PlainVitamins

Advanced Formula Hair, Skin & Nails

by 21st Century · other (e.g. tea bag) · 50 caplets

  • Off the market since July 2023 (NIH)
  • DSLD label 46700
  • Serving 1 to 2 caplets; amounts per 1 caplet

Advanced Formula Hair, Skin & Nails by 21st Century lists 52 ingredients, 29 with an amount per serving of 1 caplet, such as 2,500 IU of vitamin A, 50 mg of vitamin C, 50 IU (1.25 mcg) of vitamin D and 25 IU of vitamin E; 23 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on June 25, 2015.

What is in Advanced Formula Hair, Skin & Nails?

Each row as the label prints it, per serving of 1 caplet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced Formula Hair, Skin & Nails: Supplement Facts rows against the market (DSLD label 46700, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Aas Vitamin A Palmitate2,500 IU50%Vitamin A in Advanced Formula Hair, Skin & Nails against 5,772 products2,500 IU per serving; the middle half of products list 2,000 IU to 5,000 IU, the median 4,000 IU.2,500 IU

59% of 5,772 products listing vitamin A give more (median 4,000 IU).

Vitamin Cas Ascorbic Acid50 mg83%Vitamin C in Advanced Formula Hair, Skin & Nails against 18,583 products50 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg50 mg

77% of 18,583 products listing vitamin C give more (median 100 mg).

Vitamin Das Cholecalciferol50 IU (1.25 mcg)13%Vitamin D in Advanced Formula Hair, Skin & Nails against 14,175 products1.25 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg1.25 mcg

97% of 14,175 products listing vitamin D give more (median 15 mcg).

Vitamin Eas DL-Alpha-Tocopheryl Acetate25 IU83%Vitamin E in Advanced Formula Hair, Skin & Nails against 6,459 products25 IU per serving; the middle half of products list 15 IU to 100 IU, the median 30 IU.25 IU

68% of 6,459 products listing vitamin E give more (median 30 IU).

Thiamineas Thiamine Mononitrate, Vitamin B15 mg333%Thiamin in Advanced Formula Hair, Skin & Nails against 9,830 products5 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg5 mg

46% of 9,830 products listing thiamin give more (median 5 mg).

Riboflavinas Vitamin B25 mg294%Riboflavin in Advanced Formula Hair, Skin & Nails against 9,824 products5 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg5 mg

Higher than 51% of 9,824 products listing riboflavin (median 4 mg).

Niacin7.5 mg38%Niacin in Advanced Formula Hair, Skin & Nails against 12,413 products7.5 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg7.5 mg

86% of 12,413 products listing niacin give more (median 20 mg).

Vitamin B6as Pyridoxine Hydrochloride6.5 mg325%Vitamin B6 in Advanced Formula Hair, Skin & Nails against 15,277 products6.5 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg6.5 mg

Higher than 51% of 15,277 products listing vitamin B6 (median 6 mg).

Folic Acid25 mcg6%Folate in Advanced Formula Hair, Skin & Nails against 7,022 products25 mcg per serving; the middle half of products list 200 mcg to 400 mcg, the median 400 mcg.25 mcg

97% of 7,022 products listing folate give more (median 400 mcg).

Vitamin B12as Cyanocobalamin25 mcg416%Vitamin B12 in Advanced Formula Hair, Skin & Nails against 14,425 products25 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg25 mcg

54% of 14,425 products listing vitamin B12 give more (median 36 mcg).

Biotin25 mcg8%Biotin in Advanced Formula Hair, Skin & Nails against 9,447 products25 mcg per serving; the middle half of products list 50 mcg to 300 mcg, the median 200 mcg.DV 30 mcg25 mcg

92% of 9,447 products listing biotin give more (median 200 mcg).

Pantothenic Acidas D-Calcium Pantothenate15 mg150%Pantothenic Acid (Vitamin B5) in Advanced Formula Hair, Skin & Nails against 10,060 products15 mg per serving; the middle half of products list 6 mg to 50 mg, the median 12 mg.DV 5 mg15 mg

Higher than 51% of 10,060 products listing pantothenic acid (vitamin B5) (median 12 mg).

Calciumas Calcium Phosphate70 mg7%Calcium in Advanced Formula Hair, Skin & Nails against 17,831 products70 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg70 mg

65% of 17,831 products listing calcium give more (median 115 mg).

Ironas Ferrous Fumarate3.3 mg18%Iron in Advanced Formula Hair, Skin & Nails against 6,910 products3.3 mg per serving; the middle half of products list 1.2 mg to 18 mg, the median 5 mg.DV 18 mgUL 45 mg3.3 mg

60% of 6,910 products listing iron give more (median 5 mg).

Phosphorusas Calcium Phosphate54 mg5%Phosphorus in Advanced Formula Hair, Skin & Nails against 3,786 products54 mg per serving; the middle half of products list 45 mg to 200 mg, the median 90 mg.DV 1,250 mgUL 4,000 mg54 mg

68% of 3,786 products listing phosphorus give more (median 90 mg).

Iodineas Potassium Iodide150 mg100%

This amount is far outside what other labels list for iodine, or disagrees with the label's own %DV: possibly a unit or transcription slip in the database. Check the label image on DSLD.

Magnesiumas Magnesium Oxide20 mg5%Magnesium in Advanced Formula Hair, Skin & Nails against 14,003 products20 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg20 mg

83% of 14,003 products listing magnesium give more (median 86 mg).

Zincas Zinc Gluconate0.6 mg4%Zinc in Advanced Formula Hair, Skin & Nails against 13,186 products0.6 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg0.6 mg

98% of 13,186 products listing zinc give more (median 11 mg).

