Estro Support ES

by 21st Century · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 7 40985 27007 3
  • DSLD label 207388
  • Serving 1 tablet; amounts per 2 tablets
  • 30 servings

Estro Support ES by 21st Century lists 20 ingredients, 15 with an amount per serving of 2 tablets, such as 20 mg of vitamin E, 5 mg of thiamine, 5 mg of riboflavin and 20 mg of niacin; 5 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on October 23, 2019.

What is in Estro Support ES?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Estro Support ES: Supplement Facts rows against the market (DSLD label 207388, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Eas D-Alpha-Tocopheryl SuccinateVitamin E (Form: as D-Alpha Tocopheryl Succinate)20 mg134%
Thiamineas Thiamine MononitrateThiamin (Form: as Thiamin Mononitrate)5 mg417%Thiamin in Estro Support ES against 9,830 products5 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg5 mg

46% of 9,830 products listing thiamin give more (median 5 mg). Per day at the most servings: 10 mg.

Riboflavinas Vitamin B25 mg385%Riboflavin in Estro Support ES against 9,824 products5 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg5 mg

Higher than 51% of 9,824 products listing riboflavin (median 4 mg). Per day at the most servings: 10 mg.

Niacinas NiacinamideNiacin (Form: as Niacinamide)20 mg125%Niacin in Estro Support ES against 12,413 products20 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg20 mg

46% of 12,413 products listing niacin give more (median 20 mg). Per day at the most servings: 40 mg. 1.1 times the adult UL a day.

Vitamin B6as Pyridoxine HydrochlorideVitamin B-6 (Form: as Pyridoxine HCl)25 mg1,471%Vitamin B6 in Estro Support ES against 15,277 products25 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg25 mg

Higher than 76% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 50 mg.

Folate667 mg DFE167%
Folic Acid400 mcg
Vitamin B12as CyanocobalaminVitamin B-12 (Form: as Cyanocobalamin)25 mcg1,042%Vitamin B12 in Estro Support ES against 14,425 products25 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg25 mcg

54% of 14,425 products listing vitamin B12 give more (median 36 mcg). Per day at the most servings: 50 mcg.

Calciumas Calcium CarbonateCalcium (Form: as Calcium Carbonate)200 mg15%Calcium in Estro Support ES against 17,831 products200 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg200 mg

Higher than 64% of 17,831 products listing calcium (median 115 mg). Per day at the most servings: 400 mg.

Seleniumas L-SelenomethionineSelenium (Form: as L-Selenomethionine)70 mcg127%Selenium in Estro Support ES against 7,658 products70 mcg per serving; the middle half of products list 27 mcg to 100 mcg, the median 55 mcg.DV 55 mcgUL 400 mcg70 mcg

Higher than 52% of 7,658 products listing selenium (median 55 mcg). Per day at the most servings: 140 mcg.

Chromiumas Chromium Dinicotinate GlycinateChromium (Form: as Chromium Dinicotinate Glycinate)120 mcg343%Chromium in Estro Support ES against 7,825 products120 mcg per serving; the middle half of products list 45 mcg to 200 mcg, the median 100 mcg.DV 35 mcg120 mcg

Higher than 54% of 7,825 products listing chromium (median 100 mcg). Per day at the most servings: 240 mcg.

Boronas Boron Amino Acid ChelateBoron (Form: as Boron Amino Acid Chelate)1.5 mgBoron in Estro Support ES against 3,339 products1.5 mg per serving; the middle half of products list 0.3 mg to 2 mg, the median 1 mg.UL 20 mg1.5 mg

Higher than 58% of 3,339 products listing boron (median 1 mg). Per day at the most servings: 3 mg.

Estro Support Herbal Blend200 mg
Green Tea extractin the blend, no amount given
Date seed extractin the blend, no amount given
Cinnamonin the blend, no amount given
Galangal root extractin the blend, no amount given
Magnolia bark extractin the blend, no amount given
purified Isoflavonesas Soybean extractpurified Isoflavones (Form: from standardized Soybean extract)80 mgIsoflavones in Estro Support ES against 290 products80 mg per serving; the middle half of products list 25 mg to 80 mg, the median 50 mg.80 mg

Higher than 72% of 290 products listing isoflavones (median 50 mg). Per day at the most servings: 160 mg.

Black Cohosh extract40 mgBlack Cohosh in Estro Support ES against 431 products40 mg per serving; the middle half of products list 40 mg to 160 mg, the median 80 mg.40 mg

68% of 431 products listing black cohosh give more (median 80 mg). Per day at the most servings: 80 mg.

CranberryCranberry PlantPart: juice Note: from 12:1 extract300 mgCranberry in Estro Support ES against 1,064 products300 mg per serving; the middle half of products list 97.5 mg to 500 mg, the median 250 mg.300 mg

Higher than 53% of 1,064 products listing cranberry (median 250 mg). Per day at the most servings: 600 mg.

Source: NIH ODS Dietary Supplement Label Database, label 207388 (entered October 23, 2019), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 2 servings a day, the most its directions give, the label lists 40 mg of niacin, 1.1 times the adult Tolerable Upper Intake Level.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take one (1) tablet with any meal, twice daily or as directed by a healthcare provider. Do not exceed recommended dosage.
Warnings
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Contains soy.
Allergens and what it does not contain
No added Sugar, Yeast, Preservatives or Artificial Flavors.
Gluten free
Storage
Store at room temperature.

Source: label statements in DSLD label 207388.

What else is on the label?

Other ingredients: Maltodextrin, Croscarmellose Sodium, Cellulose, Silicon Dioxide, Stearic Acid, Contains Less Than 2% of.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed quality Laboratory tested.

How many labels does Estro Support ES have?

3 labels are on file under this name since July 25, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 207388 (current) Entered October 23, 2019 · on the market · 60 tablets · UPC 7 40985 27007 3
  2. Label 43811 Entered March 25, 2015 · off the market March 14, 2019 · 60 tablets · UPC 7 40985 27007 3
  3. Label 11232 Entered July 25, 2012 · off the market April 1, 2014 · 60 caplets · UPC 7 40985 27007 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?