enzyme
Papain supplements
Half of the 607 papain supplements in the NIH label database that print an amount list 40 mg or less per serving; the middle half list 20 mg to 75 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 1,770607 print an amount; 1,107 list it inside a blend without an amount
- Median per serving
- 40 mgmiddle half 20 mg to 75 mg
How much papain do supplements contain?
The median product lists 40 mg per serving. One in ten lists 5 mg or less, one in ten 170.58 mg or more. The amount printed most often is 50 mg (84 products).
Products by amount of papain per serving
607 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 50 mg | 84 | Systa-Zyme (Bronson Laboratories); Advantage Plus (Douglas Laboratories); Advantage Plus II (Douglas Laboratories) |
| 30 mg | 65 | Life Multi Complete (VitaCeutical Labs); LTP Lyphoactivated Thymic Peptides 600 mg (Ecological Formulas); Life Multi Complete (Vitamer Laboratories) |
| 100 mg | 57 | Zymetec (Douglas Laboratories); OC Pack (Douglas Laboratories); Basics Plus With Copper (Douglas Laboratories) |
| 25 mg | 56 | Acai Daily Cleanse (Vitamin World); Multi-Enzyme Formula (Rexall); Special Two (Vitabase) |
| 20 mg | 34 | V.M.T. Extra Strength (Viva Vitamins); Chewable Papaya (Bio-Nutrient); Complete Digestive Enzymes Formula (Windmill Rx Premium Vitamins) |
| 2 mg | 25 | High Potency One-Per-Day Timed-Release Multi-Vitamins & Minerals (Nature's Harmony); Ultimate Health Complex (Burbank Glendale Chiropractic); Spectra Without Copper And Iron (DaVinci Laboratories Of Vermont) |
| 5 mg | 22 | Parazym-A (Nutri-West); Cardio-Lyph Chelate (Nutri-West); Multibalance For Men (Nutri-West) |
| 45 mg | 22 | Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance) |
| 10 mg | 19 | V.M.T. Regular Strength (Viva Vitamins); Vit-Min 75+ (NOW); Bromelain Plus CLA (Biotics Research Corporation) |
| 200 mg | 19 | Clinical Enzymes (Natural Clinician); Natural Papaya Natural Tropical Fruit Flavor (VitaCeutical Labs); Enzyme Caps (Vitamer Laboratories) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most papain?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Papain 500 mgDr. Clark Research Association Dr. Clark Zentrum1,000 mg
- Papain PowderTerraVita Premium Collection1,000 mg
- Papaya Papain Enzyme 900 mgNusaPure900 mg
- Assault Blue Arctic Raspberry FlavorMusclePharm500 mg
- Assault Raspberry Lemonade FlavorMusclePharm500 mg
- Papain 450 mgTerraVita Premium Collection450 mg
- Priority ZymePriority One Nutritional Supplements360 mg
- Recovery ZymesMNP Michael's Naturopathic Programs360 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2012 list a median of 48 mg; those entered in 2025, 50 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2012 | 43 | 48 mg |
| 2013 | 79 | 32.5 mg |
| 2014 | 20 | 37.5 mg |
| 2015 | 31 | 50 mg |
| 2016 | 41 | 25 mg |
| 2017 | 26 | 30 mg |
| 2018 | 23 | 30 mg |
| 2019 | 29 | 30 mg |
| 2020 | 51 | 45 mg |
| 2021 | 51 | 30 mg |
| 2022 | 58 | 50 mg |
| 2023 | 42 | 30 mg |
| 2024 | 57 | 30 mg |
| 2025 | 45 | 50 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing papain by DSLD product type
Brands listing it most: Nature's Plus (38), Douglas Laboratories (19), Nutri-West (11), Genestra Brands (11), DaVinci Laboratories Of Vermont (10), DC (10), NaturesPlus (9), Priority One Nutritional Supplements (9), Vitamin World (9), DaVinci Laboratories (8).
Every product listing papain
1,770 products, A to Z by name (page 16 of 36), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- HeartburnStop Chewable Tablets RaspberryRenew Life · off the marketin a blend
- Herb Cal TabSunriderin a blend
- Herbal GIGenestra Brands100 mg
- Hi-Potency Multi-Vitamin Delicious Natural Raspberry FlavorWindmillin a blend
- High Potency B-Complex plus B-12Nature's Truth20 mg
- High Potency Digestive Enzyme Pro BlendVitalsin a blend
- High Potency Multi EnzymeNatural Factors2.74 mg
- High Potency Multi Enzyme Vegetarian FormulaNatural Factorsanother unit
- High Potency Multiple VitaminsNew Sun25 mg
- High Potency One-Per-Day Timed-Release Multi-Vitamins & MineralsNature's Harmony2 mg
- Hips, Shoulders, Knees & ToesLaneInnovativein a blend
- HRF-Thalamic Glandular Product with Ascorbic AcidEcological Formulas40 mg
- Hyaluronic Acid PlusOnly Natural · off the market50 mg
- Hyper-DNutri-West62 mg
- Hypo-DNutri-Westin a blend
- Hypo-GestPriority One Nutritional Supplements300 mg
- I.S.P.-PakDC125 mg
- Ibs MdPremium Certifiedin a blend
- Ignite CapsulesVida Divinain a blend
- Immune OneBluebonnetin a blend
- Immuno CapsPriority One Nutritional Supplements18 mg
- Immuno PlusPriority One Nutritional Supplements20 mg
- ImmunogestSynergistic Nutritional Compounds · off the marketin a blend
- InceptionChaotic-Labzin a blend
- Incredible Digestive EnzymesStonehenge Healthin a blend
- Infla-exPhysician's Strengthin a blend
- Infla-KineAidan Productsin a blend
- Infla-MinWellZymes · off the marketanother unit
- Inflam-eezNorth American Herb & Spicein a blend
- Inflama FreeVita Logic20 mg
- Inflama-GIInnate Response Formulasin a blend
- InflamaZymeBioGenesis Nutraceuticals · off the market90 mg
- InflamaZymeNutra BioGenesis120 mg
- Inflamma-LessIrwin Naturalsin a blend
- InflammacidinPremier Research Labs100 mg
- Inflammation ReliefEarth Wise Vitamins & Supplements100 mg
- InflamMotionFuturebioticsin a blend
- InflamMoveNutra Sportin a blend
- InflamMoveVitamin Discount Center · off the marketin a blend
- InflaTechVitaMonkin a blend
- Inner BeautyTerra Origin20 mg
- Inno GreensINNOSUPPSin a blend
- Intensive Strength Digest 13Nature's Bountyanother unit
- Intenzyme ForteBiotics Research Corporation50 mg
- Intestinal FreedomAB American Biologics45 mg
- Intestinal Movement FormulaHealthForce Detox · off the marketin a blend
- Intestinal Movement FormulaHealthForce SuperFoodsin a blend
- Intestinal/GI Support PackDouglas Laboratoriesin a blend
- Intestine Targeted Enzyme Digestive AidGNLD Nutritionals · off the market200 mg
- intraMAX 2.0 Peach Mango FlavorDrucker Labsin a blend