PlainVitamins

enzyme

Proteolytic Enzymes (Proteases) supplements

Half of the 327 proteolytic enzymes (proteases) supplements in the NIH label database that print an amount list 30 mg or less per serving; the middle half list 10 mg to 100 mg (DSLD version 9.4.0, January 2026).

Products listing it
3,003327 print an amount; 2,433 list it inside a blend without an amount
Median per serving
30 mgmiddle half 10 mg to 100 mg

How much proteolytic enzymes (proteases) do supplements contain?

The median product lists 30 mg per serving. One in ten lists 3.73 mg or less, one in ten 200 mg or more. The amount printed most often is 50 mg (29 products).

Products by amount of proteolytic enzymes (proteases) per serving

327 products, log scale; extreme 0.2% at each end left out of the drawing.

Proteolytic Enzymes (Proteases): products by amount per serving0.3 mg3 mg30 mg300 mg
Proteolytic Enzymes (Proteases): products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg
Proteolytic Enzymes (Proteases): products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
Proteolytic Enzymes (Proteases): products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
Proteolytic Enzymes (Proteases): products by amount per serving0.3 mg1 mg3 mg10 mg30 mg100 mg300 mg
The amounts printed most often
Amount per servingProductsFor example
50 mg29 Multi-Enzyme Formula (Rexall); AllerGzyme (Designs for Health); Total Liver D-Tox (Nutri-West)
20 mg24 Papaya Enzyme Chewable (Nature's Harmony); Green Vibrance Chocolate Coconut (Vibrant Health); HMF Digest-Zyme (Genestra Brands)
125 mg24 Monster Blend "Weidman's" Chocolate Peanut Butter Banana (CytoSport); Monster Milk Vanilla Creme (CytoSport); Monster Milk Strawberries 'N Creme (CytoSport)
5 mg22 Complete Gluco-D (Nutri-West); MultiNutrient (Bluebonnet Super Earth); MultiNutrient Iron Free (Bluebonnet Super Earth)
10 mg19 B-Complex And B-12 (Vitamin World); B-Complex & B-12 (Radiance); B-Complex With B-12 (Nature's Bounty)
6 mg15 Zygest Papaya Enzyme (Vitamin World); Original Papaya Enzyme (Puritan's Pride); Original Papaya Enzyme (Radiance)
3 mg10 Zygest Super Papaya Plus (Vitamin World); Papaya Enzyme (Botanic Choice); Chewable Super Papaya Enzyme Plus (Puritan's Pride Premium)
25 mg9 All Day Energy Green Zing (IVL Institute for Vibrant Living); Men's Sport One Daily (BodyTech); Nutritional Drink Mix Chocolate (Altrum)
15 mg8 Zygest Multi-Enzyme (Vitamin World); Digestive Enzymes (TN Trusted Nutrients); Women's One Multiple (AN Amazing Nutrition Amazing Formulas)
30 mg8 Zygest Maximum Strength Multi-Enzyme (Vitamin World); Liverclean (Dr. Venessa's Formulas); Zygest Multi-Enzyme Broad Spectrum Formula (Vitamin World)

Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).

Which products list the most proteolytic enzymes (proteases)?

On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).

Have the amounts changed over the years?

Products whose current label entered DSLD in 2013 list a median of 45 mg; those entered in 2025, 20 mg.

Median proteolytic enzymes (proteases) per serving by the year the label entered DSLD (years with 20+ products)
YearProductsMedian per serving
20132445 mg
201522125 mg
20162330 mg
20203240.5 mg
20213248.5 mg
20222145 mg
20232420 mg
20244433.13 mg
20252420 mg

Source: DSLD label entry dates and amounts, current labels.

In which products and brands?

Products listing proteolytic enzymes (proteases) by DSLD product type

Proteolytic Enzymes (Proteases) by product typeOther Combinations256Non-Nutrient/Non-Botanical64Botanical with Nutrients4Amino acid/Protein2Multi-Vitamin and Mineral (MVM)1
Proteolytic Enzymes (Proteases) by product typeOther Combinations256Non-Nutrient/Non-Botanical64Botanical with Nutrients4Amino acid/Protein2Multi-Vitamin and Mineral (MVM)1
Proteolytic Enzymes (Proteases) by product typeOther Combinations256Non-Nutrient/Non-Botanical64Botanical with Nutrients4Amino acid/Protein2Multi-Vitamin and Mineral (MVM)1
Proteolytic Enzymes (Proteases) by product typeOther Combinations256Non-Nutrient/Non-Botanical64Botanical with Nutrients4Amino acid/Protein2Multi-Vitamin and Mineral (MVM)1
Proteolytic Enzymes (Proteases) by product typeOther Combinations256Non-Nutrient/Non-Botanical64Botanical with Nutrients4Amino acid/Protein2Multi-Vitamin and Mineral (MVM)1

Brands listing it most: Nature's Plus (13), CytoSport (13), ProEnzol (12), Vitamin World (9), CytoSport Monster Series (9), NaturesPlus (8), ProSol (8), WellZymes (7), Bluebonnet (6), Good 'N Natural (5).

Every product listing proteolytic enzymes (proteases)

3,003 products, A to Z by name (page 52 of 61), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.

Where next?