enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 8 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- Daily FormulaUniversal Nutrition / Universal Naturals · off the marketin a blend
- Daily FormulaUniversal · off the marketin a blend
- Daily FormulaUniversal Nutritionin a blend
- Daily Nutrition Shake ChocolatePuritan's Pride Fitnessin a blend
- Daily Nutrition Shake VanillaPuritan's Pride Fitnessin a blend
- Daily Nutritional SupportAltrumin a blend
- Daily Probiotic with Digestive EnzymesWell At Walgreensin a blend
- DailyMulti Iron FreeBluebonnet50 mg
- DailyMulti with IronBluebonnet50 mg
- Dairy & Lactose ToleranceProCaps Laboratories · off the marketin a blend
- Dairy & Lactose ToleranceProCapsin a blend
- Deep Greens Natural FlavorZHOUin a blend
- Delicious Chewable Papaya Enzymes Natural Tropical Flavortnvitamins45 mg
- Detox RxTaylor MD Formulationsin a blend
- Devigest ADS 400 mgArthur Andrew Medicalin a blend
- DGST Support FormulaDouglas Laboratoriesin a blend
- Di-Aide EnzymesProfessional Botanicalsin a blend
- Dieter's Detox Green AppleGNC Earth Genius · off the marketin a blend
- DigenzymeDavinci Laboratories of Vermont · off the market3 mg
- DigenzymeDavinci Laboratories · off the market3 mg
- DigestCustom Health Centersin a blend
- Digest AssureProCaps Laboratoriesin a blend
- Digest ExtraThe Vitamin Shoppein a blend
- Digest HPEAmerican Healthin a blend
- Digest PlusGenestra Brands65 mg
- Digest Smart Critical CareRenew Life · off the marketin a blend
- Digest Smart Extra CareRenew Life · off the marketin a blend
- Digest Smart Plant Based Enzyme Adult 50+ CareRenew Lifein a blend
- Digest Smart Senior CareRenew Life · off the marketin a blend
- Digest Smart Women's CareRenew Lifein a blend
- Digest-A-MintAnabolic Laboratories · off the market100 mg
- Digest-AidHealth Thru Nutrition Naturally75 mg
- Digest-AidHealth Thru Nutrition75 mg
- Digest-EaseAdvoCare50 mg
- Digest-FixPower Blendz Nutritionin a blend
- Digest-FuerteDr. Wong's Essentialsin a blend
- Digest-PlexPatient One 1 MediNutritionals50 mg
- Digest-Rite AdvancedNewtonEverettin a blend
- DigestabsPuritan's Pride130 mg
- DigestBioticsHerbaMein a blend
- DigestEzyNutracraftin a blend
- DigestinPL Progressive Laboratories100 mg
- DigestinProgressive Professional from Progressive Laboratories100 mg
- DigestionGT Genesis Todayin a blend
- Digestion Complex 4-20Nikken Kenzen · off the marketin a blend
- Digestion Complex 4-20Nikken Wellness Kenzenin a blend
- Digestion Enhancement EnzymesHealthForce Nutritionals · off the marketanother unit
- Digestion Enhancement EnzymesHealth Alliance · off the marketin a blend
- Digestion Enhancement EnzymesHealthForce SuperFoodsin a blend
- Digestion MaximizerElevate Recovery Supplements · off the marketin a blend