Manganeseas Manganese Sulfate0.6 mg30%Manganese in Advanced Formula Hair, Skin & Nails against 7,016 products0.6 mg per serving; the middle half of products list 1 mg to 3.92 mg, the median 2 mg.DV 2.3 mgUL 11 mg0.6 mg

85% of 7,016 products listing manganese give more (median 2 mg).

Potassiumas Potassium Sulfate897 mcg1%

This amount is far outside what other labels list for potassium, or disagrees with the label's own %DV: possibly a unit or transcription slip in the database. Check the label image on DSLD.

Cholineas Choline Bitartrate25 mg5%*Choline in Advanced Formula Hair, Skin & Nails against 4,738 products25 mg per serving; the middle half of products list 18 mg to 100 mg, the median 40 mg.DV 550 mgUL 3,500 mg25 mg

59% of 4,738 products listing choline give more (median 40 mg).

Betaine10 mgBetaine in Advanced Formula Hair, Skin & Nails against 731 products10 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.10 mg

94% of 731 products listing betaine give more (median 250 mg).

Inositol10 mgInositol in Advanced Formula Hair, Skin & Nails against 4,042 products10 mg per serving; the middle half of products list 10 mg to 80 mg, the median 30 mg.10 mg

72% of 4,042 products listing inositol give more (median 30 mg).

Paba10 mgPABA in Advanced Formula Hair, Skin & Nails against 1,610 products10 mg per serving; the middle half of products list 10 mg to 50 mg, the median 25 mg.10 mg

72% of 1,610 products listing PABA give more (median 25 mg).

Dna10 mgDNA in Advanced Formula Hair, Skin & Nails against 78 products10 mg per serving; the middle half of products list 1 mg to 7.88 mg, the median 2.3 mg.10 mg

Higher than 77% of 78 products listing DNA (median 2.3 mg).

Rna10 mgRNA in Advanced Formula Hair, Skin & Nails against 159 products10 mg per serving; the middle half of products list 5 mg to 47.5 mg, the median 20 mg.10 mg

55% of 159 products listing RNA give more (median 20 mg).

Tyrosine7.2 mgTyrosine in Advanced Formula Hair, Skin & Nails against 1,680 products7.2 mg per serving; the middle half of products list 150 mg to 989 mg, the median 500 mg.7.2 mg

99% of 1,680 products listing tyrosine give more (median 500 mg).

Cysteine3.5 mgCysteine in Advanced Formula Hair, Skin & Nails against 516 products3.5 mg per serving; the middle half of products list 30 mg to 200 mg, the median 85 mg.3.5 mg

94% of 516 products listing cysteine give more (median 85 mg).

Soy ProteinSoy Protein Note: Amino Acid Blend50 mgSoy Protein in Advanced Formula Hair, Skin & Nails against 46 products50 mg per serving; the middle half of products list 62.5 mg to 487.5 mg, the median 142.5 mg.50 mg

74% of 46 products listing soy protein give more (median 142.5 mg).

Amino Acid Blendno amount given
Glutamic Acidno amount given
Lysineno amount given
Leucineno amount given
Aspartic Acidno amount given
Isoleucineno amount given
Valineno amount given
Alanineno amount given
Arginineno amount given
Histidineno amount given
Serineno amount given
Show the other 14 rows of the label
Advanced Formula Hair, Skin & Nails: rows 41 to 54
IngredientAmount% DVAmong products listing it
Threonineno amount given
Glycineno amount given
Ornithineno amount given
Proprietary Herbal Support Blend310 mg
Brewers Yeastin the blend, no amount given
Soy Proteinin the blend, no amount given
Horsetailin the blend, no amount given
Parsleyin the blend, no amount given
Rose Hipsin the blend, no amount given
Watercressin the blend, no amount given
Kelpin the blend, no amount given
Citrus Bioflavonoidsin the blend, no amount given
Lecithinin the blend, no amount given
Rutinin the blend, no amount given

* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.

Source: NIH ODS Dietary Supplement Label Database, label 46700 (entered June 25, 2015), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 97% of the 14,175 products that print an amount of vitamin D list more than its 1.25 mcg (50 IU) of vitamin D (median 15 mcg (600 IU)).
  • 97% of the 7,022 products that print an amount of folate list more than its 25 mcg of folic acid (filed by NIH under folate) (median 400 mcg).
  • 92% of the 9,447 products that print an amount of biotin list more than its 25 mcg of biotin (median 200 mcg).
  • 98% of the 13,186 products that print an amount of zinc list more than its 0.6 mg of zinc (median 11 mg).
  • 94% of the 731 products that print an amount of betaine list more than its 10 mg of betaine (median 250 mg).
  • 99% of the 1,680 products that print an amount of tyrosine list more than its 7.2 mg of tyrosine (median 500 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Advanced Formula Hair, Skin & Nails's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one (1) or two (2) caplets daily with any meal for maximum daily results, or as directed by healthcare provider.
Warnings
Instructions: Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Allergens and what it does not contain
No added Sugar, Salt, Yeast, Preservatives, or Artificial Flavors.
Storage
Store at room temperature.

Source: label statements in DSLD label 46700.

What else is on the label?

Other ingredients: Calcium Carbonate, Stearic Acid, Cellulose, Maltodextrin, Croscarmellose Sodium, Silicon Dioxide, Titanium Dioxide, Magnesium Stearate, Artificial colors.

How many labels does Advanced Formula Hair, Skin & Nails have?

One label is on file, entered on June 25, 2015.

  1. Label 46700 (current) Entered June 25, 2015 · off the market July 18, 2023 · 50 caplets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century (manufacturer). All 21st Century products.

Where next?