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Vitamin · Supplement ingredient

Vitamin B6

Vitamin B6 is listed on 10,891 U.S. supplement product labels in the NIH DSLD, making it more common than 99% of cataloged ingredients.

10,891
Products
Vitamin
Category
Top 1%
By frequency
NIH
Dosing fact sheet

Vitamin B6 (Pyridoxine) dosing reference

NIH ODS Fact Sheet →
Recommended Dietary Allowance (RDA / AI)
1.3–1.7 mg for adults (varies by age and sex)
Tolerable Upper Intake Level (UL)
100 mg per day for adults
Drug interactions
Reduces effectiveness of levodopa, certain antiseizure drugs. High doses can cause peripheral neuropathy.
Pregnancy & lactation
RDA during pregnancy is 1.9 mg; lactation 2.0 mg.

Statement required by FDA: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed healthcare provider before starting, stopping, or combining any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Source: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

What does the NIH label data show about Vitamin B6?

Vitamin B6 appears as an ingredient in 10,891 dietary supplement product labels cataloged in the NIH Dietary Supplement Label Database (DSLD). The NIH classifies Vitamin B6 within the Vitamin category. That frequency reflects how often manufacturers list Vitamin B6 on submitted labels, both in single-ingredient products focused on this nutrient and in broader multi-ingredient formulas such as multivitamins, specialty blends, and category-spanning formulations. Across this catalog of 10,891 filings, the ingredient appears in products ranging from standalone capsules to combination formulas containing dozens of other components. Counting how many labels declare an ingredient is a useful way to gauge how common it is in the United States supplement market, though it does not indicate efficacy or safety on its own.

When reviewing products that contain Vitamin B6, pay attention to a few label signals. First, the ingredient's amount per serving and any Daily Value (DV) percentage, some nutrients have an FDA reference daily intake (so a DV is shown), while others (many botanicals, amino acids, specialty compounds) do not. Second, the chemical form listed matters: the same common name can refer to several compounds with different absorption or bioavailability profiles, so the exact wording on the label is worth checking. Third, look at what else the product contains, a supplement listing Vitamin B6 alongside many other active ingredients may deliver a smaller amount than a single-ingredient product of the same total size. All of these data points are declared by the manufacturer on the label as filed with the NIH DSLD.

A reminder on scope: the DSLD is a label database, not an approval list. Dietary supplements are regulated in the United States under the Dietary Supplement Health and Education Act (DSHEA) of 1994, which does not require FDA pre-market approval for safety or efficacy. Inclusion of Vitamin B6 on a product label does not imply that the FDA has evaluated claims about the ingredient, verified its potency, or tested the specific bottle you may buy. Some ingredients have well-established research bases, others are far more speculative, and effects can vary by form, dose, and individual health status. This page presents factual label-frequency data and is not medical or nutritional advice, consult a licensed healthcare provider before starting, stopping, or combining supplements, especially if you are pregnant, take prescription medication, or have a medical condition.

How common is Vitamin B6?

Number of supplement labels listing Vitamin B6 vs nearby vitamin ingredients

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026

Products containing Vitamin B6

Melatonin + 5-HTP Time Release
Natrol
14 ingredients · Other Combinations
On Market
Melatonin 1 mg
NOW
9 ingredients · Other Combinations
On Market
Melatonin 1 mg
Natrol
8 ingredients · Other Combinations
On Market
Melatonin 1 mg
Natrol
8 ingredients · Other Combinations
On Market
Melatonin 1 mg
NOW
12 ingredients · Other Combinations
On Market
Melatonin 1 mg Chocolate Mint
KAL
12 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 1 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin 10 mg
Eurovital Nutraceuticals
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 10 mg
OL Olympian Labs
8 ingredients · Other Combinations
On Market
Melatonin 10 mg
OL Olympian Labs
8 ingredients · Other Combinations
On Market
Melatonin 10 mg + B6 Natural Cherry
WonderLabs
7 ingredients · Other Combinations
On Market
Melatonin 10 mg Advanced Sleep Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin 2.5 mg Orange Flavor
Source Naturals Sleep Science
7 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 3 mg
Designs for Health
7 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 3 mg
Mason Natural
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 3 mg
Eurovital Nutraceuticals
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin 3 mg
Vitabase
9 ingredients · Other Combinations
On Market
Melatonin 3 mg
Natrol
10 ingredients · Other Combinations
On Market
Melatonin 3 mg
Natrol
8 ingredients · Other Combinations
On Market
Melatonin 3 mg
Natrol
8 ingredients · Other Combinations
On Market
Melatonin 3 mg
Viva Vitamins
7 ingredients · Other Combinations
On Market
Melatonin 3 mg
WholeHealth
9 ingredients · Other Combinations
On Market
Melatonin 3 mg
BIOVEA
8 ingredients · Other Combinations
On Market
Melatonin 3 mg
BIOVEA
8 ingredients · Other Combinations
On Market
Melatonin 3 mg Sustained Release
KAL
7 ingredients · Other Combinations
On Market
Melatonin 3 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin 3 mg with B-6
Meijer Naturals
9 ingredients · Other Combinations
On Market
Melatonin 3 mg With Vitamin B-6
Martin Avenue Pharmacy
7 ingredients · Vitamin
On Market
Melatonin 30 mg Strawberry Flavor
Safrel
12 ingredients · Other Combinations
On Market
Melatonin 5 mg
Natrol
9 ingredients · Other Combinations
On Market
Melatonin 5 mg
Mason Natural
8 ingredients · Other Combinations
On Market
Melatonin 5 mg
Puritan's Pride
8 ingredients · Other Combinations
On Market
Melatonin 5 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin 5.0 mg Peppermint Flavor
Source Naturals Sleep Science
7 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin Advanced 10 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin Advanced 10 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin Advanced 10 mg Time Release
Natrol
10 ingredients · Other Combinations
On Market
Melatonin Peppermint Flavor
NuMedica
9 ingredients · Other Combinations
On Market
Melatonin Plus
Schiff
10 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin Plus
Schiff
10 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin Plus 5 mg
Vitamer Laboratories
6 ingredients · Non-Nutrient/Non-Botanical
On Market
Melatonin Plus 5 mg
Woodstock Vitamins
6 ingredients · Other Combinations
On Market
Melatonin Select 3 mg
Moss Nutrition
5 ingredients · Other Combinations
On Market
Melatonin Spray
Energetix
11 ingredients · Other Combinations
On Market
Melatonin Spray 1 mg
SuperSmart
8 ingredients · Other Combinations
On Market
Melatonin Sublingual 2.5 mg (2,500 mcg) Fruit Flavored
Wonder Laboratories
8 ingredients · Other Combinations
On Market
Melatonin Two Stage Release 1 mg
Vitabase
9 ingredients · Other Combinations
On Market
Memory & Brain with Acetyl L-Carnitine
ProCaps
19 ingredients · Other Combinations
On Market
Memory & Focus 750 mg
Nutra Harmony
17 ingredients · Other Combinations
On Market
Memory & Mental Support
Pathway To Healing
13 ingredients · Other Combinations
On Market

Nearby Ingredients in Vitamin

Other ingredients in the Vitamin category cataloged in the NIH DSLD. Useful for comparing how common different nutrients are across the US supplement market.

Compare Vitamin B6 vs Vitamin C →

Frequently asked about Vitamin B6

What is the Recommended Dietary Allowance (RDA) for Vitamin B6 (Pyridoxine)?
1.3–1.7 mg for adults (varies by age and sex). The RDA is the average daily intake sufficient to meet the nutrient requirements of nearly all (97–98%) healthy people. Source: NIH Office of Dietary Supplements.
Is there an upper limit for Vitamin B6 (Pyridoxine)?
100 mg per day for adults (Tolerable Upper Intake Level, UL, the maximum daily intake unlikely to cause adverse health effects in the general population).
Does Vitamin B6 (Pyridoxine) interact with medications?
Reduces effectiveness of levodopa, certain antiseizure drugs. High doses can cause peripheral neuropathy. This is a partial list, always discuss supplement use with a pharmacist or prescribing provider.
What about Vitamin B6 (Pyridoxine) during pregnancy or breastfeeding?
RDA during pregnancy is 1.9 mg; lactation 2.0 mg.
How many supplement products contain Vitamin B6?
10,891 supplement product labels in the NIH DSLD currently lists Vitamin B6 as an ingredient. Browse them below.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) · Dosing reference: NIH ODS Vitamin B6 (Pyridoxine) Health Professional Fact Sheet. Regulatory reference: Source: Dietary Supplement Health and Education Act (DSHEA), 1994, 21 U.S.C. § 321(ff).

Disclaimer, Not Medical Advice: Information on this page is based on manufacturer-declared label data and is provided for educational and reference purposes only. It does not constitute medical, nutritional, or health advice. Consult a licensed healthcare provider before starting, stopping, or combining any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. Ingredient figures are computed directly from the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.