Natural Changes

by Nature's Sunshine · other (e.g. tea bag) · 42 packets

  • On the market (NIH)
  • DSLD label 334374
  • Serving 1 packet (Natural Changes Packet- 4 capsules, 2 tablets)
  • 42 servings

Natural Changes by Nature's Sunshine lists 52 ingredients, 23 with an amount per serving of 1 packet, such as 37.5 mcg of vitamin A, 437.5 mg of vitamin C, 1.25 mcg (50 IU) of vitamin D3 and 20 mg of thiamine; 29 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on September 25, 2025.

What is in Natural Changes?

Each row as the label prints it, per serving of 1 packet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Natural Changes: Supplement Facts rows against the market (DSLD label 334374, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Aas Beta-Carotene37.5 mcg4%
Vitamin Cas Ascorbic Acid437.5 mg486%Vitamin C in Natural Changes against 18,583 products437.5 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg437.5 mg

Higher than 80% of 18,583 products listing vitamin C (median 100 mg). Per day at the most servings: 875 mg.

Vitamin D3as Cholecalciferol1.25 mcg (50 IU)6%Vitamin D in Natural Changes against 14,175 products1.25 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg1.25 mcg

97% of 14,175 products listing vitamin D give more (median 15 mcg). Per day at the most servings: 2.5 mcg.

Thiamineas Thiamine Mononitrate, Vitamin B120 mg1,061%Thiamin in Natural Changes against 9,830 products20 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg20 mg

Higher than 69% of 9,830 products listing thiamin (median 5 mg). Per day at the most servings: 40 mg.

Riboflavinas Vitamin B220 mg1,538%Riboflavin in Natural Changes against 9,824 products20 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg20 mg

Higher than 72% of 9,824 products listing riboflavin (median 4 mg). Per day at the most servings: 40 mg.

Niacinas Niacinamide40 mg250%Niacin in Natural Changes against 12,413 products40 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg40 mg

Higher than 71% of 12,413 products listing niacin (median 20 mg). Per day at the most servings: 80 mg. 2.3 times the adult UL a day.

Vitamin B6as Pyridoxine Hydrochloride21.25 mg1,250%Vitamin B6 in Natural Changes against 15,277 products21.25 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg21.25 mg

Higher than 75% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 42.5 mg.

Folate206 mcg DFE52%
Folic Acid125 mcg
Vitamin B12as Cyanocobalamin41.5 mcg1,729%Vitamin B12 in Natural Changes against 14,425 products41.5 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg41.5 mcg

Higher than 51% of 14,425 products listing vitamin B12 (median 36 mcg). Per day at the most servings: 83 mcg.

Biotin100 mcg333%Biotin in Natural Changes against 9,447 products100 mcg per serving; the middle half of products list 50 mcg to 300 mcg, the median 200 mcg.DV 30 mcg100 mcg

61% of 9,447 products listing biotin give more (median 200 mcg). Per day at the most servings: 200 mcg.

Pantothenic Acidas Calcium D-Pantothenate80 mg1,000%Pantothenic Acid (Vitamin B5) in Natural Changes against 10,060 products80 mg per serving; the middle half of products list 6 mg to 50 mg, the median 12 mg.DV 5 mg80 mg

Higher than 85% of 10,060 products listing pantothenic acid (vitamin B5) (median 12 mg). Per day at the most servings: 160 mg.

Cholineas Choline Bitartrate13 mg2%Choline in Natural Changes against 4,738 products13 mg per serving; the middle half of products list 18 mg to 100 mg, the median 40 mg.DV 550 mgUL 3,500 mg13 mg

78% of 4,738 products listing choline give more (median 40 mg). Per day at the most servings: 26 mg.

Calciumas Calcium Amino Acid Chelate, Calcium Citrate, Dicalcium Phosphate150 mg12%Calcium in Natural Changes against 17,831 products150 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg150 mg

Higher than 58% of 17,831 products listing calcium (median 115 mg). Per day at the most servings: 300 mg.

Ironas Ferrous Gluconate6.75 mg4%

This amount is far outside what other labels list for iron, or disagrees with the label's own %DV: possibly a unit or transcription slip in the database. Check the label image on DSLD.

Phosphorusas Dicalcium Phosphate47 mg4%Phosphorus in Natural Changes against 3,786 products47 mg per serving; the middle half of products list 45 mg to 200 mg, the median 90 mg.DV 1,250 mgUL 4,000 mg47 mg

74% of 3,786 products listing phosphorus give more (median 90 mg). Per day at the most servings: 94 mg.

Magnesiumas Magnesium Amino Acid Chelate, Magnesium Oxide150 mg30%Magnesium in Natural Changes against 14,003 products150 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg150 mg

Higher than 70% of 14,003 products listing magnesium (median 86 mg). Per day at the most servings: 300 mg.

