enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 9 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Digestion PlusArbonne Essentials · off the marketin a blend
- Digestion SupportPathway To Healing25 mg
- Digestion SupportNatures Plus AgeLoss · off the marketin a blend
- Digestion SupportNaturesPlus AgeLossin a blend
- DigestiveHighland Laboratoriesin a blend
- Digestive AidSolgar32 mg
- Digestive AideGet At The Roots Weight Loss · off the market32 mg
- Digestive BalanceRoexin a blend
- Digestive CompleteAnabolic Laboratories · off the marketanother unit
- Digestive ComplexMDLogicin a blend
- Digestive EnyzmesDrFormulasin a blend
- Digestive EnzymeNature's Plus · off the market30 mg
- Digestive EnzymeUSANA · off the marketin a blend
- Digestive Enzyme ComplexInnerzymeanother unit
- Digestive Enzyme ComplexIndiana Botanic Gardensin a blend
- Digestive Enzyme ComplexSMNutritionin a blend
- Digestive Enzyme ComplexBIOVEAin a blend
- Digestive Enzyme Complex 104 mgBIOVEA · off the marketin a blend
- Digestive Enzyme Delicious Mixed Berry FlavorNuLife Advanced Bariatricsin a blend
- Digestive Enzyme FormulaGNC Ultra Mega Green · off the marketanother unit
- Digestive Enzyme FormulaPuritan's Pride20 mg
- Digestive Enzyme PlusLongevity Premierin a blend
- Digestive Enzyme Pro BlendOL Olympian Labsin a blend
- Digestive Enzyme Pro BlendJust Ripe Nutritionin a blend
- Digestive Enzyme ProblendiPro Organic Supplements · off the marketin a blend
- Digestive Enzyme Ultra SupportMartin Avenue Pharmacy48 mg
- Digestive EnzymesGPIin a blend
- Digestive EnzymesWebber Naturals · off the market25 mg
- Digestive EnzymesGNC Women's Ultra Megain a blend
- Digestive EnzymesEarthWell · off the marketin a blend
- Digestive EnzymesTN Trusted Nutrients50 mg
- Digestive EnzymesDr. Mercola · off the marketin a blend
- Digestive EnzymesGNC Beyond Rawin a blend
- Digestive EnzymesMichael's Naturopathic Programsin a blend
- Digestive EnzymesSwanson30 mg
- Digestive EnzymesArazo Nutrition · off the marketin a blend
- Digestive EnzymesSwanson Premium Brand · off the market30 mg
- Digestive Enzymes4Lifein a blend
- Digestive EnzymesMason Natural25 mg
- Digestive EnzymesGNC Mega Menin a blend
- Digestive EnzymesNested Naturalsin a blend
- Digestive EnzymesNutraChampsin a blend
- Digestive EnzymesDivine Bountyin a blend
- Digestive Enzymes1st Phorm100 mg
- Digestive EnzymesGNC Women'sin a blend
- Digestive EnzymesPurely Optimalin a blend
- Digestive EnzymesDouglas Cooper Co.in a blend
- Digestive EnzymesTerra Originin a blend
- Digestive EnzymesBioSchwartzin a blend
- Digestive EnzymesZenwisein a blend