non-nutrient/non-botanical

Berberine supplements

Half of the 419 berberine supplements in the NIH label database that print an amount list 400 mg or less per serving; the middle half list 131.5 mg to 500 mg (DSLD version 9.4.0, January 2026). The 117 products whose only supplement ingredient is berberine list a median of 500 mg.

Products listing it
522419 print an amount; 103 list it inside a blend without an amount
Median per serving
400 mgmiddle half 131.5 mg to 500 mg

How much berberine do supplements contain?

The median product lists 400 mg per serving. One in ten lists 50 mg or less, one in ten 1,000 mg or more. The amount printed most often is 500 mg (98 products).

Products by amount of berberine per serving

419 products, log scale; extreme 0.2% at each end left out of the drawing.

Berberine: products by amount per serving3 mg10 mg30 mg100 mg
Berberine: products by amount per serving3 mg10 mg30 mg100 mg300 mg1,000 mg
Berberine: products by amount per serving3 mg10 mg30 mg100 mg300 mg1,000 mg
Berberine: products by amount per serving3 mg10 mg30 mg100 mg300 mg1,000 mg
Berberine: products by amount per serving3 mg10 mg30 mg100 mg300 mg1,000 mg
The amounts printed most often
Amount per servingProductsFor example
500 mg98 Youthful Metabolism (Juvenon); Berberine+ GlucoDefense (Dr. Whitaker); WellBetX Berberine 500 mg (Natural Factors)
1,000 mg36 Glucorol SX (HoltraCeuticals); Morphoprime (Morphogen Nutrition); Berberine Plus 1000 mg (Nova Nutritions)
100 mg33 GI Microb-X (Designs for Health); Sinatrol (Ortho Molecular Products); MicroDefense (Pure Encapsulations)
1,200 mg29 Advanced Berberine 1200 (Bio Nutrition); Stabilize (Arms Race Nutrition); Premium Berberine+ Plus1200 mg Extra Strength (Nutrivein)
200 mg27 Cleanse Supplements (Clean); Cystistatin (Ortho Molecular Products); GlucoCell (VitaMonk)
400 mg24 Glucose Management With Berberine HCl (Protocol For Life Balance); Berberine (Good State); Ultra MFP Forte (Douglas Laboratories)
250 mg20 Ultimate Heart Health (Natural Factors); Glyco-X 250 (Good State); Hepatodyne (Allergy Research Group)
50 mg16 KandidaPlex (Vitamin Research Products); Fungal Fighter 400 mg (Dr. Clark Store); Ember (Ambrosia Collective)
150 mg16 Candicid Forte (Ortho Molecular Products); Pyloricil (Ortho Molecular Products); EndoLOX (Pure Encapsulations)
300 mg11 Rpg (Redcon1); GlycoLog (Blackstone Labs); SpiroLaze (Wholly Liquid)

Source: Supplement Facts rows of every product's current label, NIH ODS Dietary Supplement Label Database version 9.4.0; amounts in one measure (weight).

Which products list the most berberine?

On-market products, per serving, with a plausible amount: the rule leaves out likely entry slips, such as an amount far beyond every other label with no %DV or strength on the label to back it (each product page still shows its own amount, marked).

Have the amounts changed over the years?

Products whose current label entered DSLD in 2020 list a median of 450 mg; those entered in 2025, 457 mg.

Median berberine per serving by the year the label entered DSLD (years with 20+ products)
YearProductsMedian per serving
202038450 mg
202158400 mg
202244450 mg
202358325 mg
202477500 mg
202577457 mg

Source: DSLD label entry dates and amounts, current labels.

In which products and brands?

Products listing berberine by DSLD product type

Berberine by product typeOther Combinations279Non-Nutrient/Non-Botanical117Botanical21Botanical with Nutrients2
Berberine by product typeOther Combinations279Non-Nutrient/Non-Botanical117Botanical21Botanical with Nutrients2
Berberine by product typeOther Combinations279Non-Nutrient/Non-Botanical117Botanical21Botanical with Nutrients2
Berberine by product typeOther Combinations279Non-Nutrient/Non-Botanical117Botanical21Botanical with Nutrients2
Berberine by product typeOther Combinations279Non-Nutrient/Non-Botanical117Botanical21Botanical with Nutrients2

Brands listing it most: Solaray (11), Thorne (10), Nature's Answer (9), Pure Encapsulations (8), Whitaker Nutrition (8), Justified Laboratories (7), Ortho Molecular Products (7), HoltraCeuticals (7), Thorne Research (7), XYMOGEN (6).

Every product listing berberine

522 products, A to Z by name (page 1 of 11), each with the amount its label prints; an amount far outside what other labels print is marked as a possible slip.

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