Endothelial Defense
by Life Extension · softgel capsule · 60 softgels
- Off the market since April 2016 (NIH)
- UPC 7 37870 19976 2
- DSLD label 63438
- Serving 2 softgels
- 30 servings
Endothelial Defense by Life Extension lists 4 ingredients, 4 with an amount per serving of 2 softgels, such as 400 mg of pomella pomegranate extract, 100 mg of pomegranate 5:1 extract, 137.5 mg of proprietary pomegranate blend and 500 mg of cordiart flavonoid glycoside. Its current label entered the NIH Dietary Supplement Label Database on August 24, 2016.
What is in Endothelial Defense?
Each row as the label prints it, per serving of 2 softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Superoxide Dismutase/Gliadin Complexas Superoxide Dismutase | 500 mg | ||
| Pomella Pomegranate extractas PunicalaginsPomella Pomegranate extract (Form: std. to 30% Punicalagins Note: 120 mg) PlantPart: fruit | 400 mg | Higher than 93% of 860 products listing pomegranate (median 70.5 mg). | |
| Pomegranate 5:1 extract | 100 mg | ||
| Proprietary Pomegranate Blendas Punicic AcidProprietary Pomegranate Blend (Form: std. to 22% Punicic Acid Note: 30 mg) PlantPart: flower extract and seed oil | 137.5 mg | ||
| Cordiart Flavonoid Glycosideas Immature Sweet OrangeCordiart Flavonoid Glycoside (Form: from Immature Sweet Orange (Form: std. to 90% Rutinoside) PlantPart: peel) | 500 mg | Higher than 94% of 2,343 products listing flavonoid (median 50 mg). |
Source: NIH ODS Dietary Supplement Label Database, label 63438 (entered August 24, 2016), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- Its 637.5 mg of pomella pomegranate extract (filed by NIH under pomegranate) (3 rows of the label added together) is higher than 93% of the 860 pomegranate products that print an amount; 54 list more.
- Its 500 mg of cordiart flavonoid glycoside (filed by NIH under flavonoid) is higher than 94% of the 2,343 flavonoid products that print an amount; 65 list more.
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
3 products list the very same ingredients; the nearest amounts come first.
- Endothelial Defense With Pomegranate Complete And CordiartLife Extension same ingredients
- Endothelial Defense With Full-Spectrum Pomegranate And CordiartLife Extension · off the market same ingredients
- Pomegranate Fruit Extract 250 mgBasic Organics same ingredients
- Endothelial Defense Pomegranate CompleteLife Extension 2 shared, 55% alike
- PomegranateGNC Herbal Plus Standardized 1 shared, 51% alike
- PomActiv Forte Pomegranate Extract 200 mgVitamer Laboratories 1 shared, 51% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Read the entire label and follow the directions carefully prior to use. Directions: Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.
- Warnings
- Caution: Do not take this product if you are allergic to wheat or gluten.
- WARNING: -Keep out of reach of children.
- DO NOT EXCEED RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged .
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
- Contains wheat.
- Allergens and what it does not contain
- Non-GMO
- Storage
- Store tightly closed in a cool, dry place.
Source: label statements in DSLD label 63438.
What else is on the label?
Other ingredients: extra virgin Olive Oil, Gelatin, Maltodextrin, Glycerin, purified Water, Sunflower Lecithin, Carob color, Beeswax.
How many labels does Endothelial Defense have?
2 labels are on file under this name since July 25, 2016: other sizes, label designs and reformulations. The current one leads this page.
- Label 63438 (current) Entered August 24, 2016 · off the market April 1, 2016 · 60 softgels · UPC 7 37870 19976 2
- Label 62500 Entered July 25, 2016 · off the market November 4, 2016 · 60 softgels · UPC 7 37870 19976 2
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.