Optimized Resveratrol with Nicotinamide Riboside

by Life Extension · capsule · 30 vegetarian capsules

  • On the market (NIH)
  • UPC 7 37870 20313 1
  • DSLD label 60754
  • Serving 1 vegetarian capsule

Optimized Resveratrol with Nicotinamide Riboside by Life Extension lists 5 ingredients, 5 with an amount per serving of 1 vegetarian capsule, such as 250 mg of trans-resveratrol, 150 mg of quercetin, 100 mg of NIAGEN nicotinamide riboside and 10 mg of fisetin. Its current label entered the NIH Dietary Supplement Label Database on June 24, 2016.

What is in Optimized Resveratrol with Nicotinamide Riboside?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Optimized Resveratrol with Nicotinamide Riboside: Supplement Facts rows against the market (DSLD label 60754, January 2026 release)
IngredientAmount% DVAmong products listing it
Trans-Resveratrolas Japanese KnotweedTrans-Resveratrol (Form: from Japanese Knotweed PlantPart: root)250 mgResveratrol in Optimized Resveratrol with Nicotinamide Riboside against 1,123 products250 mg per serving; the middle half of products list 20 mg to 125 mg, the median 50 mg.250 mg

Higher than 85% of 1,123 products listing resveratrol (median 50 mg).

Quercetinas Quercetin DihydrateQuercetin (Form: as Quercetin Dihydrate)150 mgQuercetin in Optimized Resveratrol with Nicotinamide Riboside against 1,548 products150 mg per serving; the middle half of products list 26.5 mg to 250 mg, the median 100 mg.150 mg

Higher than 63% of 1,548 products listing quercetin (median 100 mg).

NIAGEN Nicotinamide Riboside100 mg625%*Niacin in Optimized Resveratrol with Nicotinamide Riboside against 12,413 products100 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg100 mg

Higher than 88% of 12,413 products listing niacin (median 20 mg). 2.9 times the adult UL a day.

Red Grape (fruit) and Wild Blueberry (fruit) blendas Anthocyanins, OPCs, PolyphenolsRed Grape (fruit) and Wild Blueberry (fruit) blend (Form: Polyphenols, Anthocyanins, OPCs) PlantPart: fruit Note: providing40 mg
Fisetinas Wax tree extractFisetin (Form: from Wax tree extract) PlantPart: stem10 mgFisetin in Optimized Resveratrol with Nicotinamide Riboside against 48 products10 mg per serving; the middle half of products list 29.5 mg to 100 mg, the median 100 mg.10 mg

79% of 48 products listing fisetin give more (median 100 mg).

Trans-Pterostilbeneas pTeroPureTrans-Pterostilbene (Form: from pTeroPure)0.5 mgPterostilbene in Optimized Resveratrol with Nicotinamide Riboside against 115 products0.5 mg per serving; the middle half of products list 10 mg to 83 mg, the median 50 mg.0.5 mg

85% of 115 products listing pterostilbene give more (median 50 mg).

* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.

Source: NIH ODS Dietary Supplement Label Database, label 60754 (entered June 24, 2016), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 100 mg of niacin, 2.9 times the adult Tolerable Upper Intake Level.
  • 79% of the 48 products that print an amount of fisetin list more than its 10 mg of fisetin (median 100 mg).
  • 85% of the 115 products that print an amount of pterostilbene list more than its 0.5 mg of trans-pterostilbene (filed by NIH under pterostilbene) (median 50 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Optimized Resveratrol with Nicotinamide Riboside's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.
Warnings
CAUTION: If you are taking anti-coagulant or anti-platelet medications, or have bleeding disorder, consult your healthcare provider before taking this product.
WARNINGS: -Keep out of reach of children.
-Do not exceed recommended dose. -Do not purchase if outer seal is broken or damaged.
-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Allergens and what it does not contain
Non-GMO
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 60754.

What else is on the label?

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Silica, Vegetable Stearate, Maltodextrin.

How many labels does Optimized Resveratrol with Nicotinamide Riboside have?

One label is on file, entered on June 24, 2016.

  1. Label 60754 (current) Entered June 24, 2016 · on the market · 30 vegetarian capsules · UPC 7 37870 20313 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?