Methyl Folate Optimizer
by NuMedica · capsule · 60 vegetable capsules
- On the market (NIH)
- UPC 8 12527 01011 6
- DSLD label 323579
- Serving 2 capsules
- 30 servings
Methyl Folate Optimizer by NuMedica lists 7 ingredients, 7 with an amount per serving of 2 capsules, such as 150 mg NE of niacin, 25 mg of vitamin B6, 10,200 mcg DFE of folate and 1,000 mcg of vitamin B12. Its current label entered the NIH Dietary Supplement Label Database on January 23, 2025.
What is in Methyl Folate Optimizer?
Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Niacinas Niacinamide | 150 mg NE | 938% | Higher than 94% of 12,413 products listing niacin (median 20 mg). 4.3 times the adult UL a day. |
| Vitamin B6as Pyridoxal 5-Phosphate | 25 mg | 1,471% | Higher than 76% of 15,277 products listing vitamin B6 (median 6 mg). |
| Folate | 10,200 mcg DFE | 2,550% | |
| Folateas Quatrefolic5100 mcg DFE | 3,000 mcg | ||
| Folateas (6S)-5-Methyltetrahydrofolic Acid Calcium Salt5100 mcg DFE | 3,000 mcg | ||
| Vitamin B12as Methylcobalamin | 1,000 mcg | 41,667% | Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg). |
| AstraGinas Astragalus Root Extract, Panax notoginseng Root ExtractProprietary blend | 12.5 mg | ||
| BioPerineas Black Pepper Fruit Extract | 2 mg | 93% of 2,363 products listing black pepper give more (median 5 mg). |
Source: NIH ODS Dietary Supplement Label Database, label 323579 (entered January 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- At 1 serving a day, the most its directions give, the label lists 150 mg of niacin, 4.3 times the adult Tolerable Upper Intake Level.
- 93% of the 2,363 products that print an amount of black pepper list more than its 2 mg of BioPerine (filed by NIH under black pepper) (median 5 mg).
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with Methyl Folate Optimizer's, rare ingredients counting for more.
- Cardiotek-Rx TabletsS J Pharmaceuticals 4 shared, 62% alike
- Stress B Complex RXTaylor MD Formulations 5 shared, 55% alike
- Women's Elite Strawberry KiwiProMera Sports · off the market 5 shared, 48% alike
- Women's Elite MangoProMera Sports · off the market 5 shared, 48% alike
- Women's ElilteProMera Sports · off the market 5 shared, 48% alike
- Women's Elilte MangoProMera Sports · off the market 5 shared, 48% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Directions: Take two capsules once per day with a meal or as directed by your healthcare practitioner.
- Warnings
- Caution: Keep out of reach of children.
- Allergens and what it does not contain
- Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy. Sourced from non-GMO ingredients.
- Gluten-Free
- Storage
- Storage: Keep tightly closed in a cool, dry place.
Source: label statements in DSLD label 323579.
What else is on the label?
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Bamboo Silica.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): cGMP Third-Party Certified Facility.
How many labels does Methyl Folate Optimizer have?
3 labels are on file under this name since August 31, 2018: other sizes, label designs and reformulations. The current one leads this page.
- Label 323579 (current) Entered January 23, 2025 · on the market · 60 vegetable capsules · UPC 8 12527 01011 6
- Label 255721 Entered October 22, 2021 · off the market May 30, 2023 · 60 vegetable capsules · UPC 8 12527 01011 6
- Label 180180 Entered August 31, 2018 · off the market June 22, 2021 · 60 vegetable capsules · UPC 8 12527 01011 6
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names NuMedica LLC (distributor), Tulsa, OK. All NuMedica products.