PlainVitamins

EstroFactors

by Metagenics · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 7 55571 95222 6
  • DSLD label 295678
  • Serving 2 vegetarian capsules
  • 30 servings

EstroFactors by Metagenics lists 20 ingredients, 14 with an amount per serving of 2 vegetarian capsules, such as 750 mcg of vitamin A, 36.2 mg of vitamin E, 1 mg of riboflavin and 50 mg of vitamin B6; 6 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on September 25, 2023.

What is in EstroFactors?

Each row as the label prints it, per serving of 2 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

EstroFactors: Supplement Facts rows against the market (DSLD label 295678, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Aas Mixed Carotenoids750 mcg83%
Vitamin Eas D-Alpha Tocopheryl Polyethylene Glycol 1000 Succinate, D-Alpha Tocopheryl Succinate36.2 mg241%
Riboflavin1 mg77%Riboflavin in EstroFactors against 9,824 products1 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg1 mg

84% of 9,824 products listing riboflavin give more (median 4 mg). Per day at the most servings: 2 mg.

Vitamin B6as Pyridoxine Hydrochloride50 mg2,941%Vitamin B6 in EstroFactors against 15,277 products50 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg50 mg

Higher than 87% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 100 mg.

Folateas Metafolin340 mcg DFE85%
Vitamin B12as Methylcobalamin30 mcg1,250%Vitamin B12 in EstroFactors against 14,425 products30 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg30 mcg

51% of 14,425 products listing vitamin B12 give more (median 36 mcg). Per day at the most servings: 60 mcg.

Rice Protein Matrix and Polyphenolsas Hops (Humulus lupulus L.) cone extract250 mg
BioResponse DIMDiindolylmethane (DIM) Complex150 mg
Starchin the blend, no amount given
Diindolylmethane37.5 mgDiindolylmethane in EstroFactors against 425 products37.5 mg per serving; the middle half of products list 100 mg to 200 mg, the median 100 mg.37.5 mg

88% of 425 products listing diindolylmethane give more (median 100 mg). Per day at the most servings: 75 mg.

D-Alpha-Tocopheryl Polyethylene Glycol 1000 Succinatein the blend, no amount given
Phosphatidylcholineas Sunflowerin the blend, no amount given
Silicain the blend, no amount given
Green Tea Leaf ExtractDecaffeinated100 mgGreen Tea in EstroFactors against 2,595 products100 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.100 mg

46% of 2,595 products listing green tea give more (median 100 mg). Per day at the most servings: 200 mg.

CatechinsStandardized to 60% catechins60 mgCatechin in EstroFactors against 108 products60 mg per serving; the middle half of products list 45 mg to 150 mg, the median 85 mg.60 mg

66% of 108 products listing catechin give more (median 85 mg). Per day at the most servings: 120 mg.

Epigallocatechin GallateStandardized to 40% epigallocatechin gallate40 mgEGCG in EstroFactors against 291 products40 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.40 mg

80% of 291 products listing EGCG give more (median 100 mg). Per day at the most servings: 80 mg.

N-Acetyl-L-Cysteine50 mgN-Acetyl Cysteine in EstroFactors against 1,259 products50 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.50 mg

75% of 1,259 products listing N-acetyl cysteine give more (median 150 mg). Per day at the most servings: 100 mg.

7-Hydroxymatairesinol (HMR) Potassium Acetate Complex50 mg
Proprietary Mix50 mg
Curcuminas Curcuma longa Rhizome Extractin the blend, no amount given
Curcuminoidsstandardized to 40% curcuminoids20 mgCurcuminoid in EstroFactors against 309 products20 mg per serving; the middle half of products list 40 mg to 300 mg, the median 100 mg.20 mg

91% of 309 products listing curcuminoid give more (median 100 mg). Per day at the most servings: 40 mg.

Galactomannanas Fenugreek Seed Extractin the blend, no amount given
Mixed Carotenoidsas Alpha-Carotene, Beta-Carotene, Cryptoxanthin1.8 mgCarotenoids in EstroFactors against 261 products1.8 mg per serving; the middle half of products list 0.5 mg to 10 mg, the median 4 mg.1.8 mg

67% of 261 products listing carotenoids give more (median 4 mg). Per day at the most servings: 3.6 mg.

Source: NIH ODS Dietary Supplement Label Database, label 295678 (entered September 25, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 91% of the 309 products that print an amount of curcuminoid list more than its 20 mg of curcuminoid (median 100 mg).

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take two capsules once or twice daily or as directed by your healthcare practitioner.
Warnings
Warning: Do not use if pregnant or breastfeeding. Caution: Consult your healthcare practitioner before use if you are taking medications, including birth-control.
Keep out of reach of children.
Tamper Evident: Do not use if safety seal is missing or broken.
Practitioner Exclusive
Allergens and what it does not contain
This product is non-GMO and gluten-free.
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
Storage
Storage: Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 295678.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Chlorophyllin, Gellan Gum, Magnesium Stearate, Silica.

How many labels does EstroFactors have?

5 labels are on file under this name since October 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 295678 (current) Entered September 25, 2023 · on the market · 60 vegetarian capsules · UPC 7 55571 95222 6
  2. Label 216361 Entered March 24, 2020 · off the market September 7, 2022 · 60 capsules · UPC 7 55571 95222 6
  3. Label 210903 Entered January 25, 2020 · off the market December 20, 2019 · 60 capsules
  4. Label 26822 Entered October 25, 2013 · on the market · 180 tablets · UPC 7 55571 91025 7
  5. Label 26818 Entered October 25, 2013 · on the market · 90 tablets · UPC 7 55571 01585 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Metagenics (manufacturer), Gig Harbor, WA. All Metagenics products.

Where next?