Berberine
by Enzymedica · capsule · 60 targeted-delivery capsules
- On the market (NIH)
- UPC 6 70480 10083 7
- DSLD label 328873
- Serving 1 capsule
- 60 servings
Berberine by Enzymedica lists 2 ingredients, 2 with an amount per serving of 1 capsule, such as 510 mg of berberine hydrochloride and 50 mg of leucine. Its current label entered the NIH Dietary Supplement Label Database on April 24, 2025.
What is in Berberine?
Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Berberine Hydrochlorideas Berberis aristata, Berberis aristata95% | 510 mg | Higher than 79% of 419 products listing berberine (median 400 mg). Per day at the most servings: 1,530 mg. | |
| Leucine | 50 mg | 95% of 2,056 products listing leucine give more (median 2.5 g). Per day at the most servings: 0.15 g. |
Source: NIH ODS Dietary Supplement Label Database, label 328873 (entered April 24, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- 95% of the 2,056 products that print an amount of leucine list more than its 0.05 g of leucine (median 2.5 g).
The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with Berberine's, rare ingredients counting for more.
- BerbercapThorne Research · off the market 1 shared, 60% alike
- Berberine-500Thorne Research · off the market 1 shared, 60% alike
- Berberine 1,000Only Natural · off the market 1 shared, 60% alike
- Advanced Berberine 1200Bio Nutrition 1 shared, 60% alike
- Berberine 500 mgDr. Whitaker · off the market 1 shared, 60% alike
- Berberine 500 mgPatient One MediNutritionals · off the market 1 shared, 60% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Recommended use: 1 capsule with meals, three times a day.
- Warnings
- Caution: This product is not intended for individuals with impaired glucose metabolism such as prediabetes or diabetes.
- Consult with physician prior to use if you are pregnant or nursing, taking medications or have a medical condition.
- Do not use if safety seal is broken or missing.
- Please keep out of reach of children
- Allergens and what it does not contain
- Non GMO Certified by NSF
- Contains no: gluten, milk, casein, soy, egg, artificial colors or flavors
- Storage
- Keep closed in dry place; avoid excessive heat.
Source: label statements in DSLD label 328873.
What else is on the label?
Other ingredients: Cellulose, Gellan Gum, Water, Rice Concentrate, Calcium Laurate.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): AHA Autism Hope Alliance Green Mountain Energy 30 Day Money Back Guarantee; United Plant Savers Medicinal Plant Conservation. Listed with: NSF certified (contents or GMP) (a seal is the label's claim; the certifier's own list confirms it).
How many labels does Berberine have?
2 labels are on file under this name since September 25, 2023: other sizes, label designs and reformulations. The current one leads this page.
- Label 328873 (current) Entered April 24, 2025 · on the market · 60 targeted-delivery capsules · UPC 6 70480 10083 7
- Label 296456 Entered September 25, 2023 · on the market · 120 targeted delivery capsules · UPC 6 70480 10085 1
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Enzymedica, Inc. (manufacturer), Venice, FL. All Enzymedica products.