Zincas Zinc Oxide3.75 mg34%Zinc in Natural Changes against 13,186 products3.75 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg3.75 mg

82% of 13,186 products listing zinc give more (median 11 mg). Per day at the most servings: 7.5 mg.

Copperas Copper Gluconate0.5 mg56%Copper in Natural Changes against 6,468 products0.5 mg per serving; the middle half of products list 0.5 mg to 2 mg, the median 1 mg.DV 0.9 mgUL 10 mg0.5 mg

68% of 6,468 products listing copper give more (median 1 mg). Per day at the most servings: 1 mg.

Manganeseas Manganese Amino Acid Chelate6.25 mg11%

This amount is far outside what other labels list for manganese, or disagrees with the label's own %DV: possibly a unit or transcription slip in the database. Check the label image on DSLD.

Potassiumas Potassium Gluconate25 mg1%Potassium in Natural Changes against 11,614 products25 mg per serving; the middle half of products list 50 mg to 190 mg, the median 99 mg.DV 4,700 mg25 mg

86% of 11,614 products listing potassium give more (median 99 mg). Per day at the most servings: 50 mg.

Boronas Boron Amino Acid Chelate0.25 mgBoron in Natural Changes against 3,339 products0.25 mg per serving; the middle half of products list 0.3 mg to 2 mg, the median 1 mg.UL 20 mg0.25 mg

75% of 3,339 products listing boron give more (median 1 mg). Per day at the most servings: 0.5 mg.

C-X Proprietary Blend840 mg
Dong Quaiin the blend, no amount given
Blessed Thistlein the blend, no amount given
Licoricein the blend, no amount given
Eleutheroin the blend, no amount given
Sarsaparilla root extractin the blend, no amount given
Black Cohosh Rhizome, Root Extractas Actaea racemosa Rhizome Extract, Actaea racemosa Root Extractin the blend, no amount given
Squawvinein the blend, no amount given
False Unicornin the blend, no amount given
Wild Yam & Chaste Tree Proprietary Blend210 mg
Wild Yamin the blend, no amount given
Wild Yam Root Extractas Dioscorea villosa Root Extractin the blend, no amount given
Chaste Tree Berry Extractin the blend, no amount given
Super GLA Proprietary Blend1,080 mg
Evening Primrose Seed Oilas Oenothera biennis Seed Oilin the blend, no amount given
Black Currant Seed Oilin the blend, no amount given
Borage Seed Oilin the blend, no amount given
Gamma-Linolenic Acid130 mgGamma Linolenic Acid in Natural Changes against 740 products130 mg per serving; the middle half of products list 42 mg to 160 mg, the median 90 mg.130 mg

Higher than 67% of 740 products listing gamma linolenic acid (median 90 mg). Per day at the most servings: 260 mg.

Show the other 17 rows of the label
Natural Changes: rows 41 to 57
IngredientAmount% DVAmong products listing it
Skeletal Strength Proprietary Blend54 mg
Horsetail Stem, Strobilus Extractas Horsetail, Horsetailin the blend, no amount given
Papaya Fruit Concentratein the blend, no amount given
Parsleyin the blend, no amount given
Valerianin the blend, no amount given
Betaine Hydrochloridein the blend, no amount given
Pineapple Fruit Juice Concentratein the blend, no amount given
Licorice Root Extractas Glycyrrhiza glabra Root Extractin the blend, no amount given
Nutri-Calm Proprietary Blend140 mg
Schisandrain the blend, no amount given
Inositolin the blend, no amount given
Bee Pollenin the blend, no amount given
Para-Aminobenzoic Acidin the blend, no amount given
Lemon bioflavonoid extractin the blend, no amount given
Hops Flower Extractin the blend, no amount given
Passionflower Extractas Passiflora incarnata Flower Extractin the blend, no amount given
Valerian root extractin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 334374 (entered September 25, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 97% of the 14,175 products that print an amount of vitamin D list more than its 1.25 mcg (50 IU) of vitamin D (median 15 mcg (600 IU)).
  • At 2 servings a day, the most its directions give, the label lists 80 mg of niacin, 2.3 times the adult Tolerable Upper Intake Level.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended use: Take the contents of one Natural Changes packet with breakfast, and one with your evening meal. Follow this pattern for 21 days.
Warnings
Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
This carton was sealed for your protection. Do not use if seal is missing or damaged.

Source: label statements in DSLD label 334374.

What else is on the label?

Other ingredients: Gelatin, Glycerin, Water, Carob fruit extract, Caramel color, Gelatin, Water, Cellulose, Stearic Acid, Silicon Dioxide, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed Pure.

How many labels does Natural Changes have?

2 labels are on file under this name since January 25, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 334374 (current) Entered September 25, 2025 · on the market · 42 packets
  2. Label 212510 Entered January 25, 2020 · off the market November 18, 2024 · 42 packets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Sunshine Products, Inc. (manufacturer), Spanish Fork, UT. All Nature's Sunshine products.

Where next?