non-nutrient/non-botanical
Silymarin supplements
Half of the 208 silymarin supplements in the NIH label database that print an amount list 116 mg or less per serving; the middle half list 63.75 mg to 203 mg (DSLD version 9.4.0, January 2026).
- Products listing it
- 228208 print an amount; 20 list it inside a blend without an amount
- Median per serving
- 116 mgmiddle half 63.75 mg to 203 mg
How much silymarin do supplements contain?
The median product lists 116 mg per serving. One in ten lists 31.4 mg or less, one in ten 300 mg or more. The amount printed most often is 100 mg (29 products).
Products by amount of silymarin per serving
208 products, log scale; extreme 0.2% at each end left out of the drawing.
| Amount per serving | Products | For example |
|---|---|---|
| 100 mg | 29 | De-Tox Diet & Complexing Aid (Kirkman); Bio Span (Biotivia); Silymarin 100 mg (Life Extension) |
| 200 mg | 17 | Liva Guard Forte Softgels (Perque); Liva Guard Capsules (Perque); Pure Milk Thistle 4:1 Pure Extract Powder (Hard Rhino) |
| 240 mg | 17 | European Milk Thistle (Life Extension); Milk Thistle 300 mg Extract (FoodScience of Vermont); Healthy Liver (WholeHealth) |
| 80 mg | 14 | Milk Thistle 100 mg (Kirkman); Liver Detox (L.A. Naturals); DetoXichol (OTC Pharmaceutical Products) |
| 50 mg | 12 | Pycnogenol Complex (Source Naturals); Wellness Multiple (Source Naturals Wellness); Bioflavonoid Complex (Source Naturals) |
| 60 mg | 11 | WellBetX Glucose Balance Herbal Formula (Natural Factors); Liv-Gall Cleanse (Natural Factors HerbalFactors); Vegan True Vegan Force Multiple (Source Naturals) |
| 140 mg | 10 | Liver Support (AOR Advanced Orthomolecular Research Advanced); Milk Thistle Extract 175 mg (Puritan's Pride); Liver Aid + Milk Thistle (Liverite) |
| 20 mg | 8 | Oxygenics (Metagenics); Anti-Alcohol Antioxidants With HepatoProtection Complex (Life Extension); Anti-Alcohol With HepatoProtection Complex (Life Extension) |
| 30 mg | 7 | Advanced One Multiple (Source Naturals); Menopause Multiple (Source Naturals); Step 2 Detoxitech (Natural Factors) |
| 160 mg | 7 | Liver MD (MD Prescriptives); Liv-a-New (Puritan's Pride); Daily Gentle Cleanse (Irwin Naturals) |
Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).
Which products list the most silymarin?
On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).
- Milk ThistleLife Extension600 mg
- Maximum Strength Milk Thistle Extract 750 mgNOW600 mg
- Milk Thistle ExtractNature's Lab480 mg
- Advanced Milk ThistleLife Extension480 mg
- Detox NowNatrol468 mg
- Full Spectrum Milk Thistle Seed ExtractPlanetary Herbals420 mg
- Full Spectrum Milk Thistle Seed Extract 260 mgPlanetary Herbals420 mg
- Milk Thistle 525 mgNatrol420 mg
Have the amounts changed over the years?
Products whose current label entered DSLD in 2017 list a median of 100 mg; those entered in 2025, 100 mg.
| Year | Products | Median per serving |
|---|---|---|
| 2017 | 20 | 100 mg |
| 2023 | 34 | 140 mg |
| 2024 | 28 | 190 mg |
| 2025 | 30 | 100 mg |
Source: DSLD label entry dates and amounts, current labels.
In which products and brands?
Products listing silymarin by DSLD product type
Brands listing it most: Source Naturals (23), Life Extension (21), NOW (11), Natural Factors (10), Metagenics (6), Metabolic Maintenance (5), Puritan's Pride (5), Rainbow Light (4), Protocol For Life Balance (4), MRM (3).
Every product listing silymarin
228 products, A to Z by name (page 1 of 5), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.
- 2-in-1 Kidney & Liver Super CleanseIrwin Naturals121.5 mg
- AdvaCleanseAkasha Naturals50 mg
- AdvaClearMetagenics50 mg
- Advanced Liver SupportSuper Nutrition240 mg
- Advanced Milk ThistleLife Extension480 mg
- Advanced One MultipleSource Naturals30 mg
- Alpha CRS+doTERRA100 mg
- Alpha CRS+ Cellular Vitality ComplexdoTERRA100 mg
- Anti-Alcohol Antioxidants With HepatoProtection ComplexLife Extension20 mg
- Anti-Alcohol ComplexLife Extension20 mg
- Anti-Alcohol HepatoProtection ComplexLife Extension20 mg
- Anti-Alcohol With HepatoProtection ComplexLife Extension20 mg
- Axis Endo (formerly Estrium) Mango FlavorMetagenics · off the market140 mg
- Axis Endo Mango FlavorMetagenics140 mg
- Beau-TLifeSeasons Therapeutics40 mg
- Berberine 1,000 mg & Silymarin 200 mgPuritan's Pride200 mg
- BerryOxidantsSource Naturals60 mg
- Bio SpanBiotivia100 mg
- Bio Span+ Bio-Enhanced 500 mgBiotivia · off the market200 mg
- Bioflavonoid ComplexSource Naturals50 mg
- Chela-DetoxSource Naturals150 mg
- Clean SlateReset/36050 mg
- CleanseHer Own160 mg
- Cleanse NutriPowderBioCare80 mg
- Cleansing FormulaGNC Preventive Nutrition25 mg
- Clear Change Daily EssentialsMetagenics50 mg
- Complete Liver CleanseNature's Way132.5 mg
- Daily Gentle CleanseIrwin Naturals160 mg
- De-Tox Diet & Complexing AidKirkman100 mg
- Detox & Liver HealthReg'Activ250 mg
- Detox Daily Liver SupportFuturebiotics280 mg
- Detox NowNatrol468 mg
- DetoXicholOTC Pharmaceutical Products80 mg
- DetoxitechNatural Factors30 mg
- Detoxitech Heavy Metal ChelatorNatural Factors150 mg
- Double Strength Milk Thistle 300 mgLuckyHerbs240 mg
- Double Strength Milk Thistle Extract 300 mgNOW240 mg
- Double Strength Policosanol 20 mgNOW80 mg
- Double Strength SilymarinNOW · off the market240 mg
- Double Strength Silymarin Milk Thistle Extract - 300 mgNOW · off the market240 mg
- Elan Vital MultipleSource Naturals187 mg
- European Milk ThistleLife Extension240 mg
- EuroPure Silymarin 200 mgSource Naturals200 mg
- Executive Stress FormulaDouglas Laboratories Ultra Preventive 2000 Series · off the marketin a blend
- Extra Strength L-Glutathione Complex 1000 mgeXplicit Supplements · off the marketin a blend
- Extra Strength Milk Thistle Extract 450 mgNOW360 mg
- Factor (Human Growth Factor Formula) For WomenPrimein a blend
- Fibro-ResponseSource Naturals70 mg
- Full Spectrum Milk Thistle Seed ExtractPlanetary Herbals420 mg
- Full Spectrum Milk Thistle Seed Extract 260 mgPlanetary Herbals420 mg