PlainVitamins

Cogni Defend

by Clean Nutraceuticals · capsule · 60 capsules

  • On the market (NIH)
  • DSLD label 335580
  • Serving 2 capsules
  • 30 servings

Cogni Defend by Clean Nutraceuticals lists 20 ingredients, 20 with an amount per serving of 2 capsules, such as 90 mg of vitamin C, 500 mcg (20,000 IU) of vitamin D3, 15 mg of vitamin E and 2 mg of vitamin B6. Its current label entered the NIH Dietary Supplement Label Database on September 25, 2025.

What is in Cogni Defend?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Cogni Defend: Supplement Facts rows against the market (DSLD label 335580, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas Ascorbic Acid90 mg100%Vitamin C in Cogni Defend against 18,583 products90 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg90 mg

57% of 18,583 products listing vitamin C give more (median 100 mg).

Vitamin D3as Cholecalciferol500 mcg (20,000 IU)2,500%Vitamin D in Cogni Defend against 14,175 products500 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg500 mcg

Higher than over 99% of 14,175 products listing vitamin D (median 15 mcg). 5 times the adult UL a day.

Vitamin Eas D-Alpha-Tocopherol Succinate15 mg100%
Vitamin B6as Pyridoxine Hydrochloride2 mg118%Vitamin B6 in Cogni Defend against 15,277 products2 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg2 mg

69% of 15,277 products listing vitamin B6 give more (median 6 mg).

Folate340 mcg DFE85%
Folic Acid200 mcg
Vitamin B12as Methylcobalamin100 mcg4,167%Vitamin B12 in Cogni Defend against 14,425 products100 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg100 mcg

Higher than 61% of 14,425 products listing vitamin B12 (median 36 mcg).

Bacopa Whole Plant Extract20:1300 mgBacopa in Cogni Defend against 481 products300 mg per serving; the middle half of products list 100 mg to 300 mg, the median 200 mg.300 mg

Higher than 62% of 481 products listing bacopa (median 200 mg).

Phosphatidylserineas Sunflower Seed Extract10:1300 mgPhosphatidylserine in Cogni Defend against 641 products300 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.300 mg

Higher than 84% of 641 products listing phosphatidylserine (median 100 mg).

Alpha-Glycerylphosphorylcholineas L-Alpha-Glycerylphosphorylcholine50%300 mgAlpha-GPC in Cogni Defend against 656 products300 mg per serving; the middle half of products list 150 mg to 300 mg, the median 200 mg.300 mg

Higher than 53% of 656 products listing alpha-GPC (median 200 mg).

Flaxseed Extractas Linum usitatissimum Seed Extract20:1100 mgFlax in Cogni Defend against 359 products100 mg per serving; the middle half of products list 50 mg to 1,000 mg, the median 200 mg.100 mg

58% of 359 products listing flax give more (median 200 mg).

L-Theanine100 mgTheanine in Cogni Defend against 1,602 products100 mg per serving; the middle half of products list 90 mg to 200 mg, the median 100 mg.100 mg

47% of 1,602 products listing theanine give more (median 100 mg).

Ginkgo biloba Leaf Extract20:1100 mgGinkgo in Cogni Defend against 1,339 products100 mg per serving; the middle half of products list 30 mg to 120 mg, the median 60 mg.100 mg

Higher than 59% of 1,339 products listing ginkgo (median 60 mg).

Cat's Claw Root Extract20:150 mgCat's Claw in Cogni Defend against 300 products50 mg per serving; the middle half of products list 45 mg to 500 mg, the median 200 mg.50 mg

68% of 300 products listing Cat's claw give more (median 200 mg).

Lion's Mane Mushroom Fruiting Body Extract20:150 mgHericium mushroom in Cogni Defend against 373 products50 mg per serving; the middle half of products list 200 mg to 1,000 mg, the median 500 mg.50 mg

91% of 373 products listing hericium mushroom give more (median 500 mg).

Knotweed Root Extractas Polygonum cuspidatum Root Extract20:150 mg
N-Acetyl Cysteine25 mgN-Acetyl Cysteine in Cogni Defend against 1,259 products25 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.25 mg

89% of 1,259 products listing N-acetyl cysteine give more (median 150 mg).

Uridine 5'-Monophosphate Disodium Salt10 mgUridine monophosphate in Cogni Defend against 32 products10 mg per serving; the middle half of products list 68.75 mg to 250 mg, the median 200 mg.10 mg

94% of 32 products listing uridine monophosphate give more (median 200 mg).

Black Pepper fruit extract4:15 mgBlack Pepper in Cogni Defend against 2,363 products5 mg per serving; the middle half of products list 5 mg to 10 mg, the median 5 mg.5 mg

33% of 2,363 products listing black pepper give more (median 5 mg).

Huperzineas Huperzia serrata Whole Plant Extract30:1400 mcgHuperzine in Cogni Defend against 589 products400 mcg per serving; the middle half of products list 50 mcg to 200 mcg, the median 100 mcg.400 mcg

Higher than 86% of 589 products listing huperzine (median 100 mcg).

Source: NIH ODS Dietary Supplement Label Database, label 335580 (entered September 25, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 500 mcg (20,000 IU) of vitamin D, 5 times the adult Tolerable Upper Intake Level.
  • 91% of the 373 products that print an amount of hericium mushroom list more than its 50 mg of Lion's mane mushroom fruiting body extract (filed by NIH under hericium mushroom) (median 500 mg).
  • 89% of the 1,259 products that print an amount of N-acetyl cysteine list more than its 25 mg of N-acetyl cysteine (median 150 mg).
  • 94% of the 32 products that print an amount of uridine monophosphate list more than its 10 mg of uridine 5'-monophosphate disodium salt (filed by NIH under uridine monophosphate) (median 200 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Cogni Defend's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: As a dietary supplement take two (2) capsules once a day. For best results take with a meal and an 8 oz glass of water or as directed by your healthcare professional.
Warnings
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 335580.

What else is on the label?

Other ingredients: Bovine Gelatin, Maltodextrin, Silicon Dioxide, Rice Flour.

How many labels does Cogni Defend have?

One label is on file, entered on September 25, 2025.

  1. Label 335580 (current) Entered September 25, 2025 · on the market · 60 capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Allseason Enterprises, LLC (distributor), Las Vegas, NV. All Clean Nutraceuticals products.

Where next?