Homocysteine Supreme

by Designs for Health · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 8 79452 00070 4
  • DSLD label 239497
  • Serving 2 capsules
  • 30 servings

Homocysteine Supreme by Designs for Health lists 7 ingredients, 7 with an amount per serving of 2 capsules, such as 30 mg of riboflavin, 10 mg of vitamin B-6, 3,400 mcg of folate and 1,000 mcg of vitamin B12. Its current label entered the NIH Dietary Supplement Label Database on November 21, 2020.

What is in Homocysteine Supreme?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Homocysteine Supreme: Supplement Facts rows against the market (DSLD label 239497, January 2026 release)
IngredientAmount% DVAmong products listing it
Riboflavinas Riboflavin 5-PhosphateRiboflavin (Form: as Riboflavin-5-Phosphate)30 mg2,308%Riboflavin in Homocysteine Supreme against 9,824 products30 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg30 mg

Higher than 82% of 9,824 products listing riboflavin (median 4 mg).

Vitamin B-6as Pyridoxal 5-PhosphateVitamin B-6 (Form: as Pyridoxal-5-Phosphate)10 mg588%Vitamin B6 in Homocysteine Supreme against 15,277 products10 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg10 mg

Higher than 55% of 15,277 products listing vitamin B6 (median 6 mg).

Folate3,400 mcg850%Folate in Homocysteine Supreme against 7,022 products3,400 mcg per serving; the middle half of products list 200 mcg to 400 mcg, the median 400 mcg.3,400 mcg

Higher than 99% of 7,022 products listing folate (median 400 mcg).

Quatrefolic (6S)-5-Methyltetrahydrofolate, Glucosamine Salt4,000 mcg5-methyltetrahydrofolate glucosamine in Homocysteine Supreme against 176 products4,000 mcg per serving; the middle half of products list 300 mcg to 800 mcg, the median 593 mcg.4,000 mcg

Higher than 93% of 176 products listing 5-methyltetrahydrofolate glucosamine (median 593 mcg).

Vitamin B12as MethylcobalaminVitamin B-12 (Form: as Methylcobalamin)1,000 mcg41,667%Vitamin B12 in Homocysteine Supreme against 14,425 products1,000 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg1,000 mcg

Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg).

Trimethylgylcine900 mgBetaine in Homocysteine Supreme against 731 products900 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.900 mg

Higher than 67% of 731 products listing betaine (median 250 mg).

N-Acetyl-Cysteine100 mgN-Acetyl Cysteine in Homocysteine Supreme against 1,259 products100 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.100 mg

57% of 1,259 products listing N-acetyl cysteine give more (median 150 mg).

Source: NIH ODS Dietary Supplement Label Database, label 239497 (entered November 21, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 3,400 mcg of folate is higher than 99% of the 7,022 folate products that print an amount; 93 list more.
  • Its 4,000 mcg of quatrefolic (6S)-5-methyltetrahydrofolate, glucosamine salt (filed by NIH under 5-methyltetrahydrofolate glucosamine) is higher than 93% of the 176 5-methyltetrahydrofolate glucosamine products that print an amount; 9 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Use: As a dietary supplement, take two capsules per day with meals, or as directed by your health care practitioner.
Warnings
Report any adverse reactions to 860-623-6314
For professional use only
Keep out of reach of children.
Allergens and what it does not contain
Does not contain gluten.
Made with non-GMO ingredients
Storage
Store at room temperature.

Source: label statements in DSLD label 239497.

What else is on the label?

Other ingredients: Cellulose, Microcrystalline Cellulose, Dicalcium Phosphate, Silicon Dioxide, Vegetable Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed GMP Compliant Products.

How many labels does Homocysteine Supreme have?

3 labels are on file under this name since June 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 239497 (current) Entered November 21, 2020 · on the market · 60 vegetarian capsules · UPC 8 79452 00070 4
  2. Label 23515 Entered July 25, 2013 · off the market October 7, 2019 · 60 vegetarian capsules · UPC 8 79452 00070 4
  3. Label 23173 Entered June 25, 2013 · on the market · 120 vegetarian capsules · UPC 8 79452 00273 9

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Designs for Health, Inc. (manufacturer), Suffield, CT. All Designs for Health products.

Where next?