One Daily Essential

by 21st Century · tablet or pill · 100 tablets

  • On the market (NIH)
  • UPC 7 40985 27303 6
  • DSLD label 258543
  • Serving 1 tablet
  • 100 servings

One Daily Essential by 21st Century lists 13 ingredients, 13 with an amount per serving of 1 tablet, such as 900 mcg of vitamin A, 60 mg of vitamin C, 10 mcg (400 IU) of vitamin D3 and 13.5 mg of vitamin E. Its current label entered the NIH Dietary Supplement Label Database on January 22, 2022.

What is in One Daily Essential?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

One Daily Essential: Supplement Facts rows against the market (DSLD label 258543, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Aas Beta-Carotene, Vitamin A Acetateas Vitamin A Acetate, and as 17% Beta-Carotene900 mcg100%
Vitamin Cas Ascorbic Acid60 mg67%Vitamin C in One Daily Essential against 18,583 products60 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg60 mg

65% of 18,583 products listing vitamin C give more (median 100 mg).

Vitamin D3as Cholecalciferol400 IU10 mcg (400 IU)50%Vitamin D in One Daily Essential against 14,175 products10 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg10 mcg

57% of 14,175 products listing vitamin D give more (median 15 mcg).

Vitamin Eas DL-Alpha-Tocopheryl Acetate13.5 mg90%
Thiamineas Thiamine Mononitrate, Vitamin B11.5 mg125%Thiamin in One Daily Essential against 9,830 products1.5 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg1.5 mg

66% of 9,830 products listing thiamin give more (median 5 mg).

Riboflavinas Vitamin B21.7 mg131%Riboflavin in One Daily Essential against 9,824 products1.7 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg1.7 mg

64% of 9,824 products listing riboflavin give more (median 4 mg).

Niacinas Niacinamide20 mg125%Niacin in One Daily Essential against 12,413 products20 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg20 mg

46% of 12,413 products listing niacin give more (median 20 mg).

Vitamin B6as Pyridoxine Hydrochloride2 mg118%Vitamin B6 in One Daily Essential against 15,277 products2 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg2 mg

69% of 15,277 products listing vitamin B6 give more (median 6 mg).

Folate667 mcg DFE167%
Folic Acid400 mcg
Vitamin B12as Cyanocobalamin6 mcg250%Vitamin B12 in One Daily Essential against 14,425 products6 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg6 mcg

74% of 14,425 products listing vitamin B12 give more (median 36 mcg).

Pantothenic Acidas D-Calcium Pantothenate10 mg200%Pantothenic Acid (Vitamin B5) in One Daily Essential against 10,060 products10 mg per serving; the middle half of products list 6 mg to 50 mg, the median 12 mg.DV 5 mg10 mg

52% of 10,060 products listing pantothenic acid (vitamin B5) give more (median 12 mg).

Calciumas Calcium Carbonate, Dicalcium Phosphate93 mg7%Calcium in One Daily Essential against 17,831 products93 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg93 mg

59% of 17,831 products listing calcium give more (median 115 mg).

Source: NIH ODS Dietary Supplement Label Database, label 258543 (entered January 22, 2022), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take one (1) tablet daily with any meal or as directed by your healthcare provider. Do not exceed recommended dosage.
Warnings
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Allergens and what it does not contain
Gluten free
No added Yeast or Artificial Flavors. Gluten free.
Storage
Store at room temperature.

Source: label statements in DSLD label 258543.

What else is on the label?

Other ingredients: Cellulose, Starch, Gelatin, Stearic Acid, Croscarmellose Sodium, Artificial Colors, Magnesium Silicate, Magnesium Stearate, Maltodextrin, PEG, Polyvinyl alcohol, Silicon Dioxide, Titanium Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed quality Laboratory tested.

How many labels does One Daily Essential have?

4 labels are on file under this name since July 25, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 258543 (current) Entered January 22, 2022 · on the market · 100 tablets · UPC 7 40985 27303 6
  2. Label 233580 Entered November 21, 2020 · off the market August 5, 2020 · 100 tablets · UPC 7 40985 27303 6
  3. Label 207422 Entered September 24, 2019 · off the market August 6, 2021 · 100 tablets · UPC 7 40985 27303 6
  4. Label 11556 Entered July 25, 2012 · on the market · 100 tablets · UPC 7 40985 22660 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?