PlainVitamins

Folate Methylation

by Priority One Nutritional Supplements · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 8 15354 02055 6
  • DSLD label 277360
  • Serving 2 vegetarian capsules
  • 30 servings

Folate Methylation by Priority One Nutritional Supplements lists 13 ingredients, 13 with an amount per serving of 2 vegetarian capsules, such as 49 mg of thiamine hydrochloride, 50 mg of riboflavin, 50 mg NE of niacin and 30 mg of vitamin B6. Its current label entered the NIH Dietary Supplement Label Database on November 22, 2022.

What is in Folate Methylation?

Each row as the label prints it, per serving of 2 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Folate Methylation: Supplement Facts rows against the market (DSLD label 277360, January 2026 release)
IngredientAmount% DVAmong products listing it
Thiamine Hydrochlorideas Vitamin B149 mg4,104%Thiamin in Folate Methylation against 9,830 products49 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg49 mg

Higher than 82% of 9,830 products listing thiamin (median 5 mg).

Riboflavinas Riboflavin-5-Phosphate Sodium50 mg3,846%Riboflavin in Folate Methylation against 9,824 products50 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg50 mg

Higher than 86% of 9,824 products listing riboflavin (median 4 mg).

Niacinas Niacinamide, Vitamin B350 mg NE313%Niacin in Folate Methylation against 12,413 products50 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg50 mg

Higher than 75% of 12,413 products listing niacin (median 20 mg). 1.4 times the adult UL a day.

Vitamin B6as Pyridoxal 5-Phosphate30 mg1,765%Vitamin B6 in Folate Methylation against 15,277 products30 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg30 mg

Higher than 82% of 15,277 products listing vitamin B6 (median 6 mg).

Folateas (6S)-5-Methyltetrahydrofolic AcidFolate (Form: as (6S)-5-Methyltetrahydrofolic Acid (Alt. Name: Quatrefolic) Note: equivalent to 1,080 mcg of (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)991 mcg DFE248%
Vitamin B12as Methylcobalamin1,000 mcg41,667%Vitamin B12 in Folate Methylation against 14,425 products1,000 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg1,000 mcg

Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg).

BiotinBiotin Note: USP1,000 mcg3,333%Biotin in Folate Methylation against 9,447 products1,000 mcg per serving; the middle half of products list 50 mcg to 300 mcg, the median 200 mcg.DV 30 mcg1,000 mcg

Higher than 84% of 9,447 products listing biotin (median 200 mcg).

Pantothenic Acidas D-Calcium Pantothenate, Vitamin B550 mg1,000%Pantothenic Acid (Vitamin B5) in Folate Methylation against 10,060 products50 mg per serving; the middle half of products list 6 mg to 50 mg, the median 12 mg.DV 5 mg50 mg

Higher than 72% of 10,060 products listing pantothenic acid (vitamin B5) (median 12 mg).

Choline3 mg1%Choline in Folate Methylation against 4,738 products3 mg per serving; the middle half of products list 18 mg to 100 mg, the median 40 mg.DV 550 mgUL 3,500 mg3 mg

92% of 4,738 products listing choline give more (median 40 mg).

Phosphatidylcholine50 mgPhosphatidylcholine in Folate Methylation against 403 products50 mg per serving; the middle half of products list 35 mg to 420 mg, the median 120 mg.50 mg

66% of 403 products listing phosphatidylcholine give more (median 120 mg).

Zincas Zinc Aspartate, Zinc Oxide, Zinc Rice ChelateZinc (Form: as Zinc Aspartate, Zinc Oxide)2 mg14%Zinc in Folate Methylation against 13,186 products2 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg2 mg

90% of 13,186 products listing zinc give more (median 11 mg).

Trimethylglycine500 mgBetaine in Folate Methylation against 731 products500 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.500 mg

Higher than 55% of 731 products listing betaine (median 250 mg).

Phosphatidylserineas Soybean Extract20% Extract100 mgPhosphatidylserine in Folate Methylation against 641 products100 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.100 mg

29% of 641 products listing phosphatidylserine give more (median 100 mg).

Source: NIH ODS Dietary Supplement Label Database, label 277360 (entered November 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 50 mg of niacin, 1.4 times the adult Tolerable Upper Intake Level.
  • 92% of the 4,738 products that print an amount of choline list more than its 3 mg of choline (median 40 mg).
  • 90% of the 13,186 products that print an amount of zinc list more than its 2 mg of zinc (median 11 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Folate Methylation's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Warnings
Warning: If you are pregnant or breast feeding, consult your physician before using this product.
Recommendations: Take two (2) capsules daily, or as directed by your physician.
Keep out of reach of children.
Contains: Soy (phosphatidylcholine, phosphatidylserine)
Allergens and what it does not contain
Contains no preservatives.
Storage
Keep container tightly closed, store in a cool, dry place.

Source: label statements in DSLD label 277360.

What else is on the label?

Other ingredients: Rice Chelate, Silicon Dioxide, Sodium Sulfate, Hypromellose, Water, Purified.

How many labels does Folate Methylation have?

2 labels are on file under this name since September 25, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 277360 (current) Entered November 22, 2022 · on the market · 60 vegetarian capsules · UPC 8 15354 02055 6
  2. Label 235735 Entered September 25, 2020 · off the market March 16, 2022 · 60 vegetarian capsules · UPC 8 15354 02055 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Priority One Nutritional Supplements, Inc. (distributor). All Priority One Nutritional Supplements products.

Where next?