Berberine

by Thorne · capsule · 60 capsules

  • On the market (NIH)
  • UPC 6 93749 04800 8
  • DSLD label 328820
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 30 servings

Berberine by Thorne lists 2 ingredients, 2 with an amount per serving of 2 capsules, such as 450 mg of berberine hydrochloride and 550 mg of berbevis. Its current label entered the NIH Dietary Supplement Label Database on February 23, 2025.

What is in Berberine?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Berberine: Supplement Facts rows against the market (DSLD label 328820, January 2026 release)
IngredientAmount% DVAmong products listing it
Berberine Hydrochlorideas Indian Barberry Root Extract450 mgBerberine in Berberine against 419 products1,000 mg per serving; the middle half of products list 131.5 mg to 500 mg, the median 400 mg.1,000 mg

Higher than 83% of 419 products listing berberine (median 400 mg). Per day at the most servings: 2,000 mg.

Berbevisas Berberine PhytosomeThis product uses Indena S.p.A's berberine phytosome (Berbevis). Berbevis is a registered trademark of Indena S.p.A.550 mg

Source: NIH ODS Dietary Supplement Label Database, label 328820 (entered February 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: Take 1-2 capsules two times daily with food or as recommended by your health-care practitioner.
Warnings
Tamper evident: Use only if bottle is sealed.
Warning: If pregnant, nursing, or trying to conceive, do not use this product.
Allergens and what it does not contain
Gluten free
Storage
Store tightly sealed in a cool, dry place.

Source: label statements in DSLD label 328820.

What else is on the label?

Other ingredients: Hypromellose, Calcium Laurate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Manufactured in the USA using US & imported ingredients Contents Certified NSF. Listed with: NSF certified (contents or GMP) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Berberine have?

3 labels are on file under this name since September 25, 2023: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 328820 (current) Entered February 23, 2025 · on the market · 60 capsules · UPC 6 93749 04800 8
  2. Label 306244 Entered January 24, 2024 · off the market October 22, 2024 · 60 capsules · UPC 6 93749 04800 8
  3. Label 298058 Entered September 25, 2023 · on the market · 60 capsules · UPC 6 93749 76002 3

DSLD also links this label to: Berberine-500 (image difference, same product), Berberine-500 (image difference, same product), Berberine-500 (image difference, same product), Berberine-500 (image difference, same product), Berberine-500 (image difference, same product), Berberine 1000 mg (image difference, same product), Berberine 1000 mg (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Thorne Research, Inc. (manufacturer). All Thorne products.

Where next?