A form of vitamin B12
Hydroxocobalamin supplements
139 vitamin B12 products in the NIH label database list vitamin B12 as hydroxocobalamin (under 1% of the 14,774 vitamin B12 products); their median is 400 mcg of vitamin B12 per serving, against 36 mcg across all vitamin B12 products; the 23 whose only supplement ingredient is vitamin B12 list a median of 2,000 mcg (DSLD version 9.4.0, January 2026).
How does hydroxocobalamin compare with the other forms?
The median amount of vitamin B12 per serving in products naming each form; the count in brackets. The amount is the vitamin B12 the label gives, as printed.
Median vitamin B12 per serving by form
Source: Supplement Facts rows and their forms, NIH ODS Dietary Supplement Label Database version 9.4.0, current labels.
- Products
- 139113 on the market
- Median vitamin B12 per serving
- 400 mcgall vitamin B12 products: 36 mcg
- Share of vitamin B12 products
- under 1%139 of 14,774
What else do these products contain?
| Ingredient | Share of these products | Median here | Median, all products |
|---|---|---|---|
| Vitamin B6 | 76% | 15 mg | 6 mg |
| Folate | 73% | 400 mcg | 400 mcg |
| Niacin | 64% | 30 mg | 20 mg |
| Pantothenic Acid (Vitamin B5) | 63% | 25 mg | 12 mg |
| Riboflavin | 60% | 10 mg | 4 mg |
| Thiamin | 60% | 17.5 mg | 5 mg |
| Biotin | 56% | 250 mcg | 200 mcg |
| Zinc | 50% | 15 mg | 11 mg |
| Magnesium | 49% | 100 mg | 86 mg |
| Vitamin C | 48% | 180 mg | 100 mg |
Which products are they?
60 of the 139 (on-market products first, the newest label first), ordered by the amount of vitamin B12 per serving, largest first; an amount that looks like a slip or a compound's weight comes last, marked.
- Methylation Complete ProNBX Wellness7,000 mcg
- Vitamin B12 5,000 mcgGlobal Healing5,000 mcg
- B12 MC LiquidDaVinci Laboratories5,000 mcg
- Advanced B-12 Complex 5 mgSource Naturals5,000 mcg
- hydro B12Good State3,000 mcg
- Vitamin B12 3000 mcg Raspberry FlavorAmazon Basics3,000 mcg
- Liposomal B12 Blood Orange FlavorVinco3,000 mcg
- Hydrox-Adeno B12 2,000 mcgSeeking Health2,000 mcg
- Hydroxo B12 2,000 mcgSeeking Health2,000 mcg
- Activated B12 Complex Natural Cherry FlavorSwanson2,000 mcg
- Adenosyl/Hydroxy B12Pure Encapsulations2,000 mcg
- Daily Pure Pack LongevityPure Encapsulations2,000 mcg
- Diabetes Script SupportVinco1,000 mcg
- Liposomal Hydroxy B12NuMedica1,000 mcg
- Hydroxo B12 with Folinic AcidSeeking Health1,000 mcg
- Cholesterol Script SupportVinco1,000 mcg
- Qultured B12Quantum Nutrition Labs1,000 mcg
- PureResponse MultivitaminPure Encapsulations1,000 mcg
- HydroxoCobalamin 1 mg Cherry FlavoredSource Naturals1,000 mcg
- Adenosyl/Hydroxy B12 LiquidPure Encapsulations1,000 mcg
- B6 ComplexPure Encapsulations1,000 mcg
- PureGenomics MultivitaminPure Encapsulations1,000 mcg
- CN-B12 PlusChiroNutraceutical1,000 mcg
- B12-NdPremier Research Labs1,000 mcg
- Hydroxo B-12 LozengeNutri-West1,000 mcg
- MTHFR EndurePhysician Designed1,000 mcg
- Coenzymate B Complex PeppermintSource Naturals870 mcg
- Coenzymate B Complex Orange FlavoredSource Naturals860 mcg
- PureGenomics Ultra MultivitaminPure Encapsulations800 mcg
- PureGenomics B-ComplexPure Encapsulations800 mcg
- Vitamin B12 500 mcg Raspberry FlavorAmazon Basics500 mcg
- HBP Script SupportVinco500 mcg
- SuperFocusAOR Advanced Orthomolecular Research Advanced500 mcg
- Multiplex Complete Wild Berry FlavorNuMedica400 mcg
- Multivitamin & Essential Minerals BerryFight Labs400 mcg
- Daily Essential Nutrients Iron & Copper FreeHardy Nutritionals300 mcg
- Daily Essential Nutrients with added VitamersHardy Nutritionals300 mcg
- Max Energy Bs FermentedQuantum Nutrition Labs263 mcg
- Qultured Max Stress BQuantum Nutrition Labs263 mcg
- Max B-NDPremier Research Labs263 mcg
- Optimal MultivitaminSeeking Health250 mcg
- Multi-Nutrient Support XPureFormulas250 mcg
- Daily Essential Nutrients Powder Strawberry PeachHardy Nutritionals250 mcg
- Skin Hair Nails SupplementKala Health200 mcg
- Optimal Balance For MenHardy Nutritionals168 mcg
- Optimal Prenatal Methyl-FreeSeeking Health150 mcg
- Gynovite PlusOptimox125 mcg
- Androvite for MenOptimox125 mcg
- Behavior Balance-DMG LiquidDaVinci Laboratories100 mcg
- Prenatal Essentials Methyl-FreeSeeking Health100 mcg
- B Complex MFSeeking Health50 mcg
- B ComplexBioCare50 mcg
- MVM-A with AntioxidantsAllergy Research Group30 mcg
- Vitamin B Complex Supplement Adult Gummy Vitamin Natural Strawberry FlavorSpring Valley30 mcg
- MVM-A with AntioxidantsNutriCology30 mcg
- Multivitamin One MFSeeking Health25 mcg
- Liquid Multi Vite Min Natural Lemon-Cardamom FlavorGenestra Brands25 mcg
- BrainAidNutriCology25 mcg
- BrainStormAllergy Research Group25 mcg
- MultivitaminKaged2.4 mcg
Source: NIH ODS Dietary Supplement Label Database version 9.4.0; the form each label names for its row. Daily Values: the FDA's Daily Value page.
Which brands make them?
Seeking Health (12), Douglas Laboratories (11), Perque (10), Pure Encapsulations (9), Hardy Nutritionals (8), Only Natural (6), Optimox (6), Genestra Brands (6), Pharmax (5), Source Naturals (5).