MicroDefense

by Pure Encapsulations · capsule · 180 capsules

  • On the market (NIH)
  • UPC 7 66298 01665 8
  • DSLD label 184659
  • Serving 1 capsule
  • 180 servings

MicroDefense by Pure Encapsulations lists 5 ingredients, 5 with an amount per serving of 1 capsule, such as 100 mg of berberine sulfate, 100 mg of olive (olea europaea) extract, 200 mg of sweet wormwood (artemisia annua) extract and 75 mg of clove (syzygium aromaticum) powder. Its current label entered the NIH Dietary Supplement Label Database on February 25, 2019.

What is in MicroDefense?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MicroDefense: Supplement Facts rows against the market (DSLD label 184659, January 2026 release)
IngredientAmount% DVAmong products listing it
Berberine Sulfate100 mgBerberine in MicroDefense against 419 products100 mg per serving; the middle half of products list 131.5 mg to 500 mg, the median 400 mg.100 mg

76% of 419 products listing berberine give more (median 400 mg).

Olive (Olea europaea) extractas OleuropeinOlive (Olea europaea) extract (Form: standardized to contain 15% Oleuropein) PlantPart: leaf Genus: Olea Species: europaea100 mgOlive in MicroDefense against 822 products100 mg per serving; the middle half of products list 30 mg to 300 mg, the median 100 mg.100 mg

47% of 822 products listing olive give more (median 100 mg).

Sweet Wormwood (Artemisia annua) extract200 mgSweet Annie in MicroDefense against 48 products200 mg per serving; the middle half of products list 150 mg to 500 mg, the median 300 mg.200 mg

54% of 48 products listing sweet annie give more (median 300 mg).

Clove (Syzygium aromaticum) powder75 mgClove in MicroDefense against 110 products75 mg per serving; the middle half of products list 20 mg to 224 mg, the median 60 mg.75 mg

Higher than 55% of 110 products listing clove (median 60 mg).

Grapefruit (Citrus x paradisi) extract85 mgGrapefruit in MicroDefense against 220 products85 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.85 mg

55% of 220 products listing grapefruit give more (median 100 mg).

Source: NIH ODS Dietary Supplement Label Database, label 184659 (entered February 25, 2019), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with MicroDefense's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendations: As a dietary supplement, take 1 capsule daily, just before a meal, with 6-8 oz water, for 2-3 months, or as directed by a health professional.
Warnings
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Allergens and what it does not contain
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Gluten-free, Non-GMO & Hypoallergenic
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 184659.

What else is on the label?

Other ingredients: Vegetarian Capsule, hypoallergenic Plant Fiber.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GF.

How many labels does MicroDefense have?

3 labels are on file under this name since January 7, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 219521 Entered May 22, 2020 · off the market November 30, 2018 · 180 capsules · UPC 7 66298 01665 8
  2. Label 184659 (current) Entered February 25, 2019 · on the market · 180 capsules · UPC 7 66298 01665 8
  3. Label 185088 Entered January 7, 2019 · on the market · 90 capsules · UPC 7 66298 01666 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Pure Encapsulations (manufacturer), Sudbury, MA. All Pure Encapsulations products.

Where next?