Optimized TryptoPure Plus

by Life Extension · capsule · 90 Vegetarian Capsules

  • On the market (NIH)
  • UPC 7 37870 12029 2
  • DSLD label 2511
  • Serving 1 to 3 vegetarian capsules; amounts per 3 vegetarian capsules
  • 30 servings

Optimized TryptoPure Plus by Life Extension lists 5 ingredients, 3 with an amount per serving of 3 vegetarian capsules, such as 66 mg of niacin, 1,000 mg of TryptoPure L-tryptophan and 250 mg of L-lysine; 2 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on November 25, 2011.

What is in Optimized TryptoPure Plus?

Each row as the label prints it, per serving of 3 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Optimized TryptoPure Plus: Supplement Facts rows against the market (DSLD label 2511, January 2026 release)
IngredientAmount% DVAmong products listing it
Niacinas Niacinamide, Vitamin B3Niacin (Form: Vitamin B-3, as Niacinamide)66 mg330%Niacin in Optimized TryptoPure Plus against 12,413 products66 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg66 mg

Higher than 85% of 12,413 products listing niacin (median 20 mg). 1.9 times the adult UL a day.

TryptoPure L-Tryptophanas L-TryptophanTryptoPure L-Tryptophan (Form: 1% pure USP pharmaceutical-grade L-Tryptophan)1,000 mgTryptophan in Optimized TryptoPure Plus against 605 products1,000 mg per serving; the middle half of products list 55 mg to 471 mg, the median 123 mg.1,000 mg

Higher than 92% of 605 products listing tryptophan (median 123 mg).

L-Lysineas L-Lysine MonohydrochlorideL-Lysine (Form: from USP pharmaceutical-grade AjiPure L-Lysine HCl)250 mgLysine in Optimized TryptoPure Plus against 1,250 products250 mg per serving; the middle half of products list 148.25 mg to 996.25 mg, the median 500 mg.250 mg

63% of 1,250 products listing lysine give more (median 500 mg).

Proprietary TryptoPure Plus Blend (Herb/Botanical)285 mg
Perluxan Hops standardized extractin the blend, no amount given
Ginger root standardized extractin the blend, no amount given
Ursole Rosemary standardized extractin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 2511 (entered November 25, 2011), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 66 mg of niacin, 1.9 times the adult Tolerable Upper Intake Level.
  • Its 1,000 mg of TryptoPure L-tryptophan (filed by NIH under tryptophan) is higher than 92% of the 605 tryptophan products that print an amount; 20 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Optimized TryptoPure Plus's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
DIRECTIONS: Take 2-3 capsules all at once before bedtime, or one capsule on an empty stomach before each meal, or as recommended by a healthcare practitioner. For maximum absorption take with a small amount of carbohydrate, such as diluted juice.
Take separately from food or supplements containing protein or amino acids, especially arginine.
Warnings
WARNINGS: - KEEP OUT OF REACH OF CHILDREN.
Contains corn and rice.
- DO NOT EXCEED RECOMMENDED DOSE.
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition.
CAUTION: Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms. Do not take L-tryptophan in combination with other agents that increase serotonin levels in the central nervous system. Agents that increase serotonin levels can include psychiatric medications (e.g. antidepressants, lithium), migraine medications (e.g. sumatriptan), Parkinson’s disease medications (e.g. carbidopa), and dextromethorphan, an over-the-counter cough suppressant. Do not use before driving or operating heavy machinery.
Allergens and what it does not contain
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 2511.

What else is on the label?

Other ingredients: Vegetable Cellulose, Magnesium Stearate, Maltodextrin, Rice Flour, modified Food Starch, Silica.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): AJIPURE(TM) AMINO ACIDS.

How many labels does Optimized TryptoPure Plus have?

One label is on file, entered on November 25, 2011.

  1. Label 2511 (current) Entered November 25, 2011 · on the market · 90 Vegetarian Capsules · UPC 7 37870 12029 2

DSLD also links this label to: Optimized Tryptophan Plus (image difference, same product), Optimized Tryptophan Plus (image difference, same product), Optimized Tryptophan Plus (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (manufacturer), Ft. Lauderdale, FL. All Life Extension products.

Where next?