57 ingredients · Other Combinations
On Market
Mega Men Sport Multivitamin
GNC AMP Advanced Muscle Performance
64 ingredients · Other Combinations
On Market
Mega Men Sport Multivitamin
GNC Mega Men
64 ingredients · Other Combinations
On Market
Mega Men Sport Multivitamin
GNC AMP Advanced Muscle Performance
85 ingredients · Other Combinations
On Market
Mega Men Sport Multivitamin
GNC AMP Advanced Muscle Performance
87 ingredients · Other Combinations
On Market
Mega Men Sport Multivitamin
GNC AMP Advanced Muscle Performance
84 ingredients · Other Combinations
On Market
Mega Multi Softcaps
Bronson
45 ingredients · Other Combinations
On Market
Mega Multi Softcaps
Bronson
45 ingredients · Other Combinations
On Market
Mega Multi Vitamin
Indiana Botanic Gardens
45 ingredients · Other Combinations
On Market
Mega Smoothie Booster Unflavored
Probiogen
25 ingredients · Other Combinations
On Market
Mega Vita Gel
Radiance
47 ingredients · Other Combinations
On Market
Mega Vita Gel Iron Free
Vitamin World
36 ingredients · Other Combinations
On Market
Mega Vita Min For Seniors
Vitamin World
41 ingredients · Other Combinations
On Market
Mega Vita Min For Women
Radiance
60 ingredients · Other Combinations
On Market
Mega Vita Woman 50+ High Potency
Vitamin World
49 ingredients · Other Combinations
On Market
Mega Vita-Gel
Vitamin World
46 ingredients · Other Combinations
On Market
Mega Vita-Min
Radiance
55 ingredients · Other Combinations
On Market
Mega Vita-Min Adult Chewable Pineapple Flavored
Vitamin World
35 ingredients · Other Combinations
On Market
Mega Vitamin B-Stress
Solaray
21 ingredients · Vitamin
On Market
Mega Vitamin B-Stress Timed Release
Solaray
20 ingredients · Other Combinations
On Market
Mega-Liposomal B-Complex+ Organic Fruit Flavor
Aurora NutraScience
20 ingredients · Vitamin
On Market
Mega-Stress Sustained Release
NaturesPlus
31 ingredients · Other Combinations
On Market
Mega-Stress Sustained Release
NaturesPlus
31 ingredients · Other Combinations
On Market
Megawatt Pink Lemonade
1st Phorm
32 ingredients · Other Combinations
On Market
Melatonin + 5-HTP Advanced Time Release
Natrol
14 ingredients · Other Combinations
On Market

Nearby Ingredients in Vitamin

Other ingredients in the Vitamin category cataloged in the NIH DSLD. Useful for comparing how common different nutrients are across the US supplement market.

Compare Vitamin B6 vs Vitamin C →

Frequently asked about Vitamin B6

What is the Recommended Dietary Allowance (RDA) for Vitamin B6 (Pyridoxine)?
1.3–1.7 mg for adults (varies by age and sex). The RDA is the average daily intake sufficient to meet the nutrient requirements of nearly all (97–98%) healthy people. Source: NIH Office of Dietary Supplements.
Is there an upper limit for Vitamin B6 (Pyridoxine)?
100 mg per day for adults (Tolerable Upper Intake Level, UL, the maximum daily intake unlikely to cause adverse health effects in the general population).
Does Vitamin B6 (Pyridoxine) interact with medications?
Reduces effectiveness of levodopa, certain antiseizure drugs. High doses can cause peripheral neuropathy. This is a partial list, always discuss supplement use with a pharmacist or prescribing provider.
What about Vitamin B6 (Pyridoxine) during pregnancy or breastfeeding?
RDA during pregnancy is 1.9 mg; lactation 2.0 mg.
How many supplement products contain Vitamin B6?
10,891 supplement product labels in the NIH DSLD currently lists Vitamin B6 as an ingredient. Browse them below.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) · Dosing reference: NIH ODS Vitamin B6 (Pyridoxine) Health Professional Fact Sheet. Regulatory reference: Source: Dietary Supplement Health and Education Act (DSHEA), 1994, 21 U.S.C. § 321(ff).

Disclaimer, Not Medical Advice: Information on this page is based on manufacturer-declared label data and is provided for educational and reference purposes only. It does not constitute medical, nutritional, or health advice. Consult a licensed healthcare provider before starting, stopping, or combining any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. Ingredient figures are computed directly from the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.