Ortho Sleep

by AOR Advanced Orthomolecular Research Advanced · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 6 24917 08186 2
  • DSLD label 214855
  • Serving 2 capsules
  • 30 servings

Ortho Sleep by AOR Advanced Orthomolecular Research Advanced lists 7 ingredients, 7 with an amount per serving of 2 capsules, such as 300 mg of lemon balm (melissa officinalis L.) aerial parts extract, 200 mg of L-theanine, 150 mg of valerian (valeriana officinalis L.) root extract and 100 mg of GABA. Its current label entered the NIH Dietary Supplement Label Database on March 24, 2020.

What is in Ortho Sleep?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Ortho Sleep: Supplement Facts rows against the market (DSLD label 214855, January 2026 release)
IngredientAmount% DVAmong products listing it
Lemon Balm (Melissa officinalis L.) aerial parts extract300 mgLemon balm in Ortho Sleep against 475 products300 mg per serving; the middle half of products list 50 mg to 200 mg, the median 100 mg.300 mg

Higher than 77% of 475 products listing lemon balm (median 100 mg).

L-Theanine200 mgTheanine in Ortho Sleep against 1,602 products200 mg per serving; the middle half of products list 90 mg to 200 mg, the median 100 mg.200 mg

Higher than 61% of 1,602 products listing theanine (median 100 mg).

Valerian (Valeriana officinalis L.) root extract150 mgValerian in Ortho Sleep against 647 products150 mg per serving; the middle half of products list 80 mg to 450 mg, the median 200 mg.150 mg

54% of 647 products listing valerian give more (median 200 mg).

GABA100 mgGABA in Ortho Sleep against 744 products100 mg per serving; the middle half of products list 80 mg to 400 mg, the median 100 mg.100 mg

48% of 744 products listing GABA give more (median 100 mg).

L-5-Hydroxytryptophanas GriffoniaL-5-Hydroxytryptophan (Form: from Griffonia PlantPart: seed)100 mg5-HTP in Ortho Sleep against 676 products100 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.100 mg

18% of 676 products listing 5-HTP give more (median 100 mg).

Passionflower (Passiflora incarnata L.) aerial parts extract32 mgPassionflower in Ortho Sleep against 562 products32 mg per serving; the middle half of products list 40 mg to 200 mg, the median 100 mg.32 mg

78% of 562 products listing passionflower give more (median 100 mg).

Melatonin3 mgMelatonin in Ortho Sleep against 1,557 products3 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.3 mg

38% of 1,557 products listing melatonin give more (median 3 mg).

Source: NIH ODS Dietary Supplement Label Database, label 214855 (entered March 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Ortho Sleep's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take 2 capsules before bedtime with/without food or as directed by a qualified health care practitioner.
Warnings
Do not use if safety seal is broken
Warning: Do not use if pregnant or breastfeeding. Consult a health care practitioner prior to use if you have a medical condition or if you’re using other medications.
Keep out of reach of children.
Caution: Do not drive or use machinery for 5 hours after taking Ortho Sleep, exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Hypersensitivity (e.g. allergy) has been known to occur, in which case, discontinue use and consult a healthcare provider.
To report a serious adverse event or obtain product information, call 1-866-215-0450
Allergens and what it does not contain
Non-GMO Gluten free
Made without wheat, gluten, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.
Storage
Store tightly sealed in a cool, dry place

Source: label statements in DSLD label 214855.

What else is on the label?

Other ingredients: Capsule, Maltodextrin, Silicon Dioxide, Gum Arabic, Sodium Stearyl Fumarate.

How many labels does Ortho Sleep have?

One label is on file, entered on March 24, 2020.

  1. Label 214855 (current) Entered March 24, 2020 · on the market · 60 vegetarian capsules · UPC 6 24917 08186 2

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names AOR Inc. (manufacturer), Clifton, NJ. All AOR Advanced Orthomolecular Research Advanced products.

Where next?