SeroPlus

by Pure Encapsulations · capsule · 60 capsules

  • On the market (NIH)
  • UPC 7 66298 02408 0
  • DSLD label 299753
  • Serving 2 capsules
  • 30 servings

SeroPlus by Pure Encapsulations lists 10 ingredients, 10 with an amount per serving of 2 capsules, such as 100 mg of vitamin C, 20 mg of niacin, 6.7 mg of vitamin B6 and 833 mcg DFE of folate. Its current label entered the NIH Dietary Supplement Label Database on December 14, 2023.

What is in SeroPlus?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

SeroPlus: Supplement Facts rows against the market (DSLD label 299753, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas Ascorbic Acid100 mg111%Vitamin C in SeroPlus against 18,583 products100 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg100 mg

50% of 18,583 products listing vitamin C give more (median 100 mg). Per day at the most servings: 200 mg.

Niacinas Niacinamide20 mg125%Niacin in SeroPlus against 12,413 products20 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg20 mg

46% of 12,413 products listing niacin give more (median 20 mg). Per day at the most servings: 40 mg. 1.1 times the adult UL a day.

Vitamin B6as Pyridoxal 5-Phosphate6.7 mg394%Vitamin B6 in SeroPlus against 15,277 products6.7 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg6.7 mg

Higher than 51% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 13.4 mg.

Folateas Metafolin833 mcg DFE208%
L-5-Methyltetrahydrofolate500 mcg
Magnesiumas Dimagnesium Malate100 mg24%Magnesium in SeroPlus against 14,003 products100 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg100 mg

Higher than 51% of 14,003 products listing magnesium (median 86 mg). Per day at the most servings: 200 mg.

Zincas Zinc Picolinate10 mg91%Zinc in SeroPlus against 13,186 products10 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg10 mg

51% of 13,186 products listing zinc give more (median 11 mg). Per day at the most servings: 20 mg.

5-Hydroxytryptophan100 mg5-HTP in SeroPlus against 676 products100 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.100 mg

18% of 676 products listing 5-HTP give more (median 100 mg). Per day at the most servings: 200 mg.

Inositolas Myo-Inositol500 mgInositol in SeroPlus against 4,042 products500 mg per serving; the middle half of products list 10 mg to 80 mg, the median 30 mg.500 mg

Higher than 93% of 4,042 products listing inositol (median 30 mg). Per day at the most servings: 1,000 mg.

Taurinefree-form200 mgTaurine in SeroPlus against 2,337 products200 mg per serving; the middle half of products list 110 mg to 1,000 mg, the median 500 mg.200 mg

65% of 2,337 products listing taurine give more (median 500 mg). Per day at the most servings: 400 mg.

Source: NIH ODS Dietary Supplement Label Database, label 299753 (entered December 14, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 2 servings a day, the most its directions give, the label lists 40 mg of niacin, 1.1 times the adult Tolerable Upper Intake Level.
  • Its 500 mg of inositol is higher than 93% of the 4,042 inositol products that print an amount; 199 list more.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with SeroPlus's, rare ingredients counting for more.

  • CerenityOrtho Molecular Products 9 shared, 69% alike
  • Calm+Revive 9 shared, 69% alike
  • Cerenity PMOrtho Molecular Products 8 shared, 59% alike
  • MetaCalmMetabolic Maintenance 8 shared, 58% alike
  • TravaCorNS NeuroScience 7 shared, 57% alike
  • 5 - HTP 200 mgProtocol For Life Balance · off the market 5 shared, 56% alike

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendations: As a dietary supplement, take 2 capsules, 1-2 times daily, between meals.
Warnings
Warning: Not to be taken by pregnant or lactating women. If you have any health conditions or are taking medication, particularly psychiatric medications, consult your healthcare professional before use. Do not use concurrently with antidepressants.
Keep out of the reach of children.
Use only if safety seal is intact.
Allergens and what it does not contain
Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org Gluten-Free, Non-GMO & Hypoallergenic
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 299753.

What else is on the label?

Other ingredients: Cellulose, Water.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GFCO.org (Gluten-Free Certification Organization). Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does SeroPlus have?

3 labels are on file under this name since November 21, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 299753 (current) Entered December 14, 2023 · on the market · 60 capsules · UPC 7 66298 02408 0
  2. Label 219190 Entered May 22, 2020 · off the market October 29, 2018 · 120 capsules · UPC 7 66298 01453 1
  3. Label 183280 Entered November 21, 2018 · on the market · 120 capsules · UPC 7 66298 01453 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Pure Encapsulations (manufacturer). All Pure Encapsulations products.

Where next?