Methylation Support

by Genestra Brands · capsule · 90 vegetarian capsules

  • On the market (NIH)
  • UPC 8 83196 14680 2
  • DSLD label 239080
  • Serving 3 capsules
  • 30 servings

Methylation Support by Genestra Brands lists 6 ingredients, 6 with an amount per serving of 3 capsules, such as 50 mg of vitamin B6, 667 mcg DFE of folate, 800 mcg of vitamin B12 and 75 mg of choline. Its current label entered the NIH Dietary Supplement Label Database on November 21, 2020.

What is in Methylation Support?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Methylation Support: Supplement Facts rows against the market (DSLD label 239080, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B6as Pyridoxal 5-PhosphateVitamin B6 (Form: as Pyridoxal 5-Phosphate)50 mg2,941%Vitamin B6 in Methylation Support against 15,277 products50 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg50 mg

Higher than 87% of 15,277 products listing vitamin B6 (median 6 mg).

Folateas L-5-MTHFFolate (Form: as L-5-MTHF (Alt. Name: Metafolin))667 mcg DFE167%
L-5-Mthf400 mcg
Vitamin B12as MethylcobalaminVitamin B12 (Form: as Methylcobalamin)800 mcg33,333%Vitamin B12 in Methylation Support against 14,425 products800 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg800 mcg

Higher than 88% of 14,425 products listing vitamin B12 (median 36 mcg).

Cholineas Choline BitartrateCholine (Form: as Choline Bitartrate)75 mg14%Choline in Methylation Support against 4,738 products75 mg per serving; the middle half of products list 18 mg to 100 mg, the median 40 mg.DV 550 mgUL 3,500 mg75 mg

Higher than 69% of 4,738 products listing choline (median 40 mg).

Betaine1,500 mgBetaine in Methylation Support against 731 products1,500 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.1,500 mg

Higher than 76% of 731 products listing betaine (median 250 mg).

Source: NIH ODS Dietary Supplement Label Database, label 239080 (entered November 21, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Methylation Support's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Dose: Take 3 capsules daily or as recommended by your health professional.
Warnings
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your healthcare professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 239080.

What else is on the label?

Other ingredients: Hypromellose, Hyprolose, Sunflower Lecithin, Silica.

How many labels does Methylation Support have?

3 labels are on file under this name since January 25, 2016: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 239080 (current) Entered November 21, 2020 · on the market · 90 vegetarian capsules · UPC 8 83196 14680 2
  2. Label 228751 Entered June 24, 2020 · off the market August 21, 2020 · 90 vegetable capsules · UPC 8 83196 14680 2
  3. Label 55592 Entered January 25, 2016 · off the market June 3, 2019 · 90 vegetable capsules · UPC 883196 14680

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Seroyal USA (distributor), Pittsburgh, PA. All Genestra Brands products.

Where